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RBL1 RB transcriptional corepressor like 1 [ Canis lupus familiaris (dog) ]

Gene ID: 477221, updated on 5-Mar-2024

Summary

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Official Symbol
RBL1provided by VGNC
Official Full Name
RB transcriptional corepressor like 1provided by VGNC
Primary source
VGNC:VGNC:45402
See related
Ensembl:ENSCAFG00845027052
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 24
Exon count:
24
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 24 NC_051828.1 (26395755..26454244, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 24 NC_006606.4 (25346666..25405658, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 24 NC_049245.1 (26267110..26325939, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 24 NC_049284.1 (25673462..25732016, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 24 NC_049765.1 (25777693..25836916, complement)

Chromosome 24 - NC_051828.1Genomic Context describing neighboring genes Neighboring gene microtubule crosslinking factor 2 Neighboring gene TBC/LysM-associated domain containing 2 Neighboring gene SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Neighboring gene uncharacterized LOC111092069 Neighboring gene uncharacterized LOC111092070 Neighboring gene maestro heat like repeat family member 8 Neighboring gene ribophorin II

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of G1/S transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of chromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
retinoblastoma-like protein 1
Names
retinoblastoma-like 1 (p107)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051828.1 Reference ROS_Cfam_1.0

    Range
    26395755..26454244 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038433762.1 → XP_038289690.1  retinoblastoma-like protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SKW5
    Conserved Domains (4) summary
    pfam01858
    Location:385 → 578
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:902 → 987
    Rb_C; Rb C-terminal domain
    pfam11934
    Location:77 → 209
    DUF3452; Domain of unknown function (DUF3452)
    cl40454
    Location:781 → 890
    CYCLIN_SF; Cyclin box fold superfamily

  2. XM_038433761.1 → XP_038289689.1  retinoblastoma-like protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QZQ2, A0A8C0SJ08, A0A8C0SKW5, A0A8I3Q0G8
    Related
    ENSCAFP00845037438.1, ENSCAFT00845047710.1
    Conserved Domains (4) summary
    pfam01858
    Location:385 → 578
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:961 → 1046
    Rb_C; Rb C-terminal domain
    pfam11934
    Location:77 → 209
    DUF3452; Domain of unknown function (DUF3452)
    cd20605
    Location:781 → 949
    CYCLIN_RBL1; cyclin box found in retinoblastoma-like protein 1 (RBL1) and similar proteins

  3. XM_038433764.1 → XP_038289692.1  retinoblastoma-like protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0SKW5
    Conserved Domains (4) summary
    pfam01858
    Location:281 → 474
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:857 → 942
    Rb_C; Rb C-terminal domain
    pfam11934
    Location:1 → 105
    DUF3452; Domain of unknown function (DUF3452)
    cd20605
    Location:677 → 845
    CYCLIN_RBL1; cyclin box found in retinoblastoma-like protein 1 (RBL1) and similar proteins

  4. XM_038433763.1 → XP_038289691.1  retinoblastoma-like protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0SKW5
    Conserved Domains (4) summary
    pfam01858
    Location:306 → 499
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:882 → 967
    Rb_C; Rb C-terminal domain
    pfam11934
    Location:1 → 130
    DUF3452; Domain of unknown function (DUF3452)
    cd20605
    Location:702 → 870
    CYCLIN_RBL1; cyclin box found in retinoblastoma-like protein 1 (RBL1) and similar proteins

  5. XM_038433766.1 → XP_038289694.1  retinoblastoma-like protein 1 isoform X6

    Conserved Domains (3) summary
    pfam01858
    Location:1 → 155
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:538 → 623
    Rb_C; Rb C-terminal domain
    cd20605
    Location:358 → 526
    CYCLIN_RBL1; cyclin box found in retinoblastoma-like protein 1 (RBL1) and similar proteins

  6. XM_038433765.1 → XP_038289693.1  retinoblastoma-like protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0KHC1
    Conserved Domains (3) summary
    pfam01858
    Location:385 → 578
    RB_A; Retinoblastoma-associated protein A domain
    pfam11934
    Location:77 → 209
    DUF3452; Domain of unknown function (DUF3452)
    cl40454
    Location:781 → 855
    CYCLIN_SF; Cyclin box fold superfamily

RNA

  1. XR_005300918.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049284.1 Alternate UMICH_Zoey_3.1

    Range
    25673462..25732016 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038508926.1 → XP_038364854.1  retinoblastoma-like protein 1 isoform X2

    Conserved Domains (4) summary
    pfam01858
    Location:385 → 578
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:902 → 987
    Rb_C; Rb C-terminal domain
    pfam11934
    Location:77 → 209
    DUF3452; Domain of unknown function (DUF3452)
    cl40454
    Location:781 → 890
    CYCLIN_SF; Cyclin box fold superfamily

  2. XM_038508925.1 → XP_038364853.1  retinoblastoma-like protein 1 isoform X1

    Conserved Domains (4) summary
    pfam01858
    Location:385 → 578
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:961 → 1046
    Rb_C; Rb C-terminal domain
    pfam11934
    Location:77 → 209
    DUF3452; Domain of unknown function (DUF3452)
    cd20605
    Location:781 → 949
    CYCLIN_RBL1; cyclin box found in retinoblastoma-like protein 1 (RBL1) and similar proteins

  3. XM_038508928.1 → XP_038364856.1  retinoblastoma-like protein 1 isoform X4

    Conserved Domains (4) summary
    pfam01858
    Location:281 → 474
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:857 → 942
    Rb_C; Rb C-terminal domain
    pfam11934
    Location:1 → 105
    DUF3452; Domain of unknown function (DUF3452)
    cd20605
    Location:677 → 845
    CYCLIN_RBL1; cyclin box found in retinoblastoma-like protein 1 (RBL1) and similar proteins

  4. XM_038508927.1 → XP_038364855.1  retinoblastoma-like protein 1 isoform X3

    Conserved Domains (4) summary
    pfam01858
    Location:306 → 499
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:882 → 967
    Rb_C; Rb C-terminal domain
    pfam11934
    Location:1 → 130
    DUF3452; Domain of unknown function (DUF3452)
    cd20605
    Location:702 → 870
    CYCLIN_RBL1; cyclin box found in retinoblastoma-like protein 1 (RBL1) and similar proteins

  5. XM_038508930.1 → XP_038364858.1  retinoblastoma-like protein 1 isoform X6

    Conserved Domains (3) summary
    pfam01858
    Location:1 → 155
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:538 → 623
    Rb_C; Rb C-terminal domain
    cd20605
    Location:358 → 526
    CYCLIN_RBL1; cyclin box found in retinoblastoma-like protein 1 (RBL1) and similar proteins

  6. XM_038508929.1 → XP_038364857.1  retinoblastoma-like protein 1 isoform X5

    Conserved Domains (3) summary
    pfam01858
    Location:385 → 578
    RB_A; Retinoblastoma-associated protein A domain
    pfam11934
    Location:77 → 209
    DUF3452; Domain of unknown function (DUF3452)
    cl40454
    Location:781 → 855
    CYCLIN_SF; Cyclin box fold superfamily

RNA

  1. XR_005344015.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049765.1 Alternate UNSW_CanFamBas_1.0

    Range
    25777693..25836916 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038636500.1 → XP_038492428.1  retinoblastoma-like protein 1 isoform X2

  2. XM_038636499.1 → XP_038492427.1  retinoblastoma-like protein 1 isoform X1

  3. XM_038636502.1 → XP_038492430.1  retinoblastoma-like protein 1 isoform X4

  4. XM_038636501.1 → XP_038492429.1  retinoblastoma-like protein 1 isoform X3

  5. XM_038636504.1 → XP_038492432.1  retinoblastoma-like protein 1 isoform X6

    Conserved Domains (3) summary
    pfam01858
    Location:1 → 155
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:538 → 623
    Rb_C; Rb C-terminal domain
    cd20605
    Location:358 → 526
    CYCLIN_RBL1; cyclin box found in retinoblastoma-like protein 1 (RBL1) and similar proteins

  6. XM_038636503.1 → XP_038492431.1  retinoblastoma-like protein 1 isoform X5

RNA

  1. XR_005411694.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049245.1 Alternate UU_Cfam_GSD_1.0

    Range
    26267110..26325939 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038572243.1 → XP_038428171.1  retinoblastoma-like protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SKW5
    Conserved Domains (4) summary
    pfam01858
    Location:385 → 578
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:902 → 987
    Rb_C; Rb C-terminal domain
    pfam11934
    Location:77 → 209
    DUF3452; Domain of unknown function (DUF3452)
    cl40454
    Location:781 → 890
    CYCLIN_SF; Cyclin box fold superfamily

  2. XM_038572242.1 → XP_038428170.1  retinoblastoma-like protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QZQ2, A0A8C0SJ08, A0A8C0SKW5, A0A8I3Q0G8
    Conserved Domains (4) summary
    pfam01858
    Location:385 → 578
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:961 → 1046
    Rb_C; Rb C-terminal domain
    pfam11934
    Location:77 → 209
    DUF3452; Domain of unknown function (DUF3452)
    cd20605
    Location:781 → 949
    CYCLIN_RBL1; cyclin box found in retinoblastoma-like protein 1 (RBL1) and similar proteins

  3. XM_038572245.1 → XP_038428173.1  retinoblastoma-like protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0SKW5
    Conserved Domains (4) summary
    pfam01858
    Location:281 → 474
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:857 → 942
    Rb_C; Rb C-terminal domain
    pfam11934
    Location:1 → 105
    DUF3452; Domain of unknown function (DUF3452)
    cd20605
    Location:677 → 845
    CYCLIN_RBL1; cyclin box found in retinoblastoma-like protein 1 (RBL1) and similar proteins

  4. XM_038572244.1 → XP_038428172.1  retinoblastoma-like protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0SKW5
    Conserved Domains (4) summary
    pfam01858
    Location:306 → 499
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:882 → 967
    Rb_C; Rb C-terminal domain
    pfam11934
    Location:1 → 130
    DUF3452; Domain of unknown function (DUF3452)
    cd20605
    Location:702 → 870
    CYCLIN_RBL1; cyclin box found in retinoblastoma-like protein 1 (RBL1) and similar proteins

  5. XM_038572247.1 → XP_038428175.1  retinoblastoma-like protein 1 isoform X6

    Conserved Domains (3) summary
    pfam01858
    Location:1 → 155
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:538 → 623
    Rb_C; Rb C-terminal domain
    cd20605
    Location:358 → 526
    CYCLIN_RBL1; cyclin box found in retinoblastoma-like protein 1 (RBL1) and similar proteins

  6. XM_038572246.1 → XP_038428174.1  retinoblastoma-like protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0KHC1
    Conserved Domains (3) summary
    pfam01858
    Location:385 → 578
    RB_A; Retinoblastoma-associated protein A domain
    pfam11934
    Location:77 → 209
    DUF3452; Domain of unknown function (DUF3452)
    cl40454
    Location:781 → 855
    CYCLIN_SF; Cyclin box fold superfamily

RNA

  1. XR_005377815.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006606.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    25346666..25405658 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038457784.1 → XP_038313712.1  retinoblastoma-like protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SKW5
    Conserved Domains (4) summary
    pfam01858
    Location:385 → 578
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:902 → 987
    Rb_C; Rb C-terminal domain
    pfam11934
    Location:77 → 209
    DUF3452; Domain of unknown function (DUF3452)
    cl40454
    Location:781 → 890
    CYCLIN_SF; Cyclin box fold superfamily

  2. XM_534412.7 → XP_534412.2  retinoblastoma-like protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QZQ2, A0A8C0SJ08, A0A8C0SKW5, A0A8I3Q0G8
    Conserved Domains (4) summary
    pfam01858
    Location:385 → 578
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:961 → 1046
    Rb_C; Rb C-terminal domain
    pfam11934
    Location:77 → 209
    DUF3452; Domain of unknown function (DUF3452)
    cd20605
    Location:781 → 949
    CYCLIN_RBL1; cyclin box found in retinoblastoma-like protein 1 (RBL1) and similar proteins

  3. XM_005635025.4 → XP_005635082.1  retinoblastoma-like protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0SKW5
    Conserved Domains (4) summary
    pfam01858
    Location:281 → 474
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:857 → 942
    Rb_C; Rb C-terminal domain
    pfam11934
    Location:1 → 105
    DUF3452; Domain of unknown function (DUF3452)
    cd20605
    Location:677 → 845
    CYCLIN_RBL1; cyclin box found in retinoblastoma-like protein 1 (RBL1) and similar proteins

  4. XM_005635024.4 → XP_005635081.1  retinoblastoma-like protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0SKW5
    Conserved Domains (4) summary
    pfam01858
    Location:306 → 499
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:882 → 967
    Rb_C; Rb C-terminal domain
    pfam11934
    Location:1 → 130
    DUF3452; Domain of unknown function (DUF3452)
    cd20605
    Location:702 → 870
    CYCLIN_RBL1; cyclin box found in retinoblastoma-like protein 1 (RBL1) and similar proteins

  5. XM_022409023.1 → XP_022264731.1  retinoblastoma-like protein 1 isoform X6

    Conserved Domains (3) summary
    pfam01858
    Location:1 → 155
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:538 → 623
    Rb_C; Rb C-terminal domain
    cd20605
    Location:358 → 526
    CYCLIN_RBL1; cyclin box found in retinoblastoma-like protein 1 (RBL1) and similar proteins

  6. XM_005635027.4 → XP_005635084.1  retinoblastoma-like protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0KHC1
    Conserved Domains (3) summary
    pfam01858
    Location:385 → 578
    RB_A; Retinoblastoma-associated protein A domain
    pfam11934
    Location:77 → 209
    DUF3452; Domain of unknown function (DUF3452)
    cl40454
    Location:781 → 855
    CYCLIN_SF; Cyclin box fold superfamily

RNA

  1. XR_002618530.2 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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