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PIAS1 protein inhibitor of activated STAT 1 [ Canis lupus familiaris (dog) ]

Gene ID: 478350, updated on 5-Mar-2024

Summary

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Official Symbol
PIAS1provided by VGNC
Official Full Name
protein inhibitor of activated STAT 1provided by VGNC
Primary source
VGNC:VGNC:44519
See related
Ensembl:ENSCAFG00845018319
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 30
Exon count:
19
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 30 NC_051834.1 (32312019..32428219)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 30 NC_006612.4 (32050874..32167015)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 30 NC_049251.1 (32548145..32664285)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 30 NC_049290.1 (32240403..32356487)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 30 NC_049771.1 (32302308..32418433)

Chromosome 30 - NC_051834.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119866839 Neighboring gene uncharacterized LOC119866926 Neighboring gene uncharacterized LOC111093358 Neighboring gene calmodulin like 4 Neighboring gene CLN6 transmembrane ER protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SUMO ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coregulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein sumoylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 SUMO-protein ligase PIAS1
XP_005638593.1
XP_022268558.2
XP_022268560.1
XP_022268561.1
XP_038298685.1
XP_038298686.1
XP_038298687.1
XP_038298688.1
XP_038298689.1
XP_038298690.1
XP_038317573.1
XP_038373123.1
XP_038373124.1
XP_038373125.1
XP_038373126.1
XP_038373127.1
XP_038373128.1
XP_038436730.1
XP_038436731.1
XP_038436732.1
XP_038436733.1
XP_038436734.1
XP_038436735.1
XP_038501068.1
XP_038501070.1
XP_038501071.1
XP_038501072.1
XP_038501073.1
XP_038501074.1
XP_535524.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051834.1 Reference ROS_Cfam_1.0

    Range
    32312019..32428219
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038442757.1 → XP_038298685.1  E3 SUMO-protein ligase PIAS1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0N9Y3, A0A8I3P120
    Conserved Domains (3) summary
    smart00513
    Location:22 → 56
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:343 → 390
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:148 → 296
    PINIT; PINIT domain

  2. XM_038442762.1 → XP_038298690.1  E3 SUMO-protein ligase PIAS1 isoform X6

    UniProtKB/TrEMBL
    A0A8C0N9Y3, A0A8I3P120
    Conserved Domains (3) summary
    smart00513
    Location:22 → 56
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:343 → 390
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:148 → 296
    PINIT; PINIT domain

  3. XM_038442760.1 → XP_038298688.1  E3 SUMO-protein ligase PIAS1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0K449, A0A8C0N9Y3, A0A8I3P120
    Related
    ENSCAFP00845025662.1, ENSCAFT00845032791.1
    Conserved Domains (3) summary
    smart00513
    Location:11 → 45
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:332 → 379
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:137 → 285
    PINIT; PINIT domain

  4. XM_038442759.1 → XP_038298687.1  E3 SUMO-protein ligase PIAS1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0N9Y3, A0A8I3P120
    Conserved Domains (3) summary
    smart00513
    Location:15 → 49
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:336 → 383
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:141 → 289
    PINIT; PINIT domain

  5. XM_038442761.1 → XP_038298689.1  E3 SUMO-protein ligase PIAS1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0N9Y3, A0A8I3P120, A0A8I3S3B9, A0A8P0PGR2
    Related
    ENSCAFP00845025573.1, ENSCAFT00845032691.1
    Conserved Domains (3) summary
    smart00513
    Location:2 → 36
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:323 → 370
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:128 → 276
    PINIT; PINIT domain

  6. XM_038442758.1 → XP_038298686.1  E3 SUMO-protein ligase PIAS1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0N9Y3, A0A8C0TUF7, A0A8I3NX02, A0A8I3P120
    Related
    ENSCAFP00845025810.1, ENSCAFT00845032984.1
    Conserved Domains (3) summary
    smart00513
    Location:15 → 49
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:336 → 383
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:141 → 289
    PINIT; PINIT domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049290.1 Alternate UMICH_Zoey_3.1

    Range
    32240403..32356487
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038517195.1 → XP_038373123.1  E3 SUMO-protein ligase PIAS1 isoform X1

    Conserved Domains (3) summary
    smart00513
    Location:22 → 56
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:343 → 390
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:148 → 296
    PINIT; PINIT domain

  2. XM_038517200.1 → XP_038373128.1  E3 SUMO-protein ligase PIAS1 isoform X6

    Conserved Domains (3) summary
    smart00513
    Location:22 → 56
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:343 → 390
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:148 → 296
    PINIT; PINIT domain

  3. XM_038517198.1 → XP_038373126.1  E3 SUMO-protein ligase PIAS1 isoform X4

    Conserved Domains (3) summary
    smart00513
    Location:11 → 45
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:332 → 379
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:137 → 285
    PINIT; PINIT domain

  4. XM_038517197.1 → XP_038373125.1  E3 SUMO-protein ligase PIAS1 isoform X3

    Conserved Domains (3) summary
    smart00513
    Location:15 → 49
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:336 → 383
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:141 → 289
    PINIT; PINIT domain

  5. XM_038517199.1 → XP_038373127.1  E3 SUMO-protein ligase PIAS1 isoform X5

    Conserved Domains (3) summary
    smart00513
    Location:2 → 36
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:323 → 370
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:128 → 276
    PINIT; PINIT domain

  6. XM_038517196.1 → XP_038373124.1  E3 SUMO-protein ligase PIAS1 isoform X2

    Conserved Domains (3) summary
    smart00513
    Location:15 → 49
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:336 → 383
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:141 → 289
    PINIT; PINIT domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049771.1 Alternate UNSW_CanFamBas_1.0

    Range
    32302308..32418433
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038645140.1 → XP_038501068.1  E3 SUMO-protein ligase PIAS1 isoform X1

    Conserved Domains (3) summary
    smart00513
    Location:22 → 56
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:343 → 390
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:148 → 296
    PINIT; PINIT domain

  2. XM_038645146.1 → XP_038501074.1  E3 SUMO-protein ligase PIAS1 isoform X6

    Conserved Domains (3) summary
    smart00513
    Location:22 → 56
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:343 → 390
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:148 → 296
    PINIT; PINIT domain

  3. XM_038645144.1 → XP_038501072.1  E3 SUMO-protein ligase PIAS1 isoform X4

    Conserved Domains (3) summary
    smart00513
    Location:11 → 45
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:332 → 379
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:137 → 285
    PINIT; PINIT domain

  4. XM_038645143.1 → XP_038501071.1  E3 SUMO-protein ligase PIAS1 isoform X3

    Conserved Domains (3) summary
    smart00513
    Location:15 → 49
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:336 → 383
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:141 → 289
    PINIT; PINIT domain

  5. XM_038645145.1 → XP_038501073.1  E3 SUMO-protein ligase PIAS1 isoform X5

    Conserved Domains (3) summary
    smart00513
    Location:2 → 36
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:323 → 370
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:128 → 276
    PINIT; PINIT domain

  6. XM_038645142.1 → XP_038501070.1  E3 SUMO-protein ligase PIAS1 isoform X2

    Conserved Domains (3) summary
    smart00513
    Location:15 → 49
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:336 → 383
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:141 → 289
    PINIT; PINIT domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049251.1 Alternate UU_Cfam_GSD_1.0

    Range
    32548145..32664285
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038580802.1 → XP_038436730.1  E3 SUMO-protein ligase PIAS1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0N9Y3, A0A8I3P120
    Conserved Domains (3) summary
    smart00513
    Location:22 → 56
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:343 → 390
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:148 → 296
    PINIT; PINIT domain

  2. XM_038580807.1 → XP_038436735.1  E3 SUMO-protein ligase PIAS1 isoform X6

    UniProtKB/TrEMBL
    A0A8C0N9Y3, A0A8I3P120
    Conserved Domains (3) summary
    smart00513
    Location:22 → 56
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:343 → 390
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:148 → 296
    PINIT; PINIT domain

  3. XM_038580805.1 → XP_038436733.1  E3 SUMO-protein ligase PIAS1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0K449, A0A8C0N9Y3, A0A8I3P120
    Conserved Domains (3) summary
    smart00513
    Location:11 → 45
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:332 → 379
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:137 → 285
    PINIT; PINIT domain

  4. XM_038580804.1 → XP_038436732.1  E3 SUMO-protein ligase PIAS1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0N9Y3, A0A8I3P120
    Conserved Domains (3) summary
    smart00513
    Location:15 → 49
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:336 → 383
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:141 → 289
    PINIT; PINIT domain

  5. XM_038580806.1 → XP_038436734.1  E3 SUMO-protein ligase PIAS1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0N9Y3, A0A8I3P120, A0A8I3S3B9, A0A8P0PGR2
    Conserved Domains (3) summary
    smart00513
    Location:2 → 36
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:323 → 370
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:128 → 276
    PINIT; PINIT domain

  6. XM_038580803.1 → XP_038436731.1  E3 SUMO-protein ligase PIAS1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0N9Y3, A0A8C0TUF7, A0A8I3NX02, A0A8I3P120
    Conserved Domains (3) summary
    smart00513
    Location:15 → 49
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:336 → 383
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:141 → 289
    PINIT; PINIT domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006612.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    32050874..32167015
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022412852.2 → XP_022268560.1  E3 SUMO-protein ligase PIAS1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0N9Y3, A0A8I3P120
    Conserved Domains (3) summary
    smart00513
    Location:22 → 56
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:343 → 390
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:148 → 296
    PINIT; PINIT domain

  2. XM_038461645.1 → XP_038317573.1  E3 SUMO-protein ligase PIAS1 isoform X6

    UniProtKB/TrEMBL
    A0A8C0N9Y3, A0A8I3P120
    Conserved Domains (3) summary
    smart00513
    Location:22 → 56
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:343 → 390
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:148 → 296
    PINIT; PINIT domain

  3. XM_535524.7 → XP_535524.2  E3 SUMO-protein ligase PIAS1 isoform X4

    See identical proteins and their annotated locations for XP_535524.2

    UniProtKB/TrEMBL
    A0A8C0K449, A0A8C0N9Y3, A0A8I3P120
    Conserved Domains (3) summary
    smart00513
    Location:11 → 45
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:332 → 379
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:137 → 285
    PINIT; PINIT domain

  4. XM_022412850.2 → XP_022268558.2  E3 SUMO-protein ligase PIAS1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0N9Y3, A0A8I3P120
    Conserved Domains (3) summary
    smart00513
    Location:15 → 49
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:336 → 383
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:141 → 289
    PINIT; PINIT domain

  5. XM_022412853.2 → XP_022268561.1  E3 SUMO-protein ligase PIAS1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0N9Y3, A0A8I3P120, A0A8I3S3B9, A0A8P0PGR2
    Conserved Domains (3) summary
    smart00513
    Location:2 → 36
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:323 → 370
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:128 → 276
    PINIT; PINIT domain

  6. XM_005638536.4 → XP_005638593.1  E3 SUMO-protein ligase PIAS1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0N9Y3, A0A8C0TUF7, A0A8I3NX02, A0A8I3P120
    Conserved Domains (3) summary
    smart00513
    Location:15 → 49
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:336 → 383
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:141 → 289
    PINIT; PINIT domain
Nucleotide Protein
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