U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

EPS15 epidermal growth factor receptor pathway substrate 15 [ Canis lupus familiaris (dog) ]

Gene ID: 475356, updated on 5-Mar-2024

Summary

Official Symbol
EPS15provided by VGNC
Official Full Name
epidermal growth factor receptor pathway substrate 15provided by VGNC
Primary source
VGNC:VGNC:54202
See related
Ensembl:ENSCAFG00845022599
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
chromosome: 15
Exon count:
25
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (9877844..10020742)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (9904456..10047227)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 15 NC_049236.1 (9794994..9938012)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (9689665..9832450)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 15 NC_049756.1 (9778543..9921371)

Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene nardilysin convertase Neighboring gene microRNA mir-761 Neighboring gene small nucleolar RNA U3 Neighboring gene oxysterol binding protein like 9 Neighboring gene calmodulin-like Neighboring gene U4 spliceosomal RNA Neighboring gene tetratricopeptide repeat domain 39A Neighboring gene uncharacterized LOC111098970 Neighboring gene ring finger protein 11

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cadherin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in endocytosis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in endosomal transport IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of clathrin coat of coated pit IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
epidermal growth factor receptor substrate 15

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051819.1 Reference ROS_Cfam_1.0

    Range
    9877844..10020742
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038687684.1XP_038543612.1  epidermal growth factor receptor substrate 15 isoform X4

    UniProtKB/TrEMBL
    A0A8I3PMU1, A0A8P0S9I1
    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:370544
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  2. XM_038687681.1XP_038543609.1  epidermal growth factor receptor substrate 15 isoform X1

    UniProtKB/TrEMBL
    A0A8C0N0M0, A0A8I3PMU1, A0A8P0S9I1
    Related
    ENSCAFP00845032135.1, ENSCAFT00845041017.1
    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:370544
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  3. XM_038687683.1XP_038543611.1  epidermal growth factor receptor substrate 15 isoform X3

    UniProtKB/TrEMBL
    A0A8C0RG23
    Related
    ENSCAFP00845031745.1, ENSCAFT00845040550.1
    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:370545
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  4. XM_038687682.1XP_038543610.1  epidermal growth factor receptor substrate 15 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KLW8, A0A8I3PJA6, A0A8I3PRJ4, A0A8P0PG63, A0A8P0TM49
    Related
    ENSCAFP00845031280.1, ENSCAFT00845039946.1
    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:333507
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049275.1 Alternate UMICH_Zoey_3.1

    Range
    9689665..9832450
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038495686.1XP_038351614.1  epidermal growth factor receptor substrate 15 isoform X4

    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:370544
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  2. XM_038495683.1XP_038351611.1  epidermal growth factor receptor substrate 15 isoform X1

    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:370544
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  3. XM_038495685.1XP_038351613.1  epidermal growth factor receptor substrate 15 isoform X3

    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:370545
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  4. XM_038495684.1XP_038351612.1  epidermal growth factor receptor substrate 15 isoform X2

    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:333507
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049756.1 Alternate UNSW_CanFamBas_1.0

    Range
    9778543..9921371
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038621926.1XP_038477854.1  epidermal growth factor receptor substrate 15 isoform X4

    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:370544
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  2. XM_038621922.1XP_038477850.1  epidermal growth factor receptor substrate 15 isoform X1

    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:370544
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  3. XM_038621925.1XP_038477853.1  epidermal growth factor receptor substrate 15 isoform X3

    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:370545
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  4. XM_038621923.1XP_038477851.1  epidermal growth factor receptor substrate 15 isoform X2

    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:333507
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049236.1 Alternate UU_Cfam_GSD_1.0

    Range
    9794994..9938012
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038558055.1XP_038413983.1  epidermal growth factor receptor substrate 15 isoform X4

    UniProtKB/TrEMBL
    A0A8I3PMU1, A0A8P0S9I1
    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:370544
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  2. XM_038558052.1XP_038413980.1  epidermal growth factor receptor substrate 15 isoform X1

    UniProtKB/TrEMBL
    A0A8C0N0M0, A0A8I3PMU1, A0A8P0S9I1
    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:370544
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  3. XM_038558054.1XP_038413982.1  epidermal growth factor receptor substrate 15 isoform X3

    UniProtKB/TrEMBL
    A0A8C0RG23
    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:370545
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  4. XM_038558053.1XP_038413981.1  epidermal growth factor receptor substrate 15 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KLW8, A0A8I3PJA6, A0A8I3PRJ4, A0A8P0PG63, A0A8P0TM49
    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:333507
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    9904456..10047227
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038448230.1XP_038304158.1  epidermal growth factor receptor substrate 15 isoform X4

    UniProtKB/TrEMBL
    A0A8I3PMU1, A0A8P0S9I1
    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:370544
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  2. XM_038448207.1XP_038304135.1  epidermal growth factor receptor substrate 15 isoform X1

    UniProtKB/TrEMBL
    A0A8C0N0M0, A0A8I3PMU1, A0A8P0S9I1
    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:370544
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  3. XM_038448219.1XP_038304147.1  epidermal growth factor receptor substrate 15 isoform X3

    UniProtKB/TrEMBL
    A0A8C0RG23
    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:370545
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  4. XM_038448214.1XP_038304142.1  epidermal growth factor receptor substrate 15 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KLW8, A0A8I3PJA6, A0A8I3PRJ4, A0A8P0PG63, A0A8P0TM49
    Conserved Domains (2) summary
    smart00027
    Location:121215
    EH; Eps15 homology domain
    COG1196
    Location:333507
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]