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MYLK2 myosin light chain kinase 2 [ Canis lupus familiaris (dog) ]

Gene ID: 477187, updated on 5-Mar-2024

Summary

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Official Symbol
MYLK2provided by VGNC
Official Full Name
myosin light chain kinase 2provided by VGNC
Primary source
VGNC:VGNC:43550
See related
Ensembl:ENSCAFG00845019293
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 24
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 24 NC_051828.1 (21971185..21984754)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 24 NC_006606.4 (20931709..20945281)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 24 NC_049245.1 (21785552..21799121)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 24 NC_049284.1 (21249626..21263199)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 24 NC_049765.1 (21354931..21368484)

Chromosome 24 - NC_051828.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106557730 Neighboring gene BCL2 like 1 Neighboring gene TPX2 microtubule nucleation factor Neighboring gene interferon regulatory factor 4-like Neighboring gene forkhead box S1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables myosin light chain kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
myosin light chain kinase 2, skeletal/cardiac muscle
Names
myosin light chain kinase 2, skeletal muscle
XP_005634973.1
XP_038289363.1
XP_038364567.1
XP_038427857.1
XP_038492112.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051828.1 Reference ROS_Cfam_1.0

    Range
    21971185..21984754
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038433435.1 → XP_038289363.1  myosin light chain kinase 2, skeletal/cardiac muscle

    UniProtKB/TrEMBL
    A0A8C0MSG4, A0A8C0Z4A7, A0A8I3P9R3
    Related
    ENSCAFP00845026628.1, ENSCAFT00845034024.1
    Conserved Domains (1) summary
    cd14190
    Location:319 → 578
    STKc_MLCK2; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 2

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049284.1 Alternate UMICH_Zoey_3.1

    Range
    21249626..21263199
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038508639.1 → XP_038364567.1  myosin light chain kinase 2, skeletal/cardiac muscle

    Conserved Domains (1) summary
    cd14190
    Location:319 → 578
    STKc_MLCK2; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 2

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049765.1 Alternate UNSW_CanFamBas_1.0

    Range
    21354931..21368484
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038636184.1 → XP_038492112.1  myosin light chain kinase 2, skeletal/cardiac muscle

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049245.1 Alternate UU_Cfam_GSD_1.0

    Range
    21785552..21799121
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038571929.1 → XP_038427857.1  myosin light chain kinase 2, skeletal/cardiac muscle

    UniProtKB/TrEMBL
    A0A8C0MSG4, A0A8C0N1Q3

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006606.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    20931709..20945281
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005634916.4 → XP_005634973.1  myosin light chain kinase 2, skeletal/cardiac muscle

    UniProtKB/TrEMBL
    A0A8C0MSG4, A0A8C0Z4A7, A0A8I3P9R3
    Conserved Domains (1) summary
    cd14190
    Location:319 → 578
    STKc_MLCK2; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 2
Nucleotide Protein
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