LIPC lipase C, hepatic type [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: LIPCprovided by VGNC
Official Full Name: lipase C, hepatic typeprovided by VGNC
Primary source: VGNC:VGNC:42694
See related: Ensembl:ENSCAFG00845015307
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as: HTGL
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 30

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	30	NC_051834.1 (23597357..23749167)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	30	NC_006612.4 (23404560..23555900)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	30	NC_049251.1 (23750266..23901905)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	30	NC_049290.1 (23523240..23674537)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	30	NC_049771.1 (23608314..23759924)

Chromosome 30 - NC_051834.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

REN105I08 (e-PCR)
- UniSTS:264209

UNH115 (e-PCR)
- UniSTS:9538

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables apolipoprotein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables triglyceride lipase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in lipid metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: hepatic triacylglycerol lipase

Names: hepatic triglyceride lipase

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001287090.2 → NP_001274019.2 hepatic triacylglycerol lipase precursor

Status: VALIDATED

Source sequence(s)

JAAUVH010000365

UniProtKB/TrEMBL

A0A8C0KFR8, A0A8C0TWC6, A0A8I3P549, A0A8P0SPQ0

Related

ENSCAFP00845021575.1, ENSCAFT00845027412.1

Conserved Domains (2) summary

cd01758
Location:354 → 489

PLAT_LPL; PLAT/ LH2 domain present in lipoprotein lipase (LPL). LPL is a key enzyme in catabolism of plasma lipoprotein triglycerides (TGs) and has therefeore has a profound influence on triglyceride and high-density lipoprotein (HDL) cholesterol levels in the ...

pfam00151
Location:18 → 351

Lipase