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FHL2 four and a half LIM domains 2 [ Canis lupus familiaris (dog) ]

Gene ID: 474544, updated on 5-Mar-2024

Summary

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Official Symbol
FHL2provided by VGNC
Official Full Name
four and a half LIM domains 2provided by VGNC
Primary source
VGNC:VGNC:40872
See related
Ensembl:ENSCAFG00845009612
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
11
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (38854939..38922615)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (37924199..37991867)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (39050777..39118466)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (38579623..38647260)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (38859021..38926610)

Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119873770 Neighboring gene uncharacterized LOC102155326 Neighboring gene uncharacterized LOC111097692 Neighboring gene uncharacterized LOC111097691 Neighboring gene U6 spliceosomal RNA Neighboring gene chromosome 10 C2orf49 homolog Neighboring gene uncharacterized LOC106559387 Neighboring gene transforming growth factor beta receptor associated protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables transcription coregulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of calcineurin-NFAT signaling cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Z disc IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
four and a half LIM domains protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051814.1 Reference ROS_Cfam_1.0

    Range
    38854939..38922615
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038680169.1 → XP_038536097.1  four and a half LIM domains protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KBV8, A0A8C0PHY3, A0A8I3NCC4, A0A8I3NEJ6, A0A8P0S7Y2
    Related
    ENSCAFP00845013189.1, ENSCAFT00845016942.1
    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  2. XM_038680175.1 → XP_038536103.1  four and a half LIM domains protein 2 isoform X2

    Conserved Domains (2) summary
    cd09433
    Location:113 → 170
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:54 → 110
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  3. XM_038680172.1 → XP_038536100.1  four and a half LIM domains protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KBV8, A0A8C0PHY3, A0A8I3NCC4, A0A8I3NEJ6, A0A8P0S7Y2
    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  4. XM_038680173.1 → XP_038536101.1  four and a half LIM domains protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KBV8, A0A8C0PHY3, A0A8I3NCC4, A0A8I3NEJ6, A0A8P0S7Y2
    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  5. XM_038680171.1 → XP_038536099.1  four and a half LIM domains protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KBV8, A0A8C0PHY3, A0A8I3NCC4, A0A8I3NEJ6, A0A8P0S7Y2
    Related
    ENSCAFP00845013215.1, ENSCAFT00845016969.1
    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  6. XM_038680170.1 → XP_038536098.1  four and a half LIM domains protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KBV8, A0A8C0PHY3, A0A8I3NCC4, A0A8I3NEJ6, A0A8P0S7Y2
    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  7. XM_038680174.1 → XP_038536102.1  four and a half LIM domains protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KBV8, A0A8C0PHY3, A0A8I3NCC4, A0A8I3NEJ6, A0A8P0S7Y2
    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049270.1 Alternate UMICH_Zoey_3.1

    Range
    38579623..38647260
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038488917.1 → XP_038344845.1  four and a half LIM domains protein 2 isoform X1

    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  2. XM_038488924.1 → XP_038344852.1  four and a half LIM domains protein 2 isoform X2

    Conserved Domains (2) summary
    cd09433
    Location:113 → 170
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:54 → 110
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  3. XM_038488921.1 → XP_038344849.1  four and a half LIM domains protein 2 isoform X1

    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  4. XM_038488922.1 → XP_038344850.1  four and a half LIM domains protein 2 isoform X1

    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  5. XM_038488919.1 → XP_038344847.1  four and a half LIM domains protein 2 isoform X1

    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  6. XM_038488918.1 → XP_038344846.1  four and a half LIM domains protein 2 isoform X1

    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  7. XM_038488923.1 → XP_038344851.1  four and a half LIM domains protein 2 isoform X1

    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

    Range
    38859021..38926610
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038614797.1 → XP_038470725.1  four and a half LIM domains protein 2 isoform X1

    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  2. XM_038614803.1 → XP_038470731.1  four and a half LIM domains protein 2 isoform X2

    Conserved Domains (2) summary
    cd09433
    Location:113 → 170
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:54 → 110
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  3. XM_038614799.1 → XP_038470727.1  four and a half LIM domains protein 2 isoform X1

    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  4. XM_038614800.1 → XP_038470728.1  four and a half LIM domains protein 2 isoform X1

    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  5. XM_038614802.1 → XP_038470730.1  four and a half LIM domains protein 2 isoform X1

    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  6. XM_038614798.1 → XP_038470726.1  four and a half LIM domains protein 2 isoform X1

    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  7. XM_038614801.1 → XP_038470729.1  four and a half LIM domains protein 2 isoform X1

    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

    Range
    39050777..39118466
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038550886.1 → XP_038406814.1  four and a half LIM domains protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KBV8, A0A8C0PHY3, A0A8I3NCC4, A0A8I3NEJ6, A0A8P0S7Y2
    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  2. XM_038550892.1 → XP_038406820.1  four and a half LIM domains protein 2 isoform X2

    Conserved Domains (2) summary
    cd09433
    Location:113 → 170
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:54 → 110
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  3. XM_038550889.1 → XP_038406817.1  four and a half LIM domains protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KBV8, A0A8C0PHY3, A0A8I3NCC4, A0A8I3NEJ6, A0A8P0S7Y2
    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  4. XM_038550890.1 → XP_038406818.1  four and a half LIM domains protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KBV8, A0A8C0PHY3, A0A8I3NCC4, A0A8I3NEJ6, A0A8P0S7Y2
    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  5. XM_038550888.1 → XP_038406816.1  four and a half LIM domains protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KBV8, A0A8C0PHY3, A0A8I3NCC4, A0A8I3NEJ6, A0A8P0S7Y2
    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  6. XM_038550887.1 → XP_038406815.1  four and a half LIM domains protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KBV8, A0A8C0PHY3, A0A8I3NCC4, A0A8I3NEJ6, A0A8P0S7Y2
    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  7. XM_038550891.1 → XP_038406819.1  four and a half LIM domains protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KBV8, A0A8C0PHY3, A0A8I3NCC4, A0A8I3NEJ6, A0A8P0S7Y2
    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    37924199..37991867
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_531773.7 → XP_531773.3  four and a half LIM domains protein 2 isoform X1

    See identical proteins and their annotated locations for XP_531773.3

    UniProtKB/TrEMBL
    A0A8C0KBV8, A0A8C0PHY3, A0A8I3NCC4, A0A8I3NEJ6, A0A8P0S7Y2
    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  2. XM_038643656.1 → XP_038499584.1  four and a half LIM domains protein 2 isoform X2

    Conserved Domains (2) summary
    cd09433
    Location:113 → 170
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:54 → 110
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  3. XM_005625988.4 → XP_005626045.1  four and a half LIM domains protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005626045.1

    UniProtKB/TrEMBL
    A0A8C0KBV8, A0A8C0PHY3, A0A8I3NCC4, A0A8I3NEJ6, A0A8P0S7Y2
    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  4. XM_022424545.2 → XP_022280253.1  four and a half LIM domains protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KBV8, A0A8C0PHY3, A0A8I3NCC4, A0A8I3NEJ6, A0A8P0S7Y2
    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  5. XM_005625987.4 → XP_005626044.1  four and a half LIM domains protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005626044.1

    UniProtKB/TrEMBL
    A0A8C0KBV8, A0A8C0PHY3, A0A8I3NCC4, A0A8I3NEJ6, A0A8P0S7Y2
    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  6. XM_005625989.4 → XP_005626046.1  four and a half LIM domains protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005626046.1

    UniProtKB/TrEMBL
    A0A8C0KBV8, A0A8C0PHY3, A0A8I3NCC4, A0A8I3NEJ6, A0A8P0S7Y2
    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  7. XM_038643648.1 → XP_038499576.1  four and a half LIM domains protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KBV8, A0A8C0PHY3, A0A8I3NCC4, A0A8I3NEJ6, A0A8P0S7Y2
    Conserved Domains (2) summary
    cd09433
    Location:221 → 278
    LIM4_FHL2; The fourth LIM domain of Four and a half LIM domains protein 2 (FHL2)
    cl02475
    Location:101 → 157
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
Nucleotide Protein
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