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DSTN destrin, actin depolymerizing factor [ Canis lupus familiaris (dog) ]

Gene ID: 477147, updated on 5-Mar-2024

Summary

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Official Symbol
DSTNprovided by VGNC
Official Full Name
destrin, actin depolymerizing factorprovided by VGNC
Primary source
VGNC:VGNC:40111
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 24
Exon count:
4
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 24 NC_051828.1 (5803229..5840053, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 24 NC_006606.4 (5327813..5364670, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 24 NC_049245.1 (5786183..5822988, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 24 NC_049284.1 (5416513..5453319, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 24 NC_049765.1 (5510480..5547273, complement)

Chromosome 24 - NC_051828.1Genomic Context describing neighboring genes Neighboring gene BANF family member 2 Neighboring gene ribosome binding protein 1 Neighboring gene 60S ribosomal protein L39-like Neighboring gene beaded filament structural protein 1 Neighboring gene proprotein convertase subtilisin/kexin type 2 Neighboring gene uncharacterized LOC111092048

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin filament fragmentation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in actin filament severing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell motility IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in actin cortical patch IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
destrin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051828.1 Reference ROS_Cfam_1.0

    Range
    5803229..5840053 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038433072.1 → XP_038289000.1  destrin

    UniProtKB/TrEMBL
    A0A8C0PHL7
    Conserved Domains (1) summary
    cd11286
    Location:3 → 152
    ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049284.1 Alternate UMICH_Zoey_3.1

    Range
    5416513..5453319 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038508284.1 → XP_038364212.1  destrin

    Conserved Domains (1) summary
    cd11286
    Location:3 → 152
    ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049765.1 Alternate UNSW_CanFamBas_1.0

    Range
    5510480..5547273 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038635782.1 → XP_038491710.1  destrin

    Conserved Domains (1) summary
    cd11286
    Location:3 → 152
    ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049245.1 Alternate UU_Cfam_GSD_1.0

    Range
    5786183..5822988 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038571540.1 → XP_038427468.1  destrin

    UniProtKB/TrEMBL
    A0A8C0PHL7
    Conserved Domains (1) summary
    cd11286
    Location:3 → 152
    ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006606.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    5327813..5364670 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038457503.1 → XP_038313431.1  destrin

    UniProtKB/TrEMBL
    A0A8C0PHL7
    Conserved Domains (1) summary
    cd11286
    Location:3 → 152
    ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors
Nucleotide Protein
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