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CYP51A1 cytochrome P450 family 51 subfamily A member 1 [ Canis lupus familiaris (dog) ]

Gene ID: 475225, updated on 5-Mar-2024

Summary

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Official Symbol
CYP51A1provided by VGNC
Official Full Name
cytochrome P450 family 51 subfamily A member 1provided by VGNC
Primary source
VGNC:VGNC:50376
See related
Ensembl:ENSCAFG00845012499
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
11
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 14 NC_051818.1 (17552569..17573808, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 14 NC_006596.4 (17307241..17328397, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 14 NC_049235.1 (17699282..17720469, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 14 NC_049274.1 (17710915..17732068, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 14 NC_049755.1 (17425396..17446546, complement)

Chromosome 14 - NC_051818.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100686051 Neighboring gene formin-like protein 5 Neighboring gene A-kinase anchoring protein 9 Neighboring gene ankyrin repeat and IBR domain containing 1 Neighboring gene mRNA turnover protein 4 homolog Neighboring gene leucine rich repeats and death domain containing 1 Neighboring gene RNA-binding protein EWS-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lanosterol 14-alpha demethylase
Names
cytochrome P450, family 51, subfamily A, polypeptide 1
XP_005628556.1
XP_022283046.1
XP_038350410.1
XP_038350411.1
XP_038350412.1
XP_038412704.1
XP_038412705.1
XP_038412706.1
XP_038476639.1
XP_038476640.1
XP_038476641.1
XP_038542324.1
XP_038542325.1
XP_038542326.1
XP_532457.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051818.1 Reference ROS_Cfam_1.0

    Range
    17552569..17573808 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038686397.1 → XP_038542325.1  lanosterol 14-alpha demethylase isoform X2

    Conserved Domains (1) summary
    cd11042
    Location:1 → 400
    CYP51-like; cytochrome P450 family 51 and similar cytochrome P450s

  2. XM_038686398.1 → XP_038542326.1  lanosterol 14-alpha demethylase isoform X2

    Conserved Domains (1) summary
    cd11042
    Location:1 → 400
    CYP51-like; cytochrome P450 family 51 and similar cytochrome P450s

  3. XM_038686396.1 → XP_038542324.1  lanosterol 14-alpha demethylase isoform X1

    UniProtKB/TrEMBL
    A0A8C0KHI8, A0A8C0Z2B7, A0A8I3NH11, A0A8P0N517
    Related
    ENSCAFP00845017507.1, ENSCAFT00845022260.1
    Conserved Domains (1) summary
    cd11042
    Location:88 → 499
    CYP51-like; cytochrome P450 family 51 and similar cytochrome P450s

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049274.1 Alternate UMICH_Zoey_3.1

    Range
    17710915..17732068 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038494483.1 → XP_038350411.1  lanosterol 14-alpha demethylase isoform X2

    Conserved Domains (1) summary
    cd11042
    Location:1 → 400
    CYP51-like; cytochrome P450 family 51 and similar cytochrome P450s

  2. XM_038494484.1 → XP_038350412.1  lanosterol 14-alpha demethylase isoform X2

    Conserved Domains (1) summary
    cd11042
    Location:1 → 400
    CYP51-like; cytochrome P450 family 51 and similar cytochrome P450s

  3. XM_038494482.1 → XP_038350410.1  lanosterol 14-alpha demethylase isoform X1

    Conserved Domains (1) summary
    cd11042
    Location:88 → 499
    CYP51-like; cytochrome P450 family 51 and similar cytochrome P450s

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049755.1 Alternate UNSW_CanFamBas_1.0

    Range
    17425396..17446546 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038620712.1 → XP_038476640.1  lanosterol 14-alpha demethylase isoform X2

    Conserved Domains (1) summary
    cd11042
    Location:1 → 400
    CYP51-like; cytochrome P450 family 51 and similar cytochrome P450s

  2. XM_038620713.1 → XP_038476641.1  lanosterol 14-alpha demethylase isoform X2

    Conserved Domains (1) summary
    cd11042
    Location:1 → 400
    CYP51-like; cytochrome P450 family 51 and similar cytochrome P450s

  3. XM_038620711.1 → XP_038476639.1  lanosterol 14-alpha demethylase isoform X1

    Conserved Domains (1) summary
    cd11042
    Location:88 → 499
    CYP51-like; cytochrome P450 family 51 and similar cytochrome P450s

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049235.1 Alternate UU_Cfam_GSD_1.0

    Range
    17699282..17720469 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038556777.1 → XP_038412705.1  lanosterol 14-alpha demethylase isoform X2

    Conserved Domains (1) summary
    cd11042
    Location:1 → 400
    CYP51-like; cytochrome P450 family 51 and similar cytochrome P450s

  2. XM_038556778.1 → XP_038412706.1  lanosterol 14-alpha demethylase isoform X2

    Conserved Domains (1) summary
    cd11042
    Location:1 → 400
    CYP51-like; cytochrome P450 family 51 and similar cytochrome P450s

  3. XM_038556776.1 → XP_038412704.1  lanosterol 14-alpha demethylase isoform X1

    UniProtKB/TrEMBL
    A0A8C0KHI8, A0A8C0Z2B7, A0A8I3NH11, A0A8P0N517
    Conserved Domains (1) summary
    cd11042
    Location:88 → 499
    CYP51-like; cytochrome P450 family 51 and similar cytochrome P450s

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006596.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    17307241..17328397 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005628499.4 → XP_005628556.1  lanosterol 14-alpha demethylase isoform X2

    Conserved Domains (1) summary
    cd11042
    Location:1 → 400
    CYP51-like; cytochrome P450 family 51 and similar cytochrome P450s

  2. XM_022427338.2 → XP_022283046.1  lanosterol 14-alpha demethylase isoform X2

    Conserved Domains (1) summary
    cd11042
    Location:1 → 400
    CYP51-like; cytochrome P450 family 51 and similar cytochrome P450s

  3. XM_532457.7 → XP_532457.3  lanosterol 14-alpha demethylase isoform X1

    UniProtKB/TrEMBL
    A0A8C0KHI8, A0A8C0Z2B7, A0A8I3NH11, A0A8P0N517
    Conserved Domains (1) summary
    cd11042
    Location:88 → 499
    CYP51-like; cytochrome P450 family 51 and similar cytochrome P450s
Nucleotide Protein
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