U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SNCA synuclein alpha [ Canis lupus familiaris (dog) ]

Gene ID: 478478, updated on 5-Mar-2024

Summary

Official Symbol
SNCAprovided by VGNC
Official Full Name
synuclein alphaprovided by VGNC
Primary source
VGNC:VGNC:46596
See related
Ensembl:ENSCAFG00845019506
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
chromosome: 32
Exon count:
22
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 32 NC_051836.1 (12968680..13133813, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 32 NC_006614.4 (28876711..29040565)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 32 NC_049253.1 (26872693..27039258)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 32 NC_049292.1 (13053952..13218226, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 32 NC_049773.1 (12876233..13041037, complement)

Chromosome 32 - NC_051836.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119867152 Neighboring gene eukaryotic translation initiation factor 3, subunit L pseudogene Neighboring gene multimerin 1 Neighboring gene 60S ribosomal protein L7a-like Neighboring gene small nucleolar RNA SNORD24

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cuprous ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of dopamine secretion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in synapse organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in synaptic vesicle endocytosis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in axon terminus IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051836.1 Reference ROS_Cfam_1.0

    Range
    12968680..13133813 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038444135.1XP_038300063.1  alpha-synuclein isoform X4

    UniProtKB/TrEMBL
    A0A8C0JSY7, A0A8C0PHH6, A0A8I3PAH3, A0A8P0NVF7
    Conserved Domains (1) summary
    pfam01387
    Location:1131
    Synuclein
  2. XM_038444134.1XP_038300062.1  alpha-synuclein isoform X4

    UniProtKB/TrEMBL
    A0A8C0JSY7, A0A8C0PHH6, A0A8I3PAH3, A0A8P0NVF7
    Related
    ENSCAFP00845026956.1, ENSCAFT00845034413.1
    Conserved Domains (1) summary
    pfam01387
    Location:1131
    Synuclein
  3. XM_038444132.1XP_038300060.1  alpha-synuclein isoform X2

    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein
  4. XM_038444131.1XP_038300059.1  alpha-synuclein isoform X1

    UniProtKB/TrEMBL
    A0A8C0PHC9
    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein
  5. XM_038444133.1XP_038300061.1  alpha-synuclein isoform X3

    UniProtKB/TrEMBL
    A0A8I3P4W4, A0A8P0PCH3
    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein
  6. XM_038444136.1XP_038300064.1  alpha-synuclein isoform X5

    UniProtKB/TrEMBL
    A0A8I3NZ19, A0A8P0THC1
    Related
    ENSCAFP00845027123.1, ENSCAFT00845034627.1
    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein

RNA

  1. XR_005305728.1 RNA Sequence

  2. XR_005305732.1 RNA Sequence

  3. XR_005305727.1 RNA Sequence

  4. XR_005305730.1 RNA Sequence

  5. XR_005305731.1 RNA Sequence

  6. XR_005305729.1 RNA Sequence

  7. XR_005305725.1 RNA Sequence

  8. XR_005305726.1 RNA Sequence

  9. XR_005305733.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049292.1 Alternate UMICH_Zoey_3.1

    Range
    13053952..13218226 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038518523.1XP_038374451.1  alpha-synuclein isoform X4

    Conserved Domains (1) summary
    pfam01387
    Location:1131
    Synuclein
  2. XM_038518522.1XP_038374450.1  alpha-synuclein isoform X4

    Conserved Domains (1) summary
    pfam01387
    Location:1131
    Synuclein
  3. XM_038518520.1XP_038374448.1  alpha-synuclein isoform X2

    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein
  4. XM_038518519.1XP_038374447.1  alpha-synuclein isoform X1

    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein
  5. XM_038518521.1XP_038374449.1  alpha-synuclein isoform X3

    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein
  6. XM_038518524.1XP_038374452.1  alpha-synuclein isoform X5

    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein

RNA

  1. XR_005348829.1 RNA Sequence

  2. XR_005348833.1 RNA Sequence

  3. XR_005348828.1 RNA Sequence

  4. XR_005348831.1 RNA Sequence

  5. XR_005348832.1 RNA Sequence

  6. XR_005348830.1 RNA Sequence

  7. XR_005348826.1 RNA Sequence

  8. XR_005348827.1 RNA Sequence

  9. XR_005348834.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049773.1 Alternate UNSW_CanFamBas_1.0

    Range
    12876233..13041037 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038646469.1XP_038502397.1  alpha-synuclein isoform X4

    Conserved Domains (1) summary
    pfam01387
    Location:1131
    Synuclein
  2. XM_038646468.1XP_038502396.1  alpha-synuclein isoform X4

    Conserved Domains (1) summary
    pfam01387
    Location:1131
    Synuclein
  3. XM_038646466.1XP_038502394.1  alpha-synuclein isoform X2

    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein
  4. XM_038646465.1XP_038502393.1  alpha-synuclein isoform X1

    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein
  5. XM_038646467.1XP_038502395.1  alpha-synuclein isoform X3

    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein
  6. XM_038646470.1XP_038502398.1  alpha-synuclein isoform X5

    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein

RNA

  1. XR_005416362.1 RNA Sequence

  2. XR_005416366.1 RNA Sequence

  3. XR_005416361.1 RNA Sequence

  4. XR_005416364.1 RNA Sequence

  5. XR_005416365.1 RNA Sequence

  6. XR_005416363.1 RNA Sequence

  7. XR_005416359.1 RNA Sequence

  8. XR_005416360.1 RNA Sequence

  9. XR_005416367.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049253.1 Alternate UU_Cfam_GSD_1.0

    Range
    26872693..27039258
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038582140.1XP_038438068.1  alpha-synuclein isoform X1

    UniProtKB/TrEMBL
    A0A8C0PHC9
    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein
  2. XM_038582144.1XP_038438072.1  alpha-synuclein isoform X4

    UniProtKB/TrEMBL
    A0A8C0JSY7, A0A8C0PHH6, A0A8I3PAH3, A0A8P0NVF7
    Conserved Domains (1) summary
    pfam01387
    Location:1131
    Synuclein
  3. XM_038582141.1XP_038438069.1  alpha-synuclein isoform X2

    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein
  4. XM_038582142.1XP_038438070.1  alpha-synuclein isoform X3

    UniProtKB/TrEMBL
    A0A8I3P4W4, A0A8P0PCH3
    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein
  5. XM_038582145.1XP_038438073.1  alpha-synuclein isoform X5

    UniProtKB/TrEMBL
    A0A8I3NZ19, A0A8P0THC1
    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein
  6. XM_038582143.1XP_038438071.1  alpha-synuclein isoform X4

    UniProtKB/TrEMBL
    A0A8C0JSY7, A0A8C0PHH6, A0A8I3PAH3, A0A8P0NVF7
    Conserved Domains (1) summary
    pfam01387
    Location:1131
    Synuclein

RNA

  1. XR_005382856.1 RNA Sequence

  2. XR_005382860.1 RNA Sequence

  3. XR_005382853.1 RNA Sequence

  4. XR_005382854.1 RNA Sequence

  5. XR_005382861.1 RNA Sequence

  6. XR_005382855.1 RNA Sequence

  7. XR_005382858.1 RNA Sequence

  8. XR_005382859.1 RNA Sequence

  9. XR_005382857.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006614.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    28876711..29040565
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038462084.1XP_038318012.1  alpha-synuclein isoform X1

    UniProtKB/TrEMBL
    A0A8C0PHC9
    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein
  2. XM_855821.6XP_860914.1  alpha-synuclein isoform X4

    See identical proteins and their annotated locations for XP_860914.1

    UniProtKB/TrEMBL
    A0A8C0JSY7, A0A8C0PHH6, A0A8I3PAH3, A0A8P0NVF7
    Conserved Domains (1) summary
    pfam01387
    Location:1131
    Synuclein
  3. XM_022413536.2XP_022269244.1  alpha-synuclein isoform X2

    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein
  4. XM_022413537.2XP_022269245.1  alpha-synuclein isoform X3

    UniProtKB/TrEMBL
    A0A8I3P4W4, A0A8P0PCH3
    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein
  5. XM_014110040.3XP_013965515.1  alpha-synuclein isoform X5

    UniProtKB/TrEMBL
    A0A8I3NZ19, A0A8P0THC1
    Conserved Domains (1) summary
    pfam01387
    Location:1104
    Synuclein
  6. XM_535656.7XP_535656.1  alpha-synuclein isoform X4

    See identical proteins and their annotated locations for XP_535656.1

    UniProtKB/TrEMBL
    A0A8C0JSY7, A0A8C0PHH6, A0A8I3PAH3, A0A8P0NVF7
    Conserved Domains (1) summary
    pfam01387
    Location:1131
    Synuclein

RNA

  1. XR_002621988.2 RNA Sequence

  2. XR_002621989.2 RNA Sequence

  3. XR_002621983.2 RNA Sequence

  4. XR_002621984.2 RNA Sequence

  5. XR_005317022.1 RNA Sequence

  6. XR_002621986.1 RNA Sequence

  7. XR_002621985.2 RNA Sequence

  8. XR_005317019.1 RNA Sequence

  9. XR_002621987.2 RNA Sequence