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ORC3 origin recognition complex subunit 3 [ Canis lupus familiaris (dog) ]

Gene ID: 474991, updated on 5-Mar-2024

Summary

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Official Symbol
ORC3provided by VGNC
Official Full Name
origin recognition complex subunit 3provided by VGNC
Primary source
VGNC:VGNC:44142
See related
Ensembl:ENSCAFG00845005944
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
ORC3L
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
20
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (47853551..47913880)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (46855302..46915592)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (47261944..47323195)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (47145146..47206401)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (47072621..47133465)

Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 35 member A1 Neighboring gene arginyl-tRNA synthetase 2, mitochondrial Neighboring gene high mobility group protein B1-like Neighboring gene akirin 2 Neighboring gene uncharacterized LOC111098350

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA replication origin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA replication initiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of DNA replication preinitiation complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of nuclear origin of replication recognition complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of nuclear pre-replicative complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
origin recognition complex subunit 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051816.1 Reference ROS_Cfam_1.0

    Range
    47853551..47913880
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038684117.1 → XP_038540045.1  origin recognition complex subunit 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0S4W9
    Conserved Domains (2) summary
    pfam07034
    Location:18 → 344
    ORC3_N; Origin recognition complex (ORC) subunit 3 N-terminus
    pfam18137
    Location:597 → 672
    ORC_WH_C; Origin recognition complex winged helix C-terminal

  2. XM_038684115.1 → XP_038540043.1  origin recognition complex subunit 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0S4W9
    Conserved Domains (2) summary
    pfam07034
    Location:18 → 344
    ORC3_N; Origin recognition complex (ORC) subunit 3 N-terminus
    pfam18137
    Location:597 → 709
    ORC_WH_C; Origin recognition complex winged helix C-terminal

  3. XM_038684116.1 → XP_038540044.1  origin recognition complex subunit 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0S4W9
    Conserved Domains (2) summary
    pfam07034
    Location:18 → 343
    ORC3_N; Origin recognition complex (ORC) subunit 3 N-terminus
    pfam18137
    Location:596 → 708
    ORC_WH_C; Origin recognition complex winged helix C-terminal

  4. XM_038684118.1 → XP_038540046.1  origin recognition complex subunit 3 isoform X4

    UniProtKB/TrEMBL
    A0A8C0S4W9
    Conserved Domains (2) summary
    pfam07034
    Location:18 → 309
    ORC3_N; Origin recognition complex (ORC) subunit 3 N-terminus
    pfam18137
    Location:562 → 674
    ORC_WH_C; Origin recognition complex winged helix C-terminal

  5. XM_038684120.1 → XP_038540048.1  origin recognition complex subunit 3 isoform X6

    UniProtKB/TrEMBL
    A0A8C0S518
    Conserved Domains (2) summary
    pfam07034
    Location:1 → 201
    ORC3_N; Origin recognition complex (ORC) subunit 3 N-terminus
    cd20704
    Location:432 → 566
    Orc3; Origin recognition complex subunit 3

  6. XM_038684119.1 → XP_038540047.1  origin recognition complex subunit 3 isoform X5

    UniProtKB/TrEMBL
    A0A8C0S518
    Related
    ENSCAFP00845008183.1, ENSCAFT00845010520.1
    Conserved Domains (2) summary
    pfam07034
    Location:1 → 291
    ORC3_N; Origin recognition complex (ORC) subunit 3 N-terminus
    pfam18137
    Location:544 → 656
    ORC_WH_C; Origin recognition complex winged helix C-terminal

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049272.1 Alternate UMICH_Zoey_3.1

    Range
    47145146..47206401
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038492395.1 → XP_038348323.1  origin recognition complex subunit 3 isoform X3

  2. XM_038492393.1 → XP_038348321.1  origin recognition complex subunit 3 isoform X1

  3. XM_038492394.1 → XP_038348322.1  origin recognition complex subunit 3 isoform X2

  4. XM_038492396.1 → XP_038348324.1  origin recognition complex subunit 3 isoform X4

  5. XM_038492398.1 → XP_038348326.1  origin recognition complex subunit 3 isoform X6

  6. XM_038492397.1 → XP_038348325.1  origin recognition complex subunit 3 isoform X5

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

    Range
    47072621..47133465
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038618558.1 → XP_038474486.1  origin recognition complex subunit 3 isoform X3

  2. XM_038618556.1 → XP_038474484.1  origin recognition complex subunit 3 isoform X1

  3. XM_038618557.1 → XP_038474485.1  origin recognition complex subunit 3 isoform X2

  4. XM_038618559.1 → XP_038474487.1  origin recognition complex subunit 3 isoform X4

  5. XM_038618562.1 → XP_038474490.1  origin recognition complex subunit 3 isoform X6

  6. XM_038618561.1 → XP_038474489.1  origin recognition complex subunit 3 isoform X5

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

    Range
    47261944..47323195
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038554687.1 → XP_038410615.1  origin recognition complex subunit 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0S4W9

  2. XM_038554685.1 → XP_038410613.1  origin recognition complex subunit 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KSV7, A0A8C0S4W9

  3. XM_038554686.1 → XP_038410614.1  origin recognition complex subunit 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0S4W9

  4. XM_038554688.1 → XP_038410616.1  origin recognition complex subunit 3 isoform X4

    UniProtKB/TrEMBL
    A0A8C0S4H7, A0A8C0S4W9

  5. XM_038554691.1 → XP_038410619.1  origin recognition complex subunit 3 isoform X6

    UniProtKB/TrEMBL
    A0A8C0S518

  6. XM_038554689.1 → XP_038410617.1  origin recognition complex subunit 3 isoform X5

    UniProtKB/TrEMBL
    A0A8C0S518

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    46855302..46915592
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005627615.4 → XP_005627672.1  origin recognition complex subunit 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0S4W9
    Conserved Domains (2) summary
    pfam07034
    Location:41 → 344
    ORC3_N; Origin recognition complex (ORC) subunit 3 N-terminus
    cl28312
    Location:457 → 624
    UvrD; Superfamily I DNA or RNA helicase [Replication, recombination and repair]

  2. XM_532228.7 → XP_532228.2  origin recognition complex subunit 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KSV7, A0A8C0S4W9
    Conserved Domains (2) summary
    pfam07034
    Location:41 → 344
    ORC3_N; Origin recognition complex (ORC) subunit 3 N-terminus
    cl28312
    Location:457 → 704
    UvrD; Superfamily I DNA or RNA helicase [Replication, recombination and repair]

  3. XM_022426335.2 → XP_022282043.1  origin recognition complex subunit 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0S4W9
    Conserved Domains (2) summary
    pfam07034
    Location:41 → 343
    ORC3_N; Origin recognition complex (ORC) subunit 3 N-terminus
    cl28312
    Location:456 → 703
    UvrD; Superfamily I DNA or RNA helicase [Replication, recombination and repair]

  4. XM_022426336.2 → XP_022282044.1  origin recognition complex subunit 3 isoform X4

    UniProtKB/TrEMBL
    A0A8C0S4H7, A0A8C0S4W9
    Conserved Domains (2) summary
    pfam07034
    Location:41 → 309
    ORC3_N; Origin recognition complex (ORC) subunit 3 N-terminus
    cl28312
    Location:422 → 669
    UvrD; Superfamily I DNA or RNA helicase [Replication, recombination and repair]

  5. XM_022426337.2 → XP_022282045.1  origin recognition complex subunit 3 isoform X6

    UniProtKB/TrEMBL
    A0A8C0S518
    Conserved Domains (2) summary
    pfam07034
    Location:1 → 201
    ORC3_N; Origin recognition complex (ORC) subunit 3 N-terminus
    cl28312
    Location:314 → 561
    UvrD; Superfamily I DNA or RNA helicase [Replication, recombination and repair]

  6. XM_014118137.3 → XP_013973612.1  origin recognition complex subunit 3 isoform X5

    UniProtKB/TrEMBL
    A0A8C0S518
    Conserved Domains (2) summary
    pfam07034
    Location:1 → 291
    ORC3_N; Origin recognition complex (ORC) subunit 3 N-terminus
    cl28312
    Location:404 → 651
    UvrD; Superfamily I DNA or RNA helicase [Replication, recombination and repair]
Nucleotide Protein
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