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MAP2K1 mitogen-activated protein kinase kinase 1 [ Canis lupus familiaris (dog) ]

Gene ID: 478347, updated on 5-Mar-2024

Summary

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Official Symbol
MAP2K1provided by VGNC
Official Full Name
mitogen-activated protein kinase kinase 1provided by VGNC
Primary source
VGNC:VGNC:42960
See related
Ensembl:ENSCAFG00845015371
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 30
Exon count:
11
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 30 NC_051834.1 (30879701..30957083)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 30 NC_006612.4 (30613296..30690593)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 30 NC_049251.1 (31110222..31187514)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 30 NC_049290.1 (30809219..30886485)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 30 NC_049771.1 (30868842..30945867)

Chromosome 30 - NC_051834.1Genomic Context describing neighboring genes Neighboring gene small Cajal body-specific RNA 14 Neighboring gene TIMELESS interacting protein Neighboring gene uncharacterized LOC119866838 Neighboring gene uncharacterized LOC119866837 Neighboring gene transfer RNA arginine (anticodon CCU) Neighboring gene small nucleolar RNA SNORD18 Neighboring gene small nucleolar RNA SNORD18 Neighboring gene small nuclear RNA activating complex polypeptide 5 Neighboring gene ribosomal protein L4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dual specificity mitogen-activated protein kinase kinase 1
Names
dual specificity mitogen activated protein kinase kinase 1
NP_001041559.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001048094.2 → NP_001041559.2  dual specificity mitogen-activated protein kinase kinase 1

    Status: VALIDATED

    Source sequence(s)
    JAAUVH010000365
    UniProtKB/TrEMBL
    A0A8C0QXB7, A0A8I3NMM5, A0A8P0NS89
    Related
    ENSCAFP00845021698.1, ENSCAFT00845027576.1
    Conserved Domains (1) summary
    cd06650
    Location:62 → 380
    PKc_MEK1; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase 1

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051834.1 Reference ROS_Cfam_1.0

    Range
    30879701..30957083
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049290.1 Alternate UMICH_Zoey_3.1

    Range
    30809219..30886485
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049771.1 Alternate UNSW_CanFamBas_1.0

    Range
    30868842..30945867
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049251.1 Alternate UU_Cfam_GSD_1.0

    Range
    31110222..31187514
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006612.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    30613296..30690593
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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