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PDK1 pyruvate dehydrogenase kinase 1 [ Canis lupus familiaris (dog) ]

Gene ID: 476828, updated on 5-Mar-2024

Summary

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Official Symbol
PDK1provided by VGNC
Official Full Name
pyruvate dehydrogenase kinase 1provided by VGNC
Primary source
VGNC:VGNC:97211
See related
Ensembl:ENSCAFG00845028798
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 36
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 36 NC_051840.1 (17044728..17074152)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 36 NC_006618.4 (16924778..16954215)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 36 NC_049257.1 (17229734..17259496)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 36 NC_049296.1 (17126078..17155436)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 36 NC_049777.1 (17126377..17155712)

Chromosome 36 - NC_051840.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119867830 Neighboring gene integrin subunit alpha 6 Neighboring gene uncharacterized LOC102153619 Neighboring gene uncharacterized LOC111094204 Neighboring gene uncharacterized LOC119867831 Neighboring gene Rap guanine nucleotide exchange factor 4 Neighboring gene uncharacterized LOC102153088

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Polycystin-1 and Gα12 regulate the cleavage of E-cadherin in kidney epithelial cells. Xu JX, et al. Physiol Genomics, 2015 Feb. PMID 25492927, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables pyruvate dehydrogenase (acetyl-transferring) kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of glucose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial; LOW QUALITY PROTEIN: pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial; pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial
XP_038303010.1
XP_038303011.1
XP_038303012.1
XP_038319236.1
XP_038319237.1
XP_038377091.1
XP_038440790.1
XP_038440791.1
XP_038440792.1
XP_038505207.1
XP_038505208.1
XP_038505209.1
XP_534032.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051840.1 Reference ROS_Cfam_1.0

    Range
    17044728..17074152
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038447082.1 → XP_038303010.1  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0JUS9, A0A8C0N992, A0A8C0SA42, A0A8I3S6V6
    Related
    ENSCAFP00845039893.1, ENSCAFT00845050888.1
    Conserved Domains (2) summary
    cd16929
    Location:227 → 393
    HATPase_PDK-like; Histidine kinase-like ATPase domain of pyruvate dehydrogenase kinase, branched-chain alpha-ketoacid dehydrogenase kinase and related domains
    pfam10436
    Location:59 → 223
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

  2. XM_038447084.1 → XP_038303012.1  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8C0SA42
    Conserved Domains (2) summary
    pfam10436
    Location:59 → 223
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase
    cl00075
    Location:227 → 345
    HATPase; Histidine kinase-like ATPase domain

  3. XM_038447083.1 → XP_038303011.1  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0NA53
    Conserved Domains (2) summary
    cd16929
    Location:195 → 361
    HATPase_PDK-like; Histidine kinase-like ATPase domain of pyruvate dehydrogenase kinase, branched-chain alpha-ketoacid dehydrogenase kinase and related domains
    pfam10436
    Location:38 → 191
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049296.1 Alternate UMICH_Zoey_3.1

    Range
    17126078..17155436
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038521163.1 → XP_038377091.1  LOW QUALITY PROTEIN: pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049777.1 Alternate UNSW_CanFamBas_1.0

    Range
    17126377..17155712
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038649279.1 → XP_038505207.1  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X1

    Conserved Domains (2) summary
    cd16929
    Location:227 → 393
    HATPase_PDK-like; Histidine kinase-like ATPase domain of pyruvate dehydrogenase kinase, branched-chain alpha-ketoacid dehydrogenase kinase and related domains
    pfam10436
    Location:59 → 223
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

  2. XM_038649281.1 → XP_038505209.1  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X3

    Conserved Domains (2) summary
    pfam10436
    Location:59 → 223
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase
    cl00075
    Location:227 → 345
    HATPase; Histidine kinase-like ATPase domain

  3. XM_038649280.1 → XP_038505208.1  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X2

    Conserved Domains (2) summary
    cd16929
    Location:195 → 361
    HATPase_PDK-like; Histidine kinase-like ATPase domain of pyruvate dehydrogenase kinase, branched-chain alpha-ketoacid dehydrogenase kinase and related domains
    pfam10436
    Location:38 → 191
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049257.1 Alternate UU_Cfam_GSD_1.0

    Range
    17229734..17259496
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038584862.1 → XP_038440790.1  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0SA42, A0A8P0SHX6
    Conserved Domains (2) summary
    cd16929
    Location:227 → 393
    HATPase_PDK-like; Histidine kinase-like ATPase domain of pyruvate dehydrogenase kinase, branched-chain alpha-ketoacid dehydrogenase kinase and related domains
    pfam10436
    Location:59 → 223
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

  2. XM_038584864.1 → XP_038440792.1  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8C0SA42
    Conserved Domains (2) summary
    pfam10436
    Location:59 → 223
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase
    cl00075
    Location:227 → 345
    HATPase; Histidine kinase-like ATPase domain

  3. XM_038584863.1 → XP_038440791.1  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0NA53
    Conserved Domains (2) summary
    cd16929
    Location:195 → 361
    HATPase_PDK-like; Histidine kinase-like ATPase domain of pyruvate dehydrogenase kinase, branched-chain alpha-ketoacid dehydrogenase kinase and related domains
    pfam10436
    Location:38 → 191
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006618.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    16924778..16954215
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038463308.1 → XP_038319236.1  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0SA42, A0A8P0SHX6
    Conserved Domains (2) summary
    cd16929
    Location:227 → 393
    HATPase_PDK-like; Histidine kinase-like ATPase domain of pyruvate dehydrogenase kinase, branched-chain alpha-ketoacid dehydrogenase kinase and related domains
    pfam10436
    Location:59 → 223
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

  2. XM_038463309.1 → XP_038319237.1  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8C0SA42
    Conserved Domains (2) summary
    pfam10436
    Location:59 → 223
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase
    cl00075
    Location:227 → 345
    HATPase; Histidine kinase-like ATPase domain

  3. XM_534032.7 → XP_534032.3  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0NA53
    Conserved Domains (2) summary
    cd16929
    Location:195 → 361
    HATPase_PDK-like; Histidine kinase-like ATPase domain of pyruvate dehydrogenase kinase, branched-chain alpha-ketoacid dehydrogenase kinase and related domains
    pfam10436
    Location:38 → 191
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase
Nucleotide Protein
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