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PRMT1 protein arginine methyltransferase 1 [ Canis lupus familiaris (dog) ]

Gene ID: 476411, updated on 5-Mar-2024

Summary

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Official Symbol
PRMT1provided by VGNC
Official Full Name
protein arginine methyltransferase 1provided by VGNC
Primary source
VGNC:VGNC:44995
See related
Ensembl:ENSCAFG00845022617
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (107371449..107381481, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (106433570..106443601, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (107526251..107536278, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (107043700..107053728, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (106685774..106695794, complement)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene carnitine palmitoyltransferase 1C Neighboring gene adrenomedullin 5 (putative) Neighboring gene U4 spliceosomal RNA Neighboring gene BCL2 like 12

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Variance of DDAH/PRMT/ADMA pathway in atrial fibrillation dogs. Liu H, et al. Biochem Biophys Res Commun, 2008 Dec 19. PMID 18951871

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein-arginine N-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein arginine N-methyltransferase 1
XP_005616362.1
XP_005616363.1
XP_038323430.1
XP_038323431.1
XP_038323432.1
XP_038323433.1
XP_038384135.1
XP_038384137.1
XP_038384138.1
XP_038384139.1
XP_038448430.1
XP_038448431.1
XP_038448432.1
XP_038448433.1
XP_038512221.1
XP_038512222.1
XP_038512223.1
XP_038512224.1
XP_533615.2
XP_851543.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    107371449..107381481 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038656294.1 → XP_038512222.1  protein arginine N-methyltransferase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LFV5, A0A8C0LLB8, A0A8C0YZY6, A0A8I3PC81
    Related
    ENSCAFP00845031521.1, ENSCAFT00845040242.1
    Conserved Domains (1) summary
    cd02440
    Location:74 → 174
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  2. XM_038656293.1 → XP_038512221.1  protein arginine N-methyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LFV5, A0A8C0LKE2, A0A8C0LXV1, A0A8I3PS34
    Related
    ENSCAFP00845031439.1, ENSCAFT00845040142.1
    Conserved Domains (1) summary
    cd02440
    Location:92 → 192
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  3. XM_038656296.1 → XP_038512224.1  protein arginine N-methyltransferase 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LFV5, A0A8C0LVT8
    Conserved Domains (1) summary
    cd02440
    Location:63 → 163
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  4. XM_038656295.1 → XP_038512223.1  protein arginine N-methyltransferase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LFV5, A0A8C0LQ17, A0A8C0SVZ4, A0A8I3PGX5
    Related
    ENSCAFP00845031626.1, ENSCAFT00845040389.1
    Conserved Domains (1) summary
    cd02440
    Location:68 → 168
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    107043700..107053728 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038467503.1 → XP_038323431.1  protein arginine N-methyltransferase 1 isoform X2

    Conserved Domains (1) summary
    cd02440
    Location:74 → 174
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  2. XM_038467502.1 → XP_038323430.1  protein arginine N-methyltransferase 1 isoform X1

    Conserved Domains (1) summary
    cd02440
    Location:92 → 192
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  3. XM_038467505.1 → XP_038323433.1  protein arginine N-methyltransferase 1 isoform X4

    Conserved Domains (1) summary
    cd02440
    Location:63 → 163
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  4. XM_038467504.1 → XP_038323432.1  protein arginine N-methyltransferase 1 isoform X3

    Conserved Domains (1) summary
    cd02440
    Location:68 → 168
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    106685774..106695794 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038592503.1 → XP_038448431.1  protein arginine N-methyltransferase 1 isoform X2

    Conserved Domains (1) summary
    cd02440
    Location:74 → 174
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  2. XM_038592502.1 → XP_038448430.1  protein arginine N-methyltransferase 1 isoform X1

    Conserved Domains (1) summary
    cd02440
    Location:92 → 192
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  3. XM_038592505.1 → XP_038448433.1  protein arginine N-methyltransferase 1 isoform X4

    Conserved Domains (1) summary
    cd02440
    Location:63 → 163
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  4. XM_038592504.1 → XP_038448432.1  protein arginine N-methyltransferase 1 isoform X3

    Conserved Domains (1) summary
    cd02440
    Location:68 → 168
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    107526251..107536278 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038528209.1 → XP_038384137.1  protein arginine N-methyltransferase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LFV5, A0A8C0LLB8, A0A8C0YZY6, A0A8I3PC81
    Conserved Domains (1) summary
    cd02440
    Location:74 → 174
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  2. XM_038528207.1 → XP_038384135.1  protein arginine N-methyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LFV5, A0A8C0LKE2, A0A8C0LXV1, A0A8I3PS34
    Conserved Domains (1) summary
    cd02440
    Location:92 → 192
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  3. XM_038528211.1 → XP_038384139.1  protein arginine N-methyltransferase 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LFV5, A0A8C0LVT8
    Conserved Domains (1) summary
    cd02440
    Location:63 → 163
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  4. XM_038528210.1 → XP_038384138.1  protein arginine N-methyltransferase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LFV5, A0A8C0LQ17, A0A8C0SVZ4, A0A8I3PGX5
    Conserved Domains (1) summary
    cd02440
    Location:68 → 168
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    106433570..106443601 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_533615.7 → XP_533615.2  protein arginine N-methyltransferase 1 isoform X2

    See identical proteins and their annotated locations for XP_533615.2

    UniProtKB/TrEMBL
    A0A8C0LFV5, A0A8C0LLB8, A0A8C0YZY6, A0A8I3PC81
    Conserved Domains (1) summary
    cd02440
    Location:74 → 174
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  2. XM_846450.6 → XP_851543.1  protein arginine N-methyltransferase 1 isoform X1

    See identical proteins and their annotated locations for XP_851543.1

    UniProtKB/TrEMBL
    A0A8C0LFV5, A0A8C0LKE2, A0A8C0LXV1, A0A8I3PS34
    Conserved Domains (1) summary
    cd02440
    Location:92 → 192
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  3. XM_005616306.4 → XP_005616363.1  protein arginine N-methyltransferase 1 isoform X4

    See identical proteins and their annotated locations for XP_005616363.1

    UniProtKB/TrEMBL
    A0A8C0LFV5, A0A8C0LVT8
    Conserved Domains (1) summary
    cd02440
    Location:63 → 163
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  4. XM_005616305.4 → XP_005616362.1  protein arginine N-methyltransferase 1 isoform X3

    See identical proteins and their annotated locations for XP_005616362.1

    UniProtKB/TrEMBL
    A0A8C0LFV5, A0A8C0LQ17, A0A8C0SVZ4, A0A8I3PGX5
    Conserved Domains (1) summary
    cd02440
    Location:68 → 168
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
Nucleotide Protein
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