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ITGB8 integrin subunit beta 8 [ Canis lupus familiaris (dog) ]

Gene ID: 475253, updated on 5-Mar-2024

Summary

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Official Symbol
ITGB8provided by VGNC
Official Full Name
integrin subunit beta 8provided by VGNC
Primary source
VGNC:VGNC:42143
See related
Ensembl:ENSCAFG00845007494
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
18
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 14 NC_051818.1 (34291410..34369408)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 14 NC_006596.4 (33907455..33985373)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 14 NC_049235.1 (34421084..34499007)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 14 NC_049274.1 (34409582..34487497)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 14 NC_049755.1 (34110235..34188365)

Chromosome 14 - NC_051818.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L6-like Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC102155599 Neighboring gene uncharacterized LOC111098790 Neighboring gene alcohol dehydrogenase class-3-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
integrin beta-8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051818.1 Reference ROS_Cfam_1.0

    Range
    34291410..34369408
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038686695.1 → XP_038542623.1  integrin beta-8 isoform X3

    UniProtKB/TrEMBL
    A0A8C0Q8B1
    Conserved Domains (2) summary
    smart00187
    Location:18 → 432
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:419 → 606
    exchanger_TraA; outer membrane exchange protein TraA

  2. XM_038686693.1 → XP_038542621.1  integrin beta-8 isoform X1

    UniProtKB/TrEMBL
    A0A8C0P6P1, A0A8C0Q8B1, A0A8I3RVE5
    Related
    ENSCAFP00845010268.1, ENSCAFT00845013214.1
    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  3. XM_038686694.1 → XP_038542622.1  integrin beta-8 isoform X2

    UniProtKB/TrEMBL
    A0A8C0Q8B1
    Related
    ENSCAFP00845010318.1, ENSCAFT00845013294.1
    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  4. XM_038686696.1 → XP_038542624.1  integrin beta-8 isoform X4

    UniProtKB/TrEMBL
    A0A8I3N232, A0A8P0SWI9
    Related
    ENSCAFP00845010334.1, ENSCAFT00845013317.1
    Conserved Domains (2) summary
    NF033759
    Location:321 → 508
    exchanger_TraA; outer membrane exchange protein TraA
    cl00057
    Location:1 → 334
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049274.1 Alternate UMICH_Zoey_3.1

    Range
    34409582..34487497
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038494783.1 → XP_038350711.1  integrin beta-8 isoform X3

    Conserved Domains (2) summary
    smart00187
    Location:18 → 432
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:419 → 606
    exchanger_TraA; outer membrane exchange protein TraA

  2. XM_038494781.1 → XP_038350709.1  integrin beta-8 isoform X1

    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  3. XM_038494782.1 → XP_038350710.1  integrin beta-8 isoform X2

    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  4. XM_038494784.1 → XP_038350712.1  integrin beta-8 isoform X4

    Conserved Domains (2) summary
    NF033759
    Location:321 → 508
    exchanger_TraA; outer membrane exchange protein TraA
    cl00057
    Location:1 → 334
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049755.1 Alternate UNSW_CanFamBas_1.0

    Range
    34110235..34188365
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038621001.1 → XP_038476929.1  integrin beta-8 isoform X3

    Conserved Domains (2) summary
    smart00187
    Location:18 → 432
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:419 → 606
    exchanger_TraA; outer membrane exchange protein TraA

  2. XM_038621000.1 → XP_038476928.1  integrin beta-8 isoform X2

    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  3. XM_038620999.1 → XP_038476927.1  integrin beta-8 isoform X1

    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  4. XM_038621002.1 → XP_038476930.1  integrin beta-8 isoform X4

    Conserved Domains (2) summary
    NF033759
    Location:321 → 508
    exchanger_TraA; outer membrane exchange protein TraA
    cl00057
    Location:1 → 334
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049235.1 Alternate UU_Cfam_GSD_1.0

    Range
    34421084..34499007
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038557068.1 → XP_038412996.1  integrin beta-8 isoform X3

    UniProtKB/TrEMBL
    A0A8C0Q8B1
    Conserved Domains (2) summary
    smart00187
    Location:18 → 432
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:419 → 606
    exchanger_TraA; outer membrane exchange protein TraA

  2. XM_038557067.1 → XP_038412995.1  integrin beta-8 isoform X2

    UniProtKB/TrEMBL
    A0A8C0Q8B1
    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  3. XM_038557065.1 → XP_038412993.1  integrin beta-8 isoform X1

    UniProtKB/TrEMBL
    A0A8C0P6P1, A0A8C0Q8B1, A0A8I3RVE5
    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  4. XM_038557069.1 → XP_038412997.1  integrin beta-8 isoform X4

    UniProtKB/TrEMBL
    A0A8I3N232, A0A8P0SWI9
    Conserved Domains (2) summary
    NF033759
    Location:321 → 508
    exchanger_TraA; outer membrane exchange protein TraA
    cl00057
    Location:1 → 334
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006596.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    33907455..33985373
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038434587.1 → XP_038290515.1  integrin beta-8 isoform X3

    UniProtKB/TrEMBL
    A0A8C0Q8B1
    Conserved Domains (2) summary
    smart00187
    Location:18 → 432
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:419 → 606
    exchanger_TraA; outer membrane exchange protein TraA

  2. XM_038434579.1 → XP_038290507.1  integrin beta-8 isoform X1

    UniProtKB/TrEMBL
    A0A8C0P6P1, A0A8C0Q8B1, A0A8I3RVE5
    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  3. XM_532487.3 → XP_532487.1  integrin beta-8 isoform X2

    UniProtKB/TrEMBL
    A0A8C0Q8B1
    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  4. XM_038434593.1 → XP_038290521.1  integrin beta-8 isoform X4

    UniProtKB/TrEMBL
    A0A8I3N232, A0A8P0SWI9
    Conserved Domains (2) summary
    NF033759
    Location:321 → 508
    exchanger_TraA; outer membrane exchange protein TraA
    cl00057
    Location:1 → 334
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
Nucleotide Protein
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