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AKAP12 A-kinase anchoring protein 12 [ Canis lupus familiaris (dog) ]

Gene ID: 476246, updated on 5-Mar-2024

Summary

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Official Symbol
AKAP12provided by VGNC
Official Full Name
A-kinase anchoring protein 12provided by VGNC
Primary source
VGNC:VGNC:37754
See related
Ensembl:ENSCAFG00845021174
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
6
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (41799868..41897347)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (42456089..42553626)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (42023588..42121300)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (41673111..41770835)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (41517208..41614636)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene pleckstrin homology and RhoGEF domain containing G1 Neighboring gene uncharacterized LOC119870751 Neighboring gene methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like Neighboring gene uncharacterized LOC111095761 Neighboring gene uncharacterized LOC119870752 Neighboring gene U4 spliceosomal RNA Neighboring gene zinc finger and BTB domain containing 2 Neighboring gene required for meiotic nuclear division 1 homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase A binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of protein kinase A signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of protein kinase C signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
A-kinase anchor protein 12
Names
A kinase (PRKA) anchor protein (gravin) 12

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    41799868..41897347
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038654444.1 → XP_038510372.1  A-kinase anchor protein 12 isoform X3

    UniProtKB/TrEMBL
    A0A8C0MW20
    Related
    ENSCAFP00845029278.1, ENSCAFT00845037374.1
    Conserved Domains (4) summary
    PTZ00121
    Location:206 → 854
    PTZ00121; MAEBL; Provisional
    PRK10811
    Location:1284 → 1469
    rne; ribonuclease E; Reviewed
    pfam03832
    Location:576 → 604
    WSK; WSK motif
    NF033875
    Location:1459 → 1672
    Agg_substance; LPXTG-anchored aggregation substance

  2. XM_038654443.1 → XP_038510371.1  A-kinase anchor protein 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0N3A3, A0A8I3PFX0
    Related
    ENSCAFP00845029355.1, ENSCAFT00845037466.1
    Conserved Domains (4) summary
    PTZ00121
    Location:122 → 770
    PTZ00121; MAEBL; Provisional
    PRK10811
    Location:1200 → 1385
    rne; ribonuclease E; Reviewed
    pfam03832
    Location:492 → 520
    WSK; WSK motif
    NF033875
    Location:1375 → 1588
    Agg_substance; LPXTG-anchored aggregation substance

  3. XM_038654442.1 → XP_038510370.1  A-kinase anchor protein 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RHL5, A0A8I3PKE6
    Related
    ENSCAFP00845029374.1, ENSCAFT00845037491.1
    Conserved Domains (4) summary
    PTZ00121
    Location:122 → 770
    PTZ00121; MAEBL; Provisional
    PRK10811
    Location:1200 → 1385
    rne; ribonuclease E; Reviewed
    pfam03832
    Location:492 → 520
    WSK; WSK motif
    NF033875
    Location:1375 → 1588
    Agg_substance; LPXTG-anchored aggregation substance

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    41673111..41770835
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038465679.1 → XP_038321607.1  A-kinase anchor protein 12 isoform X3

  2. XM_038465678.1 → XP_038321606.1  A-kinase anchor protein 12 isoform X2

  3. XM_038465677.1 → XP_038321605.1  A-kinase anchor protein 12 isoform X1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    41517208..41614636
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038590629.1 → XP_038446557.1  A-kinase anchor protein 12 isoform X3

  2. XM_038590631.1 → XP_038446559.1  A-kinase anchor protein 12 isoform X2

  3. XM_038590630.1 → XP_038446558.1  A-kinase anchor protein 12 isoform X1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    42023588..42121300
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038526325.1 → XP_038382253.1  A-kinase anchor protein 12 isoform X3

    UniProtKB/TrEMBL
    A0A8C0MW20

  2. XM_038526327.1 → XP_038382255.1  A-kinase anchor protein 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0N3A3

  3. XM_038526326.1 → XP_038382254.1  A-kinase anchor protein 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RHL5

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    42456089..42553626
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_533451.7 → XP_533451.2  A-kinase anchor protein 12 isoform X3

    UniProtKB/TrEMBL
    A0A8C0MW20, A0A8C0STI4
    Conserved Domains (1) summary
    pfam03832
    Location:577 → 604
    WSK; WSK motif

  2. XM_005615512.4 → XP_005615569.1  A-kinase anchor protein 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0N3A3, A0A8C0SUQ5
    Conserved Domains (1) summary
    pfam03832
    Location:493 → 520
    WSK; WSK motif

  3. XM_005615511.4 → XP_005615568.1  A-kinase anchor protein 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RHL5, A0A8C0STP0, A0A8P0N3R0
    Conserved Domains (1) summary
    pfam03832
    Location:493 → 520
    WSK; WSK motif
Nucleotide Protein
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