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FDFT1 farnesyl-diphosphate farnesyltransferase 1 [ Canis lupus familiaris (dog) ]

Gene ID: 477362, updated on 5-Mar-2024

Summary

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Official Symbol
FDFT1provided by VGNC
Official Full Name
farnesyl-diphosphate farnesyltransferase 1provided by VGNC
Primary source
VGNC:VGNC:40811
See related
Ensembl:ENSCAFG00845018898
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 25
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 25 NC_051829.1 (26215096..26248206, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 25 NC_006607.4 (26717027..26750517, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 25 NC_049246.1 (26216048..26249367, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 25 NC_049285.1 (26160696..26194180, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 25 NC_049766.1 (26064844..26097943, complement)

Chromosome 25 - NC_051829.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119865843 Neighboring gene cathepsin B Neighboring gene nei like DNA glycosylase 2 Neighboring gene GATA binding protein 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables farnesyl-diphosphate farnesyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables squalene synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cholesterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in farnesyl diphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
squalene synthase
XP_013963030.2
XP_038291162.1
XP_038291164.1
XP_038366109.1
XP_038366110.1
XP_038429572.1
XP_038429573.1
XP_038493873.1
XP_038493874.1
XP_534557.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051829.1 Reference ROS_Cfam_1.0

    Range
    26215096..26248206 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038435234.1 → XP_038291162.1  squalene synthase isoform X1

    UniProtKB/TrEMBL
    A0A8C0NTL6, A0A8I3P8C5
    Related
    ENSCAFP00845026304.1, ENSCAFT00845033597.1
    Conserved Domains (1) summary
    cl00210
    Location:94 → 426
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

  2. XM_038435236.1 → XP_038291164.1  squalene synthase isoform X2

    UniProtKB/TrEMBL
    A0A8C0KHY3, A0A8C0NYS2, A0A8C0TGW2, A0A8I3NXT8, A0A8I3P3D2
    Related
    ENSCAFP00845026204.1, ENSCAFT00845033474.1
    Conserved Domains (1) summary
    cl00210
    Location:38 → 370
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049285.1 Alternate UMICH_Zoey_3.1

    Range
    26160696..26194180 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038510181.1 → XP_038366109.1  squalene synthase isoform X1

    Conserved Domains (1) summary
    cl00210
    Location:94 → 426
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

  2. XM_038510182.1 → XP_038366110.1  squalene synthase isoform X2

    Conserved Domains (1) summary
    cl00210
    Location:38 → 370
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049766.1 Alternate UNSW_CanFamBas_1.0

    Range
    26064844..26097943 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038637945.1 → XP_038493873.1  squalene synthase isoform X1

    Conserved Domains (1) summary
    cl00210
    Location:94 → 426
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

  2. XM_038637946.1 → XP_038493874.1  squalene synthase isoform X2

    Conserved Domains (1) summary
    cl00210
    Location:38 → 370
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049246.1 Alternate UU_Cfam_GSD_1.0

    Range
    26216048..26249367 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038573644.1 → XP_038429572.1  squalene synthase isoform X1

    UniProtKB/TrEMBL
    A0A8C0NTL6, A0A8I3P8C5
    Conserved Domains (1) summary
    cl00210
    Location:94 → 426
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

  2. XM_038573645.1 → XP_038429573.1  squalene synthase isoform X2

    UniProtKB/TrEMBL
    A0A8C0KHY3, A0A8C0NYS2, A0A8C0TGW2, A0A8I3NXT8, A0A8I3P3D2
    Conserved Domains (1) summary
    cl00210
    Location:38 → 370
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006607.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    26717027..26750517 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014107555.3 → XP_013963030.2  squalene synthase isoform X1

    UniProtKB/TrEMBL
    A0A8C0NTL6, A0A8I3P8C5
    Conserved Domains (1) summary
    cl00210
    Location:94 → 426
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

  2. XM_534557.7 → XP_534557.2  squalene synthase isoform X2

    UniProtKB/TrEMBL
    A0A8C0KHY3, A0A8C0NYS2, A0A8C0TGW2, A0A8I3NXT8, A0A8I3P3D2
    Conserved Domains (1) summary
    cl00210
    Location:38 → 370
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1
Nucleotide Protein
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