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HTR2C 5-hydroxytryptamine receptor 2C [ Pan troglodytes (chimpanzee) ]

Gene ID: 473740, updated on 13-Apr-2024

Summary

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Official Symbol
HTR2Cprovided by VGNC
Official Full Name
5-hydroxytryptamine receptor 2Cprovided by VGNC
Primary source
VGNC:VGNC:7460
Locus tag
CK820_G0034887
See related
Ensembl:ENSPTRG00000022199
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
5-HT2C; 5-HTR2C
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: X
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) X NC_072421.2 (112062892..112387999)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) X NC_072421.1 (112058972..112384079)

Chromosome X - NC_072421.2Genomic Context describing neighboring genes Neighboring gene transportin-3-like Neighboring gene RNA polymerase II subunit A C-terminal domain phosphatase SSU72-like Neighboring gene large ribosomal subunit protein eL42-like Neighboring gene small nucleolar RNA SNORA35 Neighboring gene microRNA mir-764 Neighboring gene microRNA mir-1264 Neighboring gene microRNA mir-1298 Neighboring gene heat shock cognate 71 kDa protein-like Neighboring gene microRNA mir-448 Neighboring gene U6 spliceosomal RNA Neighboring gene interleukin 13 receptor subunit alpha 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Accelerated evolution of nervous system genes in the origin of Homo sapiens. Dorus S, et al. Cell, 2004 Dec 29. PMID 15620360

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled serotonin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neurotransmitter receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in feeding behavior IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in locomotory behavior IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in release of sequestered calcium ion into cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in dendrite IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
5-hydroxytryptamine receptor 2C
Names
5-HT-2C
5-alpha-hydroxytryptamine receptor 2C
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
serotonin receptor 2C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033932.2 → NP_001029104.2  5-hydroxytryptamine receptor 2C precursor

    See identical proteins and their annotated locations for NP_001029104.2

    Status: VALIDATED

    Source sequence(s)
    AY665262, JAQQLN020000024
    UniProtKB/Swiss-Prot
    Q5IS66
    UniProtKB/TrEMBL
    A0A2J8KYJ7, A0A6D2XZA9, H2QZ10
    Conserved Domains (1) summary
    cd15305
    Location:54 → 385
    7tmA_5-HT2C; serotonin receptor subtype 2C, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072421.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    112062892..112387999
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009439546.4 → XP_009437821.2  5-hydroxytryptamine receptor 2C isoform X1

  2. XM_009439547.3 → XP_009437822.2  5-hydroxytryptamine receptor 2C isoform X2

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5IS66.1 GenPept UniProtKB/Swiss-Prot:Q5IS66

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
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