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KDM1A lysine demethylase 1A [ Canis lupus familiaris (dog) ]

Gene ID: 478193, updated on 5-Mar-2024

Summary

Official Symbol
KDM1Aprovided by VGNC
Official Full Name
lysine demethylase 1Aprovided by VGNC
Primary source
VGNC:VGNC:42318
See related
Ensembl:ENSCAFG00845000177
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
AOF2; KDM1
Orthologs
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Genomic context

Location:
chromosome: 2
Exon count:
21
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 2 NC_051806.1 (76872072..76934039, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 2 NC_006584.4 (72818576..72880479, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 2 NC_049223.1 (75705895..75767600, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 2 NC_049262.1 (73694139..73755941, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 2 NC_049743.1 (74702184..74764063, complement)

Chromosome 2 - NC_051806.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111093602 Neighboring gene 5-hydroxytryptamine receptor 1D Neighboring gene proline-rich protein 2-like Neighboring gene leucine zipper protein 1 Neighboring gene testis expressed 46 Neighboring gene lactamase beta like 1

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
lysine-specific histone demethylase 1A
Names
amine oxidase (flavin containing) domain 2
lysine (K)-specific demethylase 1
XP_005617878.1
XP_038326718.1
XP_038326719.1
XP_038326720.1
XP_038387581.1
XP_038387582.1
XP_038387583.1
XP_038451811.1
XP_038451812.1
XP_038451813.1
XP_038515890.1
XP_038515891.1
XP_038515892.1
XP_535366.2
XP_866610.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051806.1 Reference ROS_Cfam_1.0

    Range
    76872072..76934039 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038659964.1XP_038515892.1  lysine-specific histone demethylase 1A isoform X3

    UniProtKB/TrEMBL
    A0A8C0L0B5
    Conserved Domains (2) summary
    PLN02328
    Location:184826
    PLN02328; lysine-specific histone demethylase 1 homolog
    PHA03378
    Location:3999
    PHA03378; EBNA-3B; Provisional
  2. XM_038659963.1XP_038515891.1  lysine-specific histone demethylase 1A isoform X2

    UniProtKB/TrEMBL
    A0A8C0PWR1, A0A8I3MA21
    Related
    ENSCAFP00845000200.1, ENSCAFT00845000287.1
    Conserved Domains (2) summary
    PLN02328
    Location:204846
    PLN02328; lysine-specific histone demethylase 1 homolog
    PHA03378
    Location:3999
    PHA03378; EBNA-3B; Provisional
  3. XM_038659962.1XP_038515890.1  lysine-specific histone demethylase 1A isoform X1

    UniProtKB/TrEMBL
    A0A8C0M261, A0A8I3RNY9
    Related
    ENSCAFP00845000198.1, ENSCAFT00845000283.1
    Conserved Domains (2) summary
    PLN02328
    Location:204850
    PLN02328; lysine-specific histone demethylase 1 homolog
    PHA03378
    Location:3999
    PHA03378; EBNA-3B; Provisional

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049262.1 Alternate UMICH_Zoey_3.1

    Range
    73694139..73755941 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038470792.1XP_038326720.1  lysine-specific histone demethylase 1A isoform X3

    Conserved Domains (2) summary
    PLN02328
    Location:184826
    PLN02328; lysine-specific histone demethylase 1 homolog
    PHA03378
    Location:3999
    PHA03378; EBNA-3B; Provisional
  2. XM_038470791.1XP_038326719.1  lysine-specific histone demethylase 1A isoform X2

    Conserved Domains (2) summary
    PLN02328
    Location:204846
    PLN02328; lysine-specific histone demethylase 1 homolog
    PHA03378
    Location:3999
    PHA03378; EBNA-3B; Provisional
  3. XM_038470790.1XP_038326718.1  lysine-specific histone demethylase 1A isoform X1

    Conserved Domains (2) summary
    PLN02328
    Location:204850
    PLN02328; lysine-specific histone demethylase 1 homolog
    PHA03378
    Location:3999
    PHA03378; EBNA-3B; Provisional

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049743.1 Alternate UNSW_CanFamBas_1.0

    Range
    74702184..74764063 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038595885.1XP_038451813.1  lysine-specific histone demethylase 1A isoform X3

    Conserved Domains (2) summary
    PLN02328
    Location:184826
    PLN02328; lysine-specific histone demethylase 1 homolog
    PHA03378
    Location:3999
    PHA03378; EBNA-3B; Provisional
  2. XM_038595884.1XP_038451812.1  lysine-specific histone demethylase 1A isoform X2

    Conserved Domains (2) summary
    PLN02328
    Location:204846
    PLN02328; lysine-specific histone demethylase 1 homolog
    PHA03378
    Location:3999
    PHA03378; EBNA-3B; Provisional
  3. XM_038595883.1XP_038451811.1  lysine-specific histone demethylase 1A isoform X1

    Conserved Domains (2) summary
    PLN02328
    Location:204850
    PLN02328; lysine-specific histone demethylase 1 homolog
    PHA03378
    Location:3999
    PHA03378; EBNA-3B; Provisional

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049223.1 Alternate UU_Cfam_GSD_1.0

    Range
    75705895..75767600 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038531655.1XP_038387583.1  lysine-specific histone demethylase 1A isoform X3

    UniProtKB/TrEMBL
    A0A8C0L0B5
    Conserved Domains (2) summary
    PLN02328
    Location:184826
    PLN02328; lysine-specific histone demethylase 1 homolog
    PHA03378
    Location:3999
    PHA03378; EBNA-3B; Provisional
  2. XM_038531654.1XP_038387582.1  lysine-specific histone demethylase 1A isoform X2

    UniProtKB/TrEMBL
    A0A8C0PWR1, A0A8I3MA21
    Conserved Domains (2) summary
    PLN02328
    Location:204846
    PLN02328; lysine-specific histone demethylase 1 homolog
    PHA03378
    Location:3999
    PHA03378; EBNA-3B; Provisional
  3. XM_038531653.1XP_038387581.1  lysine-specific histone demethylase 1A isoform X1

    UniProtKB/TrEMBL
    A0A8C0M261, A0A8I3RNY9
    Conserved Domains (2) summary
    PLN02328
    Location:204850
    PLN02328; lysine-specific histone demethylase 1 homolog
    PHA03378
    Location:3999
    PHA03378; EBNA-3B; Provisional

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    72818576..72880479 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_861517.5XP_866610.1  lysine-specific histone demethylase 1A isoform X3

    UniProtKB/TrEMBL
    A0A8C0L0B5
    Conserved Domains (2) summary
    PLN02328
    Location:184826
    PLN02328; lysine-specific histone demethylase 1 homolog
    PHA03378
    Location:3999
    PHA03378; EBNA-3B; Provisional
  2. XM_005617821.3XP_005617878.1  lysine-specific histone demethylase 1A isoform X2

    UniProtKB/TrEMBL
    A0A8C0PWR1, A0A8I3MA21
    Conserved Domains (2) summary
    PLN02328
    Location:204846
    PLN02328; lysine-specific histone demethylase 1 homolog
    PHA03378
    Location:3999
    PHA03378; EBNA-3B; Provisional
  3. XM_535366.7XP_535366.2  lysine-specific histone demethylase 1A isoform X1

    UniProtKB/TrEMBL
    A0A8C0M261, A0A8I3RNY9
    Conserved Domains (2) summary
    PLN02328
    Location:204850
    PLN02328; lysine-specific histone demethylase 1 homolog
    PHA03378
    Location:3999
    PHA03378; EBNA-3B; Provisional