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PSENEN presenilin enhancer, gamma-secretase subunit [ Canis lupus familiaris (dog) ]

Gene ID: 476479, updated on 5-Mar-2024

Summary

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Official Symbol
PSENENprovided by VGNC
Official Full Name
presenilin enhancer, gamma-secretase subunitprovided by VGNC
Primary source
VGNC:VGNC:53755
See related
Ensembl:ENSCAFG00845001404
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
4
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (117490131..117491420, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (116292416..116293705, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (117732508..117733796, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (117053507..117054796, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (116677128..116678417, complement)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene proline and serine rich 3 Neighboring gene heat shock protein family B (small) member 6 Neighboring gene lin-37 DREAM MuvB core complex component Neighboring gene U2 small nuclear RNA auxiliary factor 1 like 4 Neighboring gene IGF like family receptor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in Notch receptor processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of gamma-secretase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
gamma-secretase subunit PEN-2
Names
presenilin enhancer 2 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001284449.1 → NP_001271378.1  gamma-secretase subunit PEN-2

    See identical proteins and their annotated locations for NP_001271378.1

    Status: PROVISIONAL

    Source sequence(s)
    AB793325
    UniProtKB/TrEMBL
    A0A8C0L1E4, A0A8C0MHU8, J9P0J9
    Related
    ENSCAFP00845001909.1, ENSCAFT00845002402.1
    Conserved Domains (1) summary
    pfam10251
    Location:7 → 99
    PEN-2; Presenilin enhancer-2 subunit of gamma secretase

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    117490131..117491420 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    117053507..117054796 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    116677128..116678417 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    117732508..117733796 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    116292416..116293705 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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