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ADCY6 adenylate cyclase 6 [ Canis lupus familiaris (dog) ]

Gene ID: 477625, updated on 5-Mar-2024

Summary

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Official Symbol
ADCY6provided by VGNC
Official Full Name
adenylate cyclase 6provided by VGNC
Primary source
VGNC:VGNC:37623
See related
Ensembl:ENSCAFG00845024352
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 27
Exon count:
26
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 27 NC_051831.1 (5784673..5805753)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 27 NC_006609.4 (40504946..40518306, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 27 NC_049248.1 (40897201..40910552, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 27 NC_049287.1 (5754314..5767654)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 27 NC_049768.1 (5744379..5757707)

Chromosome 27 - NC_051831.1Genomic Context describing neighboring genes Neighboring gene DEAD-box helicase 23 Neighboring gene calcium voltage-gated channel auxiliary subunit beta 3 Neighboring gene sperm microtubule inner protein 11 Neighboring gene cyclin T1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning and characterization of a sixth adenylyl cyclase isoform: types V and VI constitute a subgroup within the mammalian adenylyl cyclase family. Katsushika S, et al. Proc Natl Acad Sci U S A, 1992 Sep 15. PMID 1528892, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables adenylate cyclase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cAMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
adenylate cyclase type 6
Names
ATP pyrophosphate-lyase 6
Adenylate cyclase type VI
Adenylyl cyclase 6
Ca(2+)-inhibitable adenylyl cyclase
NP_001182076.1
XP_038293690.1
XP_038293691.1
XP_038293692.1
XP_038293693.1
XP_038293694.1
XP_038293695.1
XP_038293696.1
XP_038293697.1
XP_038293698.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195147.2 → NP_001182076.1  adenylate cyclase type 6

    See identical proteins and their annotated locations for NP_001182076.1

    Status: VALIDATED

    Source sequence(s)
    JAAUVH010000362
    UniProtKB/TrEMBL
    A0A8C0KH29, A0A8C0P6Z2, A0A8C0TWL8
    Related
    ENSCAFP00845034025.1, ENSCAFT00845043430.1
    Conserved Domains (3) summary
    pfam00211
    Location:968 → 1162
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:14 → 366
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:580 → 666
    DUF1053; Domain of Unknown Function (DUF1053)

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051831.1 Reference ROS_Cfam_1.0

    Range
    5784673..5805753
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038437763.1 → XP_038293691.1  adenylate cyclase type 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TWL8
    Conserved Domains (3) summary
    pfam00211
    Location:976 → 1170
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:14 → 366
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:580 → 674
    DUF1053; Domain of Unknown Function (DUF1053)

  2. XM_038437762.1 → XP_038293690.1  adenylate cyclase type 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TWL8
    Conserved Domains (3) summary
    pfam00211
    Location:976 → 1170
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:14 → 366
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:580 → 674
    DUF1053; Domain of Unknown Function (DUF1053)

  3. XM_038437770.1 → XP_038293698.1  adenylate cyclase type 6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KH29, A0A8C0P6Z2, A0A8C0TWL8
    Conserved Domains (3) summary
    pfam00211
    Location:968 → 1162
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:14 → 366
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:580 → 666
    DUF1053; Domain of Unknown Function (DUF1053)

  4. XM_038437764.1 → XP_038293692.1  adenylate cyclase type 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TWL8
    Conserved Domains (3) summary
    pfam00211
    Location:976 → 1170
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:14 → 366
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:580 → 674
    DUF1053; Domain of Unknown Function (DUF1053)

  5. XM_038437768.1 → XP_038293696.1  adenylate cyclase type 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TWL8
    Conserved Domains (3) summary
    pfam00211
    Location:976 → 1170
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:14 → 366
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:580 → 674
    DUF1053; Domain of Unknown Function (DUF1053)

  6. XM_038437769.1 → XP_038293697.1  adenylate cyclase type 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TWL8
    Conserved Domains (3) summary
    pfam00211
    Location:976 → 1170
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:14 → 366
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:580 → 674
    DUF1053; Domain of Unknown Function (DUF1053)

  7. XM_038437767.1 → XP_038293695.1  adenylate cyclase type 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TWL8
    Conserved Domains (3) summary
    pfam00211
    Location:976 → 1170
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:14 → 366
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:580 → 674
    DUF1053; Domain of Unknown Function (DUF1053)

  8. XM_038437765.1 → XP_038293693.1  adenylate cyclase type 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TWL8
    Conserved Domains (3) summary
    pfam00211
    Location:976 → 1170
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:14 → 366
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:580 → 674
    DUF1053; Domain of Unknown Function (DUF1053)

  9. XM_038437766.1 → XP_038293694.1  adenylate cyclase type 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TWL8
    Conserved Domains (3) summary
    pfam00211
    Location:976 → 1170
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:14 → 366
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:580 → 674
    DUF1053; Domain of Unknown Function (DUF1053)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049287.1 Alternate UMICH_Zoey_3.1

    Range
    5754314..5767654
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049768.1 Alternate UNSW_CanFamBas_1.0

    Range
    5744379..5757707
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049248.1 Alternate UU_Cfam_GSD_1.0

    Range
    40897201..40910552 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006609.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    40504946..40518306 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P30804.1 GenPept UniProtKB/Swiss-Prot:P30804

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