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UBR5 ubiquitin protein ligase E3 component n-recognin 5 [ Canis lupus familiaris (dog) ]

Gene ID: 475055, updated on 5-Mar-2024

Summary

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Official Symbol
UBR5provided by VGNC
Official Full Name
ubiquitin protein ligase E3 component n-recognin 5provided by VGNC
Primary source
VGNC:VGNC:48092
See related
Ensembl:ENSCAFG00845007659
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
EDD1
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 13
Exon count:
59
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 13 NC_051817.1 (4047718..4183993, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 13 NC_006595.4 (3889598..4025534, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 13 NC_049234.1 (4020631..4156590, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 13 NC_049273.1 (3890615..4026582, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 13 NC_049754.1 (4003424..4139385, complement)

Chromosome 13 - NC_051817.1Genomic Context describing neighboring genes Neighboring gene neurocalcin delta Neighboring gene ubiquitin-conjugating enzyme E2 N-like Neighboring gene uncharacterized LOC102156908 Neighboring gene ribonucleotide reductase regulatory TP53 inducible subunit M2B Neighboring gene RNA-binding protein EWS-like Neighboring gene 60S ribosomal protein L29-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein polyubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of double-strand break repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase UBR5
Names
E3 ubiquitin protein ligase, HECT domain containing, 1
XP_005627895.1
XP_013974028.1
XP_013974029.1
XP_013974030.1
XP_022282306.1
XP_038348902.1
XP_038348903.1
XP_038348904.1
XP_038348905.1
XP_038348906.1
XP_038348907.1
XP_038411164.1
XP_038411165.1
XP_038411166.1
XP_038411167.1
XP_038411168.1
XP_038411169.1
XP_038475061.1
XP_038475062.1
XP_038475063.1
XP_038475064.1
XP_038475065.1
XP_038475066.1
XP_038540678.1
XP_038540679.1
XP_038540680.1
XP_038540681.1
XP_038540682.1
XP_038540683.1
XP_532290.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051817.1 Reference ROS_Cfam_1.0

    Range
    4047718..4183993 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038684754.1 → XP_038540682.1  E3 ubiquitin-protein ligase UBR5 isoform X5

    UniProtKB/TrEMBL
    A0A8C0JN17, A0A8C0QBA5
    Conserved Domains (4) summary
    smart00396
    Location:1171 → 1238
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2383 → 2446
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2494 → 2789
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  2. XM_038684753.1 → XP_038540681.1  E3 ubiquitin-protein ligase UBR5 isoform X4

    UniProtKB/TrEMBL
    A0A8C0JN17, A0A8C0QBA5
    Conserved Domains (4) summary
    smart00396
    Location:1171 → 1238
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2385 → 2448
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2496 → 2791
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  3. XM_038684751.1 → XP_038540679.1  E3 ubiquitin-protein ligase UBR5 isoform X2

    UniProtKB/TrEMBL
    A0A8C0JMU8, A0A8C0P2B1
    Conserved Domains (4) summary
    smart00396
    Location:1176 → 1243
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2390 → 2453
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2501 → 2796
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  4. XM_038684755.1 → XP_038540683.1  E3 ubiquitin-protein ligase UBR5 isoform X6

    UniProtKB/TrEMBL
    A0A8C0P2B1
    Conserved Domains (4) summary
    smart00396
    Location:1160 → 1227
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2374 → 2437
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2485 → 2780
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  5. XM_038684752.1 → XP_038540680.1  E3 ubiquitin-protein ligase UBR5 isoform X3

    UniProtKB/TrEMBL
    A0A8C0P2B1, A0A8C0QBC1, A0A8I3RVJ8
    Related
    ENSCAFP00845010556.1, ENSCAFT00845013594.1
    Conserved Domains (4) summary
    smart00396
    Location:1177 → 1244
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2389 → 2452
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2500 → 2795
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  6. XM_038684750.1 → XP_038540678.1  E3 ubiquitin-protein ligase UBR5 isoform X1

    UniProtKB/TrEMBL
    A0A8C0P2B1
    Conserved Domains (4) summary
    smart00396
    Location:1177 → 1244
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2391 → 2454
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2502 → 2797
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049273.1 Alternate UMICH_Zoey_3.1

    Range
    3890615..4026582 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038492978.1 → XP_038348906.1  E3 ubiquitin-protein ligase UBR5 isoform X5

    Conserved Domains (4) summary
    smart00396
    Location:1171 → 1238
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2383 → 2446
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2494 → 2789
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  2. XM_038492977.1 → XP_038348905.1  E3 ubiquitin-protein ligase UBR5 isoform X4

    Conserved Domains (4) summary
    smart00396
    Location:1171 → 1238
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2385 → 2448
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2496 → 2791
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  3. XM_038492975.1 → XP_038348903.1  E3 ubiquitin-protein ligase UBR5 isoform X2

    Conserved Domains (4) summary
    smart00396
    Location:1176 → 1243
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2390 → 2453
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2501 → 2796
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  4. XM_038492979.1 → XP_038348907.1  E3 ubiquitin-protein ligase UBR5 isoform X6

    Conserved Domains (4) summary
    smart00396
    Location:1160 → 1227
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2374 → 2437
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2485 → 2780
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  5. XM_038492976.1 → XP_038348904.1  E3 ubiquitin-protein ligase UBR5 isoform X3

    Conserved Domains (4) summary
    smart00396
    Location:1177 → 1244
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2389 → 2452
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2500 → 2795
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  6. XM_038492974.1 → XP_038348902.1  E3 ubiquitin-protein ligase UBR5 isoform X1

    Conserved Domains (4) summary
    smart00396
    Location:1177 → 1244
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2391 → 2454
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2502 → 2797
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049754.1 Alternate UNSW_CanFamBas_1.0

    Range
    4003424..4139385 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038619137.1 → XP_038475065.1  E3 ubiquitin-protein ligase UBR5 isoform X5

    Conserved Domains (4) summary
    smart00396
    Location:1171 → 1238
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2383 → 2446
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2494 → 2789
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  2. XM_038619136.1 → XP_038475064.1  E3 ubiquitin-protein ligase UBR5 isoform X4

    Conserved Domains (4) summary
    smart00396
    Location:1171 → 1238
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2385 → 2448
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2496 → 2791
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  3. XM_038619134.1 → XP_038475062.1  E3 ubiquitin-protein ligase UBR5 isoform X2

    Conserved Domains (4) summary
    smart00396
    Location:1176 → 1243
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2390 → 2453
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2501 → 2796
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  4. XM_038619138.1 → XP_038475066.1  E3 ubiquitin-protein ligase UBR5 isoform X6

    Conserved Domains (4) summary
    smart00396
    Location:1160 → 1227
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2374 → 2437
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2485 → 2780
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  5. XM_038619135.1 → XP_038475063.1  E3 ubiquitin-protein ligase UBR5 isoform X3

    Conserved Domains (4) summary
    smart00396
    Location:1177 → 1244
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2389 → 2452
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2500 → 2795
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  6. XM_038619133.1 → XP_038475061.1  E3 ubiquitin-protein ligase UBR5 isoform X1

    Conserved Domains (4) summary
    smart00396
    Location:1177 → 1244
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2391 → 2454
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2502 → 2797
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049234.1 Alternate UU_Cfam_GSD_1.0

    Range
    4020631..4156590 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038555240.1 → XP_038411168.1  E3 ubiquitin-protein ligase UBR5 isoform X5

    UniProtKB/TrEMBL
    A0A8C0JN17, A0A8C0QBA5
    Conserved Domains (4) summary
    smart00396
    Location:1171 → 1238
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2383 → 2446
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2494 → 2789
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  2. XM_038555239.1 → XP_038411167.1  E3 ubiquitin-protein ligase UBR5 isoform X4

    UniProtKB/TrEMBL
    A0A8C0JN17, A0A8C0QBA5
    Conserved Domains (4) summary
    smart00396
    Location:1171 → 1238
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2385 → 2448
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2496 → 2791
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  3. XM_038555237.1 → XP_038411165.1  E3 ubiquitin-protein ligase UBR5 isoform X2

    UniProtKB/TrEMBL
    A0A8C0JMU8, A0A8C0P2B1
    Conserved Domains (4) summary
    smart00396
    Location:1176 → 1243
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2390 → 2453
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2501 → 2796
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  4. XM_038555241.1 → XP_038411169.1  E3 ubiquitin-protein ligase UBR5 isoform X6

    UniProtKB/TrEMBL
    A0A8C0P2B1
    Conserved Domains (4) summary
    smart00396
    Location:1160 → 1227
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2374 → 2437
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2485 → 2780
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  5. XM_038555238.1 → XP_038411166.1  E3 ubiquitin-protein ligase UBR5 isoform X3

    UniProtKB/TrEMBL
    A0A8C0P2B1, A0A8C0QBC1, A0A8I3RVJ8
    Conserved Domains (4) summary
    smart00396
    Location:1177 → 1244
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2389 → 2452
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2500 → 2795
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  6. XM_038555236.1 → XP_038411164.1  E3 ubiquitin-protein ligase UBR5 isoform X1

    UniProtKB/TrEMBL
    A0A8C0P2B1
    Conserved Domains (4) summary
    smart00396
    Location:1177 → 1244
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2391 → 2454
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2502 → 2797
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006595.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    3889598..4025534 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005627838.4 → XP_005627895.1  E3 ubiquitin-protein ligase UBR5 isoform X5

    UniProtKB/TrEMBL
    A0A8C0JN17, A0A8C0QBA5
    Conserved Domains (4) summary
    smart00396
    Location:1171 → 1238
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2383 → 2446
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2494 → 2789
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  2. XM_014118554.3 → XP_013974029.1  E3 ubiquitin-protein ligase UBR5 isoform X4

    UniProtKB/TrEMBL
    A0A8C0JN17, A0A8C0QBA5
    Conserved Domains (4) summary
    smart00396
    Location:1171 → 1238
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2385 → 2448
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2496 → 2791
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  3. XM_022426598.2 → XP_022282306.1  E3 ubiquitin-protein ligase UBR5 isoform X2

    UniProtKB/TrEMBL
    A0A8C0JMU8, A0A8C0P2B1
    Conserved Domains (4) summary
    smart00396
    Location:1176 → 1243
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2390 → 2453
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2501 → 2796
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  4. XM_014118555.3 → XP_013974030.1  E3 ubiquitin-protein ligase UBR5 isoform X6

    UniProtKB/TrEMBL
    A0A8C0P2B1
    Conserved Domains (4) summary
    smart00396
    Location:1160 → 1227
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2374 → 2437
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2485 → 2780
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  5. XM_532290.7 → XP_532290.2  E3 ubiquitin-protein ligase UBR5 isoform X3

    UniProtKB/TrEMBL
    A0A8C0P2B1, A0A8C0QBC1, A0A8I3RVJ8
    Conserved Domains (4) summary
    smart00396
    Location:1177 → 1244
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2389 → 2452
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2500 → 2795
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins

  6. XM_014118553.3 → XP_013974028.1  E3 ubiquitin-protein ligase UBR5 isoform X1

    UniProtKB/TrEMBL
    A0A8C0P2B1
    Conserved Domains (4) summary
    smart00396
    Location:1177 → 1244
    ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
    smart00517
    Location:2391 → 2454
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    smart00119
    Location:2502 → 2797
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd14423
    Location:184 → 230
    CUE_UBR5; CUE domain found in E3 ubiquitin-protein ligase UBR5 and similar proteins
Nucleotide Protein
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