U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ILK integrin linked kinase [ Canis lupus familiaris (dog) ]

Gene ID: 476836, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
ILKprovided by VGNC
Official Full Name
integrin linked kinaseprovided by VGNC
Primary source
VGNC:VGNC:42001
See related
Ensembl:ENSCAFG00845008689
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 21
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 21 NC_051825.1 (30737472..30744133)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 21 NC_006603.4 (29613150..29619814)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 21 NC_049242.1 (30419226..30425893)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 21 NC_049281.1 (30058249..30064907)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 21 NC_049762.1 (30223907..30230574)

Chromosome 21 - NC_051825.1Genomic Context describing neighboring genes Neighboring gene dynein heavy chain domain 1 Neighboring gene uncharacterized LOC119864994 Neighboring gene ribosomal RNA processing 8 Neighboring gene TATA-box binding protein associated factor 10 Neighboring gene tripeptidyl peptidase 1 Neighboring gene dachsous cadherin-related 1 Neighboring gene uncharacterized LOC111091544

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Integrin-linked kinase regulates smooth muscle differentiation marker gene expression in airway tissue. Wu Y, et al. Am J Physiol Lung Cell Mol Physiol, 2008 Dec. PMID 18805960, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in substrate adhesion-dependent cell spreading IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in stress fiber IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
integrin-linked protein kinase
XP_022263486.1
XP_038286300.1
XP_038286301.1
XP_038286302.1
XP_038286303.1
XP_038312258.1
XP_038312259.1
XP_038361628.1
XP_038361629.1
XP_038361630.1
XP_038361631.1
XP_038424837.1
XP_038424838.1
XP_038424839.1
XP_038424840.1
XP_038489002.1
XP_038489003.1
XP_038489004.1
XP_038489005.1
XP_534040.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051825.1 Reference ROS_Cfam_1.0

    Range
    30737472..30744133
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038430372.1 → XP_038286300.1  integrin-linked protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0KAB5, A0A8C0NE47, A0A8C0RXS6, A0A8I3N6J1
    Related
    ENSCAFP00845011870.1, ENSCAFT00845015287.1
    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_038430374.1 → XP_038286302.1  integrin-linked protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0KAB5, A0A8C0NE47, A0A8C0RXS6, A0A8I3N6J1
    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  3. XM_038430373.1 → XP_038286301.1  integrin-linked protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0KAB5, A0A8C0NE47, A0A8C0RXS6, A0A8I3N6J1
    Related
    ENSCAFP00845011903.1, ENSCAFT00845015333.1
    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_038430375.1 → XP_038286303.1  integrin-linked protein kinase isoform X2

    UniProtKB/TrEMBL
    A0A8C0NE47
    Conserved Domains (3) summary
    cd14057
    Location:171 → 422
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:6 → 37
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:11 → 97
    Ank_2; Ankyrin repeats (3 copies)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049281.1 Alternate UMICH_Zoey_3.1

    Range
    30058249..30064907
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038505700.1 → XP_038361628.1  integrin-linked protein kinase isoform X1

    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_038505702.1 → XP_038361630.1  integrin-linked protein kinase isoform X1

    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  3. XM_038505701.1 → XP_038361629.1  integrin-linked protein kinase isoform X1

    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_038505703.1 → XP_038361631.1  integrin-linked protein kinase isoform X2

    Conserved Domains (3) summary
    cd14057
    Location:171 → 422
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:6 → 37
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:11 → 97
    Ank_2; Ankyrin repeats (3 copies)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049762.1 Alternate UNSW_CanFamBas_1.0

    Range
    30223907..30230574
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038633074.1 → XP_038489002.1  integrin-linked protein kinase isoform X1

    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_038633076.1 → XP_038489004.1  integrin-linked protein kinase isoform X1

    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  3. XM_038633075.1 → XP_038489003.1  integrin-linked protein kinase isoform X1

    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_038633077.1 → XP_038489005.1  integrin-linked protein kinase isoform X2

    Conserved Domains (3) summary
    cd14057
    Location:171 → 422
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:6 → 37
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:11 → 97
    Ank_2; Ankyrin repeats (3 copies)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049242.1 Alternate UU_Cfam_GSD_1.0

    Range
    30419226..30425893
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038568909.1 → XP_038424837.1  integrin-linked protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0NE47, A0A8C0NGM4, A0A8P0TU48
    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_038568911.1 → XP_038424839.1  integrin-linked protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0NE47, A0A8C0NGM4, A0A8P0TU48
    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  3. XM_038568910.1 → XP_038424838.1  integrin-linked protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0NE47, A0A8C0NGM4, A0A8P0TU48
    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_038568912.1 → XP_038424840.1  integrin-linked protein kinase isoform X2

    UniProtKB/TrEMBL
    A0A8C0NE47
    Conserved Domains (3) summary
    cd14057
    Location:171 → 422
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:6 → 37
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:11 → 97
    Ank_2; Ankyrin repeats (3 copies)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006603.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    29613150..29619814
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_534040.7 → XP_534040.1  integrin-linked protein kinase isoform X1

    See identical proteins and their annotated locations for XP_534040.1

    UniProtKB/TrEMBL
    A0A8C0NE47, A0A8C0NGM4, A0A8P0TU48
    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_022407778.2 → XP_022263486.1  integrin-linked protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0NE47, A0A8C0NGM4, A0A8P0TU48
    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  3. XM_038456330.1 → XP_038312258.1  integrin-linked protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0NE47, A0A8C0NGM4, A0A8P0TU48
    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_038456331.1 → XP_038312259.1  integrin-linked protein kinase isoform X2

    UniProtKB/TrEMBL
    A0A8C0NE47
    Conserved Domains (3) summary
    cd14057
    Location:171 → 422
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:6 → 37
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:11 → 97
    Ank_2; Ankyrin repeats (3 copies)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous