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ERCC3 ERCC excision repair 3, TFIIH core complex helicase subunit [ Canis lupus familiaris (dog) ]

Gene ID: 476105, updated on 5-Mar-2024

Summary

Official Symbol
ERCC3provided by VGNC
Official Full Name
ERCC excision repair 3, TFIIH core complex helicase subunitprovided by VGNC
Primary source
VGNC:VGNC:40443
See related
Ensembl:ENSCAFG00845022679
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: 19
Exon count:
17
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 19 NC_051823.1 (24637517..24670735)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 19 NC_006601.4 (23558376..23591562)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 19 NC_049240.1 (24667951..24701129)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 19 NC_049279.1 (23341076..23374276)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 19 NC_049760.1 (23536737..23569970)

Chromosome 19 - NC_051823.1Genomic Context describing neighboring genes Neighboring gene malate dehydrogenase, mitochondrial-like Neighboring gene mitogen-activated protein kinase kinase kinase 2 Neighboring gene uncharacterized LOC119864468 Neighboring gene cytochrome P450 family 27 subfamily C member 1

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3'-5' DNA helicase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in embryonic organ development IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in hair cell differentiation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in nucleotide-excision repair IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in transcription initiation at RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of nucleotide-excision repair factor 3 complex IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of transcription factor TFIIH holo complex IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of transcription preinitiation complex IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
TFIIH basal transcription factor complex helicase XPB subunit; general transcription and DNA repair factor IIH helicase subunit XPB
Names
excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)
XP_005631937.1
XP_005631938.1
XP_005631939.1
XP_005631940.1
XP_038281885.1
XP_038281886.1
XP_038281887.1
XP_038281888.1
XP_038358092.1
XP_038358093.1
XP_038358094.1
XP_038358095.1
XP_038420782.1
XP_038420783.1
XP_038420784.1
XP_038420785.1
XP_038484878.1
XP_038484879.1
XP_038484880.1
XP_038484881.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051823.1 Reference ROS_Cfam_1.0

    Range
    24637517..24670735
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038425960.1XP_038281888.1  general transcription and DNA repair factor IIH helicase subunit XPB

    UniProtKB/TrEMBL
    A0A8C0JQP7, A0A8C0MF29, A0A8C0MGQ3, A0A8I3PKW9
    Related
    ENSCAFP00845031448.1, ENSCAFT00845040151.1
    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25
  2. XM_038425958.1XP_038281886.1  general transcription and DNA repair factor IIH helicase subunit XPB

    UniProtKB/TrEMBL
    A0A8C0JQP7, A0A8C0MF29, A0A8C0MGQ3, A0A8I3PKW9
    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25
  3. XM_038425959.1XP_038281887.1  general transcription and DNA repair factor IIH helicase subunit XPB

    UniProtKB/TrEMBL
    A0A8C0JQP7, A0A8C0MF29, A0A8C0MGQ3, A0A8I3PKW9
    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25
  4. XM_038425957.1XP_038281885.1  general transcription and DNA repair factor IIH helicase subunit XPB

    UniProtKB/TrEMBL
    A0A8C0JQP7, A0A8C0MF29, A0A8C0MGQ3, A0A8I3PKW9
    Related
    ENSCAFP00845031351.1, ENSCAFT00845040037.1
    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25

RNA

  1. XR_005297074.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049279.1 Alternate UMICH_Zoey_3.1

    Range
    23341076..23374276
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038502167.1XP_038358095.1  general transcription and DNA repair factor IIH helicase subunit XPB

    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25
  2. XM_038502165.1XP_038358093.1  general transcription and DNA repair factor IIH helicase subunit XPB

    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25
  3. XM_038502166.1XP_038358094.1  general transcription and DNA repair factor IIH helicase subunit XPB

    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25
  4. XM_038502164.1XP_038358092.1  general transcription and DNA repair factor IIH helicase subunit XPB

    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25

RNA

  1. XR_005340264.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049760.1 Alternate UNSW_CanFamBas_1.0

    Range
    23536737..23569970
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038628953.1XP_038484881.1  general transcription and DNA repair factor IIH helicase subunit XPB

    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25
  2. XM_038628951.1XP_038484879.1  general transcription and DNA repair factor IIH helicase subunit XPB

    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25
  3. XM_038628952.1XP_038484880.1  general transcription and DNA repair factor IIH helicase subunit XPB

    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25
  4. XM_038628950.1XP_038484878.1  general transcription and DNA repair factor IIH helicase subunit XPB

    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25

RNA

  1. XR_005408075.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049240.1 Alternate UU_Cfam_GSD_1.0

    Range
    24667951..24701129
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038564857.1XP_038420785.1  general transcription and DNA repair factor IIH helicase subunit XPB

    UniProtKB/TrEMBL
    A0A8C0JQP7, A0A8C0MF29, A0A8C0MGQ3, A0A8I3PKW9
    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25
  2. XM_038564855.1XP_038420783.1  general transcription and DNA repair factor IIH helicase subunit XPB

    UniProtKB/TrEMBL
    A0A8C0JQP7, A0A8C0MF29, A0A8C0MGQ3, A0A8I3PKW9
    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25
  3. XM_038564856.1XP_038420784.1  general transcription and DNA repair factor IIH helicase subunit XPB

    UniProtKB/TrEMBL
    A0A8C0JQP7, A0A8C0MF29, A0A8C0MGQ3, A0A8I3PKW9
    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25
  4. XM_038564854.1XP_038420782.1  general transcription and DNA repair factor IIH helicase subunit XPB

    UniProtKB/TrEMBL
    A0A8C0JQP7, A0A8C0MF29, A0A8C0MGQ3, A0A8I3PKW9
    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25

RNA

  1. XR_005374038.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006601.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    23558376..23591562
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005631881.4XP_005631938.1  general transcription and DNA repair factor IIH helicase subunit XPB

    See identical proteins and their annotated locations for XP_005631938.1

    UniProtKB/TrEMBL
    A0A8C0JQP7, A0A8C0MF29, A0A8C0MGQ3, A0A8I3PKW9
    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25
  2. XM_005631882.4XP_005631939.1  general transcription and DNA repair factor IIH helicase subunit XPB

    See identical proteins and their annotated locations for XP_005631939.1

    UniProtKB/TrEMBL
    A0A8C0JQP7, A0A8C0MF29, A0A8C0MGQ3, A0A8I3PKW9
    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25
  3. XM_005631883.4XP_005631940.1  general transcription and DNA repair factor IIH helicase subunit XPB

    See identical proteins and their annotated locations for XP_005631940.1

    UniProtKB/TrEMBL
    A0A8C0JQP7, A0A8C0MF29, A0A8C0MGQ3, A0A8I3PKW9
    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25
  4. XM_005631880.4XP_005631937.1  general transcription and DNA repair factor IIH helicase subunit XPB

    See identical proteins and their annotated locations for XP_005631937.1

    UniProtKB/TrEMBL
    A0A8C0JQP7, A0A8C0MF29, A0A8C0MGQ3, A0A8I3PKW9
    Conserved Domains (1) summary
    TIGR00603
    Location:57776
    rad25; DNA repair helicase rad25

RNA

  1. XR_002616278.2 RNA Sequence