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MCM4 minichromosome maintenance complex component 4 [ Canis lupus familiaris (dog) ]

Gene ID: 477871, updated on 5-Mar-2024

Summary

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Official Symbol
MCM4provided by VGNC
Official Full Name
minichromosome maintenance complex component 4provided by VGNC
Primary source
VGNC:VGNC:43084
See related
Ensembl:ENSCAFG00845028253
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 29
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 29 NC_051833.1 (242674..259603)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 29 NC_006611.4 (670093..687010)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 29 NC_049250.1 (504123..521263)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 29 NC_049289.1 (241027..256505)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 29 NC_049770.1 (435880..453002)

Chromosome 29 - NC_051833.1Genomic Context describing neighboring genes Neighboring gene protein kinase, DNA-activated, catalytic subunit Neighboring gene cytochrome c oxidase subunit 7B, mitochondrial-like Neighboring gene ubiquitin conjugating enzyme E2 V2 Neighboring gene bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA strand elongation involved in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA unwinding involved in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in double-strand break repair via break-induced replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic DNA replication initiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of MCM complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA replication licensing factor MCM4
XP_038297058.1
XP_038371625.1
XP_038371626.1
XP_038435191.1
XP_038499431.1
XP_535063.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051833.1 Reference ROS_Cfam_1.0

    Range
    242674..259603
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038441130.1 → XP_038297058.1  DNA replication licensing factor MCM4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KRU4, A0A8C0P8X4, A0A8C0P9M1, A0A8I3PWX9
    Related
    ENSCAFP00845039109.1, ENSCAFT00845049869.1
    Conserved Domains (2) summary
    smart00350
    Location:267 → 770
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:163 → 263
    MCM_N; MCM N-terminal domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049289.1 Alternate UMICH_Zoey_3.1

    Range
    241027..256505
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038515697.1 → XP_038371625.1  DNA replication licensing factor MCM4 isoform X2

  2. XM_038515698.1 → XP_038371626.1  DNA replication licensing factor MCM4 isoform X3

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049770.1 Alternate UNSW_CanFamBas_1.0

    Range
    435880..453002
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038643503.1 → XP_038499431.1  DNA replication licensing factor MCM4 isoform X1

    Conserved Domains (2) summary
    smart00350
    Location:267 → 770
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:163 → 263
    MCM_N; MCM N-terminal domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049250.1 Alternate UU_Cfam_GSD_1.0

    Range
    504123..521263
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038579263.1 → XP_038435191.1  DNA replication licensing factor MCM4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0P9M1

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006611.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    670093..687010
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_535063.7 → XP_535063.3  DNA replication licensing factor MCM4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KRU4, A0A8C0P8X4, A0A8C0P9M1, A0A8I3PWX9
    Conserved Domains (2) summary
    smart00350
    Location:267 → 770
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:163 → 263
    MCM_N; MCM N-terminal domain
Nucleotide Protein
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