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POLR1A RNA polymerase I subunit A [ Canis lupus familiaris (dog) ]

Gene ID: 475766, updated on 5-Mar-2024

Summary

Official Symbol
POLR1Aprovided by VGNC
Official Full Name
RNA polymerase I subunit Aprovided by VGNC
Primary source
VGNC:VGNC:44788
See related
Ensembl:ENSCAFG00845013628
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: 17
Exon count:
35
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 17 NC_051821.1 (39722717..39805020)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 17 NC_006599.4 (38675191..38756338)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 17 NC_049238.1 (39313308..39394902)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 17 NC_049277.1 (38891244..38972175)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 17 NC_049758.1 (38927011..39009075)

Chromosome 17 - NC_051821.1Genomic Context describing neighboring genes Neighboring gene inner membrane mitochondrial protein Neighboring gene small nucleolar RNA SNORD94 Neighboring gene pentatricopeptide repeat domain 3 Neighboring gene histone H3.v1-like Neighboring gene uncharacterized LOC102156388 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables DNA-directed 5'-3' RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of RNA polymerase I complex IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
DNA-directed RNA polymerase I subunit RPA1
Names
polymerase (RNA) I polypeptide A, 194kDa
XP_038308997.1
XP_038354876.1
XP_038354877.1
XP_038417462.1
XP_038417463.1
XP_038481505.1
XP_038481506.1
XP_038547427.1
XP_038547428.1
XP_532976.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051821.1 Reference ROS_Cfam_1.0

    Range
    39722717..39805020
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038691500.1XP_038547428.1  DNA-directed RNA polymerase I subunit RPA1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KTK8
    Conserved Domains (2) summary
    cd01435
    Location:166896
    RNAP_I_RPA1_N; Largest subunit (RPA1) of eukaryotic RNA polymerase I (RNAP I), N-terminal domain
    pfam04998
    Location:8501559
    RNA_pol_Rpb1_5; RNA polymerase Rpb1, domain 5
  2. XM_038691499.1XP_038547427.1  DNA-directed RNA polymerase I subunit RPA1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KTK8, A0A8C0Z124, A0A8I3NGT8
    Related
    ENSCAFP00845019163.1, ENSCAFT00845024381.1
    Conserved Domains (2) summary
    cd01435
    Location:161004
    RNAP_I_RPA1_N; Largest subunit (RPA1) of eukaryotic RNA polymerase I (RNAP I), N-terminal domain
    pfam04998
    Location:9581667
    RNA_pol_Rpb1_5; RNA polymerase Rpb1, domain 5

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049277.1 Alternate UMICH_Zoey_3.1

    Range
    38891244..38972175
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038498949.1XP_038354877.1  DNA-directed RNA polymerase I subunit RPA1 isoform X2

    Conserved Domains (2) summary
    cd01435
    Location:166896
    RNAP_I_RPA1_N; Largest subunit (RPA1) of eukaryotic RNA polymerase I (RNAP I), N-terminal domain
    pfam04998
    Location:8501559
    RNA_pol_Rpb1_5; RNA polymerase Rpb1, domain 5
  2. XM_038498948.1XP_038354876.1  DNA-directed RNA polymerase I subunit RPA1 isoform X1

    Conserved Domains (2) summary
    cd01435
    Location:161004
    RNAP_I_RPA1_N; Largest subunit (RPA1) of eukaryotic RNA polymerase I (RNAP I), N-terminal domain
    pfam04998
    Location:9581667
    RNA_pol_Rpb1_5; RNA polymerase Rpb1, domain 5

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049758.1 Alternate UNSW_CanFamBas_1.0

    Range
    38927011..39009075
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038625578.1XP_038481506.1  DNA-directed RNA polymerase I subunit RPA1 isoform X2

  2. XM_038625577.1XP_038481505.1  DNA-directed RNA polymerase I subunit RPA1 isoform X1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049238.1 Alternate UU_Cfam_GSD_1.0

    Range
    39313308..39394902
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038561535.1XP_038417463.1  DNA-directed RNA polymerase I subunit RPA1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KTK8
    Conserved Domains (2) summary
    cd01435
    Location:166896
    RNAP_I_RPA1_N; Largest subunit (RPA1) of eukaryotic RNA polymerase I (RNAP I), N-terminal domain
    pfam04998
    Location:8501559
    RNA_pol_Rpb1_5; RNA polymerase Rpb1, domain 5
  2. XM_038561534.1XP_038417462.1  DNA-directed RNA polymerase I subunit RPA1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KTK8, A0A8C0Z124, A0A8I3NGT8
    Conserved Domains (2) summary
    cd01435
    Location:161004
    RNAP_I_RPA1_N; Largest subunit (RPA1) of eukaryotic RNA polymerase I (RNAP I), N-terminal domain
    pfam04998
    Location:9581667
    RNA_pol_Rpb1_5; RNA polymerase Rpb1, domain 5

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    38675191..38756338
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038453069.1XP_038308997.1  DNA-directed RNA polymerase I subunit RPA1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KTK8
    Conserved Domains (2) summary
    cd01435
    Location:166896
    RNAP_I_RPA1_N; Largest subunit (RPA1) of eukaryotic RNA polymerase I (RNAP I), N-terminal domain
    pfam04998
    Location:8501559
    RNA_pol_Rpb1_5; RNA polymerase Rpb1, domain 5
  2. XM_532976.6XP_532976.3  DNA-directed RNA polymerase I subunit RPA1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KTK8, A0A8C0Z124, A0A8I3NGT8
    Conserved Domains (2) summary
    cd01435
    Location:161004
    RNAP_I_RPA1_N; Largest subunit (RPA1) of eukaryotic RNA polymerase I (RNAP I), N-terminal domain
    pfam04998
    Location:9581667
    RNA_pol_Rpb1_5; RNA polymerase Rpb1, domain 5