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WASL WASP like actin nucleation promoting factor [ Canis lupus familiaris (dog) ]

Gene ID: 475213, updated on 5-Mar-2024

Summary

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Official Symbol
WASLprovided by VGNC
Official Full Name
WASP like actin nucleation promoting factorprovided by VGNC
Primary source
VGNC:VGNC:58887
See related
Ensembl:ENSCAFG00845006059
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
13
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 14 NC_051818.1 (11605958..11678914)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 14 NC_006596.4 (11512373..11585271)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 14 NC_049235.1 (11774079..11846981)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 14 NC_049274.1 (11795524..11868439)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 14 NC_049755.1 (11533495..11606377)

Chromosome 14 - NC_051818.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U3 Neighboring gene uncharacterized LOC119874505 Neighboring gene uncharacterized LOC119866141 Neighboring gene uncharacterized LOC102157206 Neighboring gene leiomodin 2 Neighboring gene ankyrin repeat and SOCS box containing 15

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin filament organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neural Wiskott-Aldrich syndrome protein
Names
Wiskott-Aldrich syndrome like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051818.1 Reference ROS_Cfam_1.0

    Range
    11605958..11678914
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038686264.1 → XP_038542192.1  neural Wiskott-Aldrich syndrome protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0M4U7, A0A8C0R5D1, A0A8C0YTV2, A0A8I3MR53
    Related
    ENSCAFP00845008402.1, ENSCAFT00845010766.1
    Conserved Domains (4) summary
    cd01205
    Location:40 → 138
    EVH1_WASP-like; WASP family proteins EVH1 domain
    pfam00786
    Location:202 → 259
    PBD; P21-Rho-binding domain
    cd22074
    Location:402 → 428
    WH2_N-WASP_r1; first tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains
    cd22075
    Location:429 → 453
    WH2_hN-WASP_r2_like; second tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains

  2. XM_038686265.1 → XP_038542193.1  neural Wiskott-Aldrich syndrome protein isoform X2

    UniProtKB/TrEMBL
    A0A8C0YTV2
    Conserved Domains (4) summary
    cd01205
    Location:1 → 98
    EVH1_WASP-like; WASP family proteins EVH1 domain
    pfam00786
    Location:162 → 219
    PBD; P21-Rho-binding domain
    cd22074
    Location:362 → 388
    WH2_N-WASP_r1; first tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains
    cd22075
    Location:389 → 413
    WH2_hN-WASP_r2_like; second tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains

  3. XM_038686266.1 → XP_038542194.1  neural Wiskott-Aldrich syndrome protein isoform X2

    UniProtKB/TrEMBL
    A0A8C0YTV2
    Conserved Domains (4) summary
    cd01205
    Location:1 → 98
    EVH1_WASP-like; WASP family proteins EVH1 domain
    pfam00786
    Location:162 → 219
    PBD; P21-Rho-binding domain
    cd22074
    Location:362 → 388
    WH2_N-WASP_r1; first tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains
    cd22075
    Location:389 → 413
    WH2_hN-WASP_r2_like; second tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049274.1 Alternate UMICH_Zoey_3.1

    Range
    11795524..11868439
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038494345.1 → XP_038350273.1  neural Wiskott-Aldrich syndrome protein isoform X1

    Conserved Domains (4) summary
    cd01205
    Location:40 → 138
    EVH1_WASP-like; WASP family proteins EVH1 domain
    pfam00786
    Location:202 → 259
    PBD; P21-Rho-binding domain
    cd22074
    Location:402 → 428
    WH2_N-WASP_r1; first tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains
    cd22075
    Location:429 → 453
    WH2_hN-WASP_r2_like; second tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains

  2. XM_038494346.1 → XP_038350274.1  neural Wiskott-Aldrich syndrome protein isoform X2

    Conserved Domains (4) summary
    cd01205
    Location:1 → 98
    EVH1_WASP-like; WASP family proteins EVH1 domain
    pfam00786
    Location:162 → 219
    PBD; P21-Rho-binding domain
    cd22074
    Location:362 → 388
    WH2_N-WASP_r1; first tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains
    cd22075
    Location:389 → 413
    WH2_hN-WASP_r2_like; second tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains

  3. XM_038494347.1 → XP_038350275.1  neural Wiskott-Aldrich syndrome protein isoform X2

    Conserved Domains (4) summary
    cd01205
    Location:1 → 98
    EVH1_WASP-like; WASP family proteins EVH1 domain
    pfam00786
    Location:162 → 219
    PBD; P21-Rho-binding domain
    cd22074
    Location:362 → 388
    WH2_N-WASP_r1; first tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains
    cd22075
    Location:389 → 413
    WH2_hN-WASP_r2_like; second tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049755.1 Alternate UNSW_CanFamBas_1.0

    Range
    11533495..11606377
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038620573.1 → XP_038476501.1  neural Wiskott-Aldrich syndrome protein isoform X1

    Conserved Domains (4) summary
    cd01205
    Location:40 → 138
    EVH1_WASP-like; WASP family proteins EVH1 domain
    pfam00786
    Location:202 → 259
    PBD; P21-Rho-binding domain
    cd22074
    Location:402 → 428
    WH2_N-WASP_r1; first tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains
    cd22075
    Location:429 → 453
    WH2_hN-WASP_r2_like; second tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains

  2. XM_038620574.1 → XP_038476502.1  neural Wiskott-Aldrich syndrome protein isoform X2

    Conserved Domains (4) summary
    cd01205
    Location:1 → 98
    EVH1_WASP-like; WASP family proteins EVH1 domain
    pfam00786
    Location:162 → 219
    PBD; P21-Rho-binding domain
    cd22074
    Location:362 → 388
    WH2_N-WASP_r1; first tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains
    cd22075
    Location:389 → 413
    WH2_hN-WASP_r2_like; second tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains

  3. XM_038620575.1 → XP_038476503.1  neural Wiskott-Aldrich syndrome protein isoform X2

    Conserved Domains (4) summary
    cd01205
    Location:1 → 98
    EVH1_WASP-like; WASP family proteins EVH1 domain
    pfam00786
    Location:162 → 219
    PBD; P21-Rho-binding domain
    cd22074
    Location:362 → 388
    WH2_N-WASP_r1; first tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains
    cd22075
    Location:389 → 413
    WH2_hN-WASP_r2_like; second tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049235.1 Alternate UU_Cfam_GSD_1.0

    Range
    11774079..11846981
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038556644.1 → XP_038412572.1  neural Wiskott-Aldrich syndrome protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0M4U7, A0A8C0R5D1, A0A8C0YTV2, A0A8I3MR53
    Conserved Domains (4) summary
    cd01205
    Location:40 → 138
    EVH1_WASP-like; WASP family proteins EVH1 domain
    pfam00786
    Location:202 → 259
    PBD; P21-Rho-binding domain
    cd22074
    Location:402 → 428
    WH2_N-WASP_r1; first tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains
    cd22075
    Location:429 → 453
    WH2_hN-WASP_r2_like; second tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains

  2. XM_038556646.1 → XP_038412574.1  neural Wiskott-Aldrich syndrome protein isoform X2

    UniProtKB/TrEMBL
    A0A8C0YTV2
    Conserved Domains (4) summary
    cd01205
    Location:1 → 98
    EVH1_WASP-like; WASP family proteins EVH1 domain
    pfam00786
    Location:162 → 219
    PBD; P21-Rho-binding domain
    cd22074
    Location:362 → 388
    WH2_N-WASP_r1; first tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains
    cd22075
    Location:389 → 413
    WH2_hN-WASP_r2_like; second tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains

  3. XM_038556647.1 → XP_038412575.1  neural Wiskott-Aldrich syndrome protein isoform X2

    UniProtKB/TrEMBL
    A0A8C0YTV2
    Conserved Domains (4) summary
    cd01205
    Location:1 → 98
    EVH1_WASP-like; WASP family proteins EVH1 domain
    pfam00786
    Location:162 → 219
    PBD; P21-Rho-binding domain
    cd22074
    Location:362 → 388
    WH2_N-WASP_r1; first tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains
    cd22075
    Location:389 → 413
    WH2_hN-WASP_r2_like; second tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006596.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    11512373..11585271
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_532445.7 → XP_532445.3  neural Wiskott-Aldrich syndrome protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0M4U7, A0A8C0R5D1, A0A8C0YTV2, A0A8I3MR53
    Conserved Domains (4) summary
    cd01205
    Location:40 → 138
    EVH1_WASP-like; WASP family proteins EVH1 domain
    pfam00786
    Location:202 → 259
    PBD; P21-Rho-binding domain
    cd22074
    Location:402 → 428
    WH2_N-WASP_r1; first tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains
    cd22075
    Location:429 → 453
    WH2_hN-WASP_r2_like; second tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains

  2. XM_038436434.1 → XP_038292362.1  neural Wiskott-Aldrich syndrome protein isoform X2

    UniProtKB/TrEMBL
    A0A8C0YTV2
    Conserved Domains (4) summary
    cd01205
    Location:1 → 98
    EVH1_WASP-like; WASP family proteins EVH1 domain
    pfam00786
    Location:162 → 219
    PBD; P21-Rho-binding domain
    cd22074
    Location:362 → 388
    WH2_N-WASP_r1; first tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains
    cd22075
    Location:389 → 413
    WH2_hN-WASP_r2_like; second tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains

  3. XM_038436445.1 → XP_038292373.1  neural Wiskott-Aldrich syndrome protein isoform X2

    UniProtKB/TrEMBL
    A0A8C0YTV2
    Conserved Domains (4) summary
    cd01205
    Location:1 → 98
    EVH1_WASP-like; WASP family proteins EVH1 domain
    pfam00786
    Location:162 → 219
    PBD; P21-Rho-binding domain
    cd22074
    Location:362 → 388
    WH2_N-WASP_r1; first tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains
    cd22075
    Location:389 → 413
    WH2_hN-WASP_r2_like; second tandem Wiskott Aldrich syndrome homology region 2 (WH2 motif) repeat found in human Neural Wiskott-Aldrich syndrome protein (N-WASP) and related domains
Nucleotide Protein
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