MAPK6 mitogen-activated protein kinase 6 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: MAPK6provided by VGNC
Official Full Name: mitogen-activated protein kinase 6provided by VGNC
Primary source: VGNC:VGNC:42999
See related: Ensembl:ENSCAFG00845026900
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 30

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	30	NC_051834.1 (17849086..17885310)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	30	NC_006612.4 (17629919..17666142)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	30	NC_049251.1 (17992501..18028970)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	30	NC_049290.1 (17768544..17804773)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	30	NC_049771.1 (17886556..17922799)

Chromosome 30 - NC_051834.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

G19713 (e-PCR)
- UniSTS:45867

MAPK6 (e-PCR)
- UniSTS:503158

RH66852 (e-PCR)
- UniSTS:88695

G43355 (e-PCR)
- UniSTS:94948

MAPK6_180.2 (e-PCR)
- UniSTS:462333

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables MAP kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell surface receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: LOW QUALITY PROTEIN: mitogen-activated protein kinase 6; mitogen-activated protein kinase 6

XP_005638475.1

EC 2.7.1.-

EC 2.7.11.24

XP_005638476.1

EC 2.7.1.-

EC 2.7.11.24

XP_038298278.1

EC 2.7.1.-

EC 2.7.11.24

XP_038317344.1

EC 2.7.1.-

EC 2.7.11.24

XP_038372724.1

EC 2.7.1.-

EC 2.7.11.24

XP_038372725.1

EC 2.7.1.-

EC 2.7.11.24

XP_038372726.1

EC 2.7.1.-

EC 2.7.11.24

XP_038372727.1

EC 2.7.1.-

EC 2.7.11.24

XP_038436362.1

EC 2.7.1.-

EC 2.7.11.24

XP_038436363.1

EC 2.7.1.-

EC 2.7.11.24

XP_038436364.1

EC 2.7.1.-

EC 2.7.11.24

XP_038436365.1

EC 2.7.1.-

EC 2.7.11.24

XP_038500663.1

EC 2.7.1.-

EC 2.7.11.24

XP_038500664.1

EC 2.7.1.-

EC 2.7.11.24

XP_038500666.1

EC 2.7.1.-

EC 2.7.11.24

XP_038500667.1

EC 2.7.1.-

EC 2.7.11.24

XP_863166.2

EC 2.7.1.-

EC 2.7.11.24

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051834.1 Reference ROS_Cfam_1.0

Range

17849086..17885310

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038442350.1 → XP_038298278.1 LOW QUALITY PROTEIN: mitogen-activated protein kinase 6

UniProtKB/TrEMBL

A0A8I3PQY7

Related

ENSCAFP00845037201.1, ENSCAFT00845047414.1

Conserved Domains (1) summary

cd07854
Location:14 → 355

STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

Alternate UMICH_Zoey_3.1

Genomic

NC_049290.1 Alternate UMICH_Zoey_3.1

Range

17768544..17804773

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038516796.1 → XP_038372724.1 mitogen-activated protein kinase 6

Conserved Domains (1) summary

cd07854
Location:14 → 355

STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)
XM_038516799.1 → XP_038372727.1 mitogen-activated protein kinase 6

Conserved Domains (1) summary

cd07854
Location:14 → 355

STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)
XM_038516798.1 → XP_038372726.1 mitogen-activated protein kinase 6

Conserved Domains (1) summary

cd07854
Location:14 → 355

STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)
XM_038516797.1 → XP_038372725.1 mitogen-activated protein kinase 6

Conserved Domains (1) summary

cd07854
Location:14 → 355

STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049771.1 Alternate UNSW_CanFamBas_1.0

Range

17886556..17922799

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038644735.1 → XP_038500663.1 mitogen-activated protein kinase 6

Conserved Domains (1) summary

cd07854
Location:14 → 355

STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)
XM_038644739.1 → XP_038500667.1 mitogen-activated protein kinase 6

Conserved Domains (1) summary

cd07854
Location:14 → 355

STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)
XM_038644738.1 → XP_038500666.1 mitogen-activated protein kinase 6

Conserved Domains (1) summary

cd07854
Location:14 → 355

STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)
XM_038644736.1 → XP_038500664.1 mitogen-activated protein kinase 6

Conserved Domains (1) summary

cd07854
Location:14 → 355

STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049251.1 Alternate UU_Cfam_GSD_1.0

Range

17992501..18028970

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038580434.1 → XP_038436362.1 mitogen-activated protein kinase 6

UniProtKB/TrEMBL

A0A8C0L5U2, A0A8C0TRN7, A0A8I3PQY7, A0A8P0SQ67

Conserved Domains (1) summary

cd07854
Location:14 → 355

STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)
XM_038580437.1 → XP_038436365.1 mitogen-activated protein kinase 6

UniProtKB/TrEMBL

A0A8C0L5U2, A0A8C0TRN7, A0A8I3PQY7, A0A8P0SQ67

Conserved Domains (1) summary

cd07854
Location:14 → 355

STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)
XM_038580436.1 → XP_038436364.1 mitogen-activated protein kinase 6

UniProtKB/TrEMBL

A0A8C0L5U2, A0A8C0TRN7, A0A8I3PQY7, A0A8P0SQ67

Conserved Domains (1) summary

cd07854
Location:14 → 355

STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)
XM_038580435.1 → XP_038436363.1 mitogen-activated protein kinase 6

UniProtKB/TrEMBL

A0A8C0L5U2, A0A8C0TRN7, A0A8I3PQY7, A0A8P0SQ67

Conserved Domains (1) summary

cd07854
Location:14 → 355

STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006612.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

17629919..17666142

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_858073.6 → XP_863166.2 mitogen-activated protein kinase 6

See identical proteins and their annotated locations for XP_863166.2

UniProtKB/TrEMBL

A0A8C0L5U2, A0A8C0TRN7, A0A8I3PQY7, A0A8P0SQ67

Conserved Domains (1) summary

cd07854
Location:14 → 355

STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)
XM_038461416.1 → XP_038317344.1 mitogen-activated protein kinase 6

UniProtKB/TrEMBL

A0A8C0L5U2, A0A8C0TRN7, A0A8I3PQY7, A0A8P0SQ67

Conserved Domains (1) summary

cd07854
Location:14 → 355

STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)
XM_005638419.4 → XP_005638476.1 mitogen-activated protein kinase 6

See identical proteins and their annotated locations for XP_005638476.1

UniProtKB/TrEMBL

A0A8C0L5U2, A0A8C0TRN7, A0A8I3PQY7, A0A8P0SQ67

Conserved Domains (1) summary

cd07854
Location:14 → 355

STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)
XM_005638418.4 → XP_005638475.1 mitogen-activated protein kinase 6

See identical proteins and their annotated locations for XP_005638475.1

UniProtKB/TrEMBL

A0A8C0L5U2, A0A8C0TRN7, A0A8I3PQY7, A0A8P0SQ67

Conserved Domains (1) summary

cd07854
Location:14 → 355

STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)