U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SOCS5 suppressor of cytokine signaling 5 [ Canis lupus familiaris (dog) ]

Gene ID: 474581, updated on 11-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
SOCS5provided by VGNC
Official Full Name
suppressor of cytokine signaling 5provided by VGNC
Primary source
VGNC:VGNC:46652
See related
Ensembl:ENSCAFG00845028095
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 10
Exon count:
4
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (49786401..49847931)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (48769314..48830770)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (49967638..50029159)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (49494260..49555954)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (49784343..49845789)

Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106559415 Neighboring gene CXXC repeat containing interactor of PDZ3 domain Neighboring gene uncharacterized LOC111097738 Neighboring gene uncharacterized LOC111097739 Neighboring gene guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10-like Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in epidermal growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
suppressor of cytokine signaling 5

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051814.1 Reference ROS_Cfam_1.0

    Range
    49786401..49847931
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038680498.1 → XP_038536426.1  suppressor of cytokine signaling 5

    UniProtKB/TrEMBL
    A0A8C0LRK7, A0A8C0MZX4, A0A8I3PW31, A0A8I3SBB2, A0A8P0S8E8
    Related
    ENSCAFP00845038889.1, ENSCAFT00845049576.1
    Conserved Domains (3) summary
    cd03739
    Location:479 → 534
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 195
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain

  2. XM_038680496.1 → XP_038536424.1  suppressor of cytokine signaling 5

    UniProtKB/TrEMBL
    A0A8C0LRK7, A0A8C0MZX4, A0A8I3PW31, A0A8I3SBB2, A0A8P0S8E8
    Related
    ENSCAFP00845038904.1, ENSCAFT00845049597.1
    Conserved Domains (3) summary
    cd03739
    Location:479 → 534
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 195
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain

  3. XM_038680497.1 → XP_038536425.1  suppressor of cytokine signaling 5

    UniProtKB/TrEMBL
    A0A8C0LRK7, A0A8C0MZX4, A0A8I3PW31, A0A8I3SBB2, A0A8P0S8E8
    Conserved Domains (3) summary
    cd03739
    Location:479 → 534
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 195
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049270.1 Alternate UMICH_Zoey_3.1

    Range
    49494260..49555954
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038489214.1 → XP_038345142.1  suppressor of cytokine signaling 5

    Conserved Domains (3) summary
    cd03739
    Location:479 → 534
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 195
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain

  2. XM_038489212.1 → XP_038345140.1  suppressor of cytokine signaling 5

    Conserved Domains (3) summary
    cd03739
    Location:479 → 534
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 195
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain

  3. XM_038489213.1 → XP_038345141.1  suppressor of cytokine signaling 5

    Conserved Domains (3) summary
    cd03739
    Location:479 → 534
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 195
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

    Range
    49784343..49845789
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038615114.1 → XP_038471042.1  suppressor of cytokine signaling 5

    Conserved Domains (3) summary
    cd03739
    Location:479 → 534
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 195
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain

  2. XM_038615112.1 → XP_038471040.1  suppressor of cytokine signaling 5

    Conserved Domains (3) summary
    cd03739
    Location:479 → 534
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 195
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain

  3. XM_038615113.1 → XP_038471041.1  suppressor of cytokine signaling 5

    Conserved Domains (3) summary
    cd03739
    Location:479 → 534
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 195
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

    Range
    49967638..50029159
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038551216.1 → XP_038407144.1  suppressor of cytokine signaling 5

    UniProtKB/TrEMBL
    A0A8C0LRK7, A0A8C0MZX4, A0A8I3PW31, A0A8I3SBB2, A0A8P0S8E8
    Conserved Domains (3) summary
    cd03739
    Location:479 → 534
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 195
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain

  2. XM_038551214.1 → XP_038407142.1  suppressor of cytokine signaling 5

    UniProtKB/TrEMBL
    A0A8C0LRK7, A0A8C0MZX4, A0A8I3PW31, A0A8I3SBB2, A0A8P0S8E8
    Conserved Domains (3) summary
    cd03739
    Location:479 → 534
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 195
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain

  3. XM_038551215.1 → XP_038407143.1  suppressor of cytokine signaling 5

    UniProtKB/TrEMBL
    A0A8C0LRK7, A0A8C0MZX4, A0A8I3PW31, A0A8I3SBB2, A0A8P0S8E8
    Conserved Domains (3) summary
    cd03739
    Location:479 → 534
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 195
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    48769314..48830770
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038646774.1 → XP_038502702.1  suppressor of cytokine signaling 5

    UniProtKB/TrEMBL
    A0A8C0LRK7, A0A8C0MZX4, A0A8I3PW31, A0A8I3SBB2, A0A8P0S8E8
    Conserved Domains (3) summary
    cd03739
    Location:479 → 534
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 195
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain

  2. XM_038646754.1 → XP_038502682.1  suppressor of cytokine signaling 5

    UniProtKB/TrEMBL
    A0A8C0LRK7, A0A8C0MZX4, A0A8I3PW31, A0A8I3SBB2, A0A8P0S8E8
    Conserved Domains (3) summary
    cd03739
    Location:479 → 534
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 195
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain

  3. XM_005626083.4 → XP_005626140.1  suppressor of cytokine signaling 5

    UniProtKB/TrEMBL
    A0A8C0LRK7, A0A8C0MZX4, A0A8I3PW31, A0A8I3SBB2, A0A8P0S8E8
    Conserved Domains (3) summary
    cd03739
    Location:479 → 534
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 195
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.