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RBX1 ring-box 1 [ Canis lupus familiaris (dog) ]

Gene ID: 474494, updated on 5-Mar-2024

Summary

Official Symbol
RBX1provided by VGNC
Official Full Name
ring-box 1provided by VGNC
Primary source
VGNC:VGNC:108215
See related
Ensembl:ENSCAFG00845019033
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: 10
Exon count:
5
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (25014111..25028037, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (24200859..24214782, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (25224699..25238847, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (24729691..24743612, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (25050324..25064237, complement)

Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119873626 Neighboring gene uncharacterized LOC111097642 Neighboring gene uncharacterized LOC119873758 Neighboring gene U6 spliceosomal RNA Neighboring gene X-prolyl aminopeptidase 3 Neighboring gene uncharacterized LOC119873627

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cullin family protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of cullin-RING ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
E3 ubiquitin-protein ligase RBX1
XP_005625896.1
XP_038344447.1
XP_038344448.1
XP_038406377.1
XP_038406378.1
XP_038470342.1
XP_038470343.1
XP_038535683.1
XP_038535684.1
XP_531722.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051814.1 Reference ROS_Cfam_1.0

    Range
    25014111..25028037 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038679756.1XP_038535684.1  E3 ubiquitin-protein ligase RBX1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3PFV1, A0A8P0T5W7
    Related
    ENSCAFP00845026381.1, ENSCAFT00845033698.1
    Conserved Domains (1) summary
    cl17238
    Location:2076
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
  2. XM_038679755.1XP_038535683.1  E3 ubiquitin-protein ligase RBX1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0JMB1, A0A8C0T401, A0A8I3NXW3
    Related
    ENSCAFP00845026293.1, ENSCAFT00845033585.1
    Conserved Domains (1) summary
    cd16485
    Location:40101
    mRING-H2-C3H2C2D_RBX1; modified RING finger, H2 subclass (C3H2C2D-type), found in RING-box protein 1 (RBX1) and similar proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049270.1 Alternate UMICH_Zoey_3.1

    Range
    24729691..24743612 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038488520.1XP_038344448.1  E3 ubiquitin-protein ligase RBX1 isoform X2

    Conserved Domains (1) summary
    cl17238
    Location:2076
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
  2. XM_038488519.1XP_038344447.1  E3 ubiquitin-protein ligase RBX1 isoform X1

    Conserved Domains (1) summary
    cd16485
    Location:40101
    mRING-H2-C3H2C2D_RBX1; modified RING finger, H2 subclass (C3H2C2D-type), found in RING-box protein 1 (RBX1) and similar proteins

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

    Range
    25050324..25064237 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038614415.1XP_038470343.1  E3 ubiquitin-protein ligase RBX1 isoform X2

    Conserved Domains (1) summary
    cl17238
    Location:2076
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
  2. XM_038614414.1XP_038470342.1  E3 ubiquitin-protein ligase RBX1 isoform X1

    Conserved Domains (1) summary
    cd16485
    Location:40101
    mRING-H2-C3H2C2D_RBX1; modified RING finger, H2 subclass (C3H2C2D-type), found in RING-box protein 1 (RBX1) and similar proteins

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

    Range
    25224699..25238847 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038550450.1XP_038406378.1  E3 ubiquitin-protein ligase RBX1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3PFV1, A0A8P0T5W7
    Conserved Domains (1) summary
    cl17238
    Location:2076
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
  2. XM_038550449.1XP_038406377.1  E3 ubiquitin-protein ligase RBX1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0JMB1, A0A8C0T401, A0A8I3NXW3
    Conserved Domains (1) summary
    cd16485
    Location:40101
    mRING-H2-C3H2C2D_RBX1; modified RING finger, H2 subclass (C3H2C2D-type), found in RING-box protein 1 (RBX1) and similar proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    24200859..24214782 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005625839.4XP_005625896.1  E3 ubiquitin-protein ligase RBX1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3PFV1, A0A8P0T5W7
    Conserved Domains (1) summary
    cl17238
    Location:2076
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
  2. XM_531722.7XP_531722.2  E3 ubiquitin-protein ligase RBX1 isoform X1

    See identical proteins and their annotated locations for XP_531722.2

    UniProtKB/TrEMBL
    A0A8C0JMB1, A0A8C0T401, A0A8I3NXW3
    Conserved Domains (1) summary
    cd16485
    Location:40101
    mRING-H2-C3H2C2D_RBX1; modified RING finger, H2 subclass (C3H2C2D-type), found in RING-box protein 1 (RBX1) and similar proteins