TBC1D8 TBC1 domain family member 8 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: TBC1D8provided by VGNC
Official Full Name: TBC1 domain family member 8provided by VGNC
Primary source: VGNC:VGNC:47151
See related: Ensembl:ENSCAFG00845012925
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 20

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	10	NC_051814.1 (42587181..42700001)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	10	NC_006592.4 (41644404..41757232)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	10	NC_049231.1 (42773777..42886785)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	10	NC_049270.1 (42299601..42411825)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	10	NC_049751.1 (42582407..42695032)

Chromosome 10 - NC_051814.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

General protein information

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Preferred Names: TBC1 domain family member 8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051814.1 Reference ROS_Cfam_1.0

Range

42587181..42700001

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038680271.1 → XP_038536199.1 TBC1 domain family member 8 isoform X1

UniProtKB/TrEMBL

A0A8C0NJB6, A0A8I3NIQ0

Related

ENSCAFP00845018242.1, ENSCAFT00845023256.1

Conserved Domains (3) summary

smart00164
Location:520 → 724

TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

cd13349
Location:171 → 269

PH-GRAM1_TBC1D8; TBC1 domain family member 8 (TBC1D8; also called Vascular Rab-GAP/TBC-containing protein) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1

cd13353
Location:311 → 406

PH-GRAM2_TBC1D8; TBC1 domain family member 8 (TBC1D8; also called Vascular Rab-GAP/TBC-containing protein) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 2
XM_038680272.1 → XP_038536200.1 TBC1 domain family member 8 isoform X2

UniProtKB/TrEMBL

A0A8C0NJB6

Related

ENSCAFP00845018137.1, ENSCAFT00845023135.1

Conserved Domains (3) summary

smart00164
Location:505 → 709

TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

cd13349
Location:156 → 254

PH-GRAM1_TBC1D8; TBC1 domain family member 8 (TBC1D8; also called Vascular Rab-GAP/TBC-containing protein) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1

cd13353
Location:296 → 391

PH-GRAM2_TBC1D8; TBC1 domain family member 8 (TBC1D8; also called Vascular Rab-GAP/TBC-containing protein) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 2

Alternate UMICH_Zoey_3.1

Genomic

NC_049270.1 Alternate UMICH_Zoey_3.1

Range

42299601..42411825

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038489002.1 → XP_038344930.1 TBC1 domain family member 8 isoform X1

Conserved Domains (3) summary

smart00164
Location:520 → 724

TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

cd13349
Location:171 → 269

PH-GRAM1_TBC1D8; TBC1 domain family member 8 (TBC1D8; also called Vascular Rab-GAP/TBC-containing protein) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1

cd13353
Location:311 → 406

PH-GRAM2_TBC1D8; TBC1 domain family member 8 (TBC1D8; also called Vascular Rab-GAP/TBC-containing protein) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 2
XM_038489003.1 → XP_038344931.1 TBC1 domain family member 8 isoform X2

Conserved Domains (3) summary

smart00164
Location:505 → 709

TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

cd13349
Location:156 → 254

PH-GRAM1_TBC1D8; TBC1 domain family member 8 (TBC1D8; also called Vascular Rab-GAP/TBC-containing protein) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1

cd13353
Location:296 → 391

PH-GRAM2_TBC1D8; TBC1 domain family member 8 (TBC1D8; also called Vascular Rab-GAP/TBC-containing protein) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 2

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049751.1 Alternate UNSW_CanFamBas_1.0

Range

42582407..42695032

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038614894.1 → XP_038470822.1 TBC1 domain family member 8 isoform X1
XM_038614895.1 → XP_038470823.1 TBC1 domain family member 8 isoform X2

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049231.1 Alternate UU_Cfam_GSD_1.0

Range

42773777..42886785

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038550990.1 → XP_038406918.1 TBC1 domain family member 8 isoform X1

UniProtKB/TrEMBL

A0A8C0NJB6
XM_038550991.1 → XP_038406919.1 TBC1 domain family member 8 isoform X2

UniProtKB/TrEMBL

A0A8C0NJB6

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

41644404..41757232

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038644555.1 → XP_038500483.1 TBC1 domain family member 8 isoform X1

UniProtKB/TrEMBL

A0A8C0NJB6, A0A8C0SJV8, A0A8P0N5B5

Conserved Domains (3) summary

smart00164
Location:520 → 724

TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

cd13349
Location:171 → 269

PH-GRAM1_TBC1D8; TBC1 domain family member 8 (TBC1D8; also called Vascular Rab-GAP/TBC-containing protein) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1

cd13353
Location:311 → 406

PH-GRAM2_TBC1D8; TBC1 domain family member 8 (TBC1D8; also called Vascular Rab-GAP/TBC-containing protein) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 2
XM_038644562.1 → XP_038500490.1 TBC1 domain family member 8 isoform X2

UniProtKB/TrEMBL

A0A8C0NJB6

Conserved Domains (3) summary

smart00164
Location:505 → 709

TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

cd13349
Location:156 → 254

PH-GRAM1_TBC1D8; TBC1 domain family member 8 (TBC1D8; also called Vascular Rab-GAP/TBC-containing protein) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1

cd13353
Location:296 → 391

PH-GRAM2_TBC1D8; TBC1 domain family member 8 (TBC1D8; also called Vascular Rab-GAP/TBC-containing protein) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 2