ALAD aminolevulinate dehydratase [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: ALADprovided by VGNC
Official Full Name: aminolevulinate dehydrataseprovided by VGNC
Primary source: VGNC:VGNC:37775
See related: Ensembl:ENSCAFG00845007987
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	11	NC_051815.1 (68860894..68876553, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	11	NC_006593.4 (66141416..66157086, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	11	NC_049232.1 (68146847..68162517, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	11	NC_049271.1 (67378968..67394637, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	11	NC_049752.1 (67409910..67425556, complement)

Chromosome 11 - NC_051815.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables porphobilinogen synthase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in heme biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: delta-aminolevulinic acid dehydratase

Names: aminolevulinate, delta-, dehydratase

XP_038346958.1

EC 4.2.1.24

XP_038409098.1

EC 4.2.1.24

XP_038472977.1

EC 4.2.1.24

XP_038538427.1

EC 4.2.1.24

XP_855370.1

EC 4.2.1.24

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051815.1 Reference ROS_Cfam_1.0

Range

68860894..68876553 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038682499.1 → XP_038538427.1 delta-aminolevulinic acid dehydratase

UniProtKB/TrEMBL

A0A8C0LEV1, A0A8C0Q968, A0A8I3N580

Related

ENSCAFP00845010889.1, ENSCAFT00845014050.1

Conserved Domains (1) summary

cd04824
Location:8 → 327

eu_ALAD_PBGS_cysteine_rich; Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049271.1 Alternate UMICH_Zoey_3.1

Range

67378968..67394637 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038491030.1 → XP_038346958.1 delta-aminolevulinic acid dehydratase

Conserved Domains (1) summary

cd04824
Location:8 → 327

eu_ALAD_PBGS_cysteine_rich; Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the ...

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049752.1 Alternate UNSW_CanFamBas_1.0

Range

67409910..67425556 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038617049.1 → XP_038472977.1 delta-aminolevulinic acid dehydratase

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049232.1 Alternate UU_Cfam_GSD_1.0

Range

68146847..68162517 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038553170.1 → XP_038409098.1 delta-aminolevulinic acid dehydratase

UniProtKB/TrEMBL

A0A8C0LEV1, A0A8C0Q968, A0A8I3N580

Conserved Domains (1) summary

cd04824
Location:8 → 327

eu_ALAD_PBGS_cysteine_rich; Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006593.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

66141416..66157086 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_850277.6 → XP_855370.1 delta-aminolevulinic acid dehydratase

UniProtKB/TrEMBL

A0A8C0LEV1, A0A8C0Q968, A0A8I3N580

Conserved Domains (1) summary

cd04824
Location:8 → 327

eu_ALAD_PBGS_cysteine_rich; Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the ...