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ALAS2 5'-aminolevulinate synthase 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 473626, updated on 3-Apr-2024

Summary

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Official Symbol
ALAS2provided by VGNC
Official Full Name
5'-aminolevulinate synthase 2provided by VGNC
Primary source
VGNC:VGNC:58107
Locus tag
CK820_G0053279
See related
Ensembl:ENSPTRG00000043518
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: X
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) X NC_072421.2 (55049129..55071074, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) X NC_072421.1 (55045229..55067173, complement)

Chromosome X - NC_072421.2Genomic Context describing neighboring genes Neighboring gene 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 Neighboring gene apurinic/apyrimidinic endodeoxyribonuclease 2 Neighboring gene PAGE family member 2B Neighboring gene putative G antigen family E member 3 Neighboring gene VCP nuclear cofactor family member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5-aminolevulinate synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in erythrocyte development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heme biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hemoglobin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
5-aminolevulinate synthase, erythroid-specific, mitochondrial
Names
aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia)
XP_016799135.1
XP_016799136.1
XP_063660325.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072421.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    55049129..55071074 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016943647.3 → XP_016799136.1  5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A2I3S010, A0A2J8ITN6, A0A6D2W3C9
    Related
    ENSPTRP00000070205.1
    Conserved Domains (2) summary
    TIGR01821
    Location:106 → 511
    5aminolev_synth; 5-aminolevulinic acid synthase
    pfam09029
    Location:5 → 100
    Preseq_ALAS; 5-aminolevulinate synthase presequence

  2. XM_016943646.3 → XP_016799135.1  5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A2I3SJ87, A0A2J8ITQ6, A0A6D2W7T4
    Related
    ENSPTRP00000076950.1
    Conserved Domains (2) summary
    TIGR01821
    Location:143 → 548
    5aminolev_synth; 5-aminolevulinic acid synthase
    pfam09029
    Location:5 → 100
    Preseq_ALAS; 5-aminolevulinate synthase presequence

  3. XM_063804255.1 → XP_063660325.1  5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A2I3SG56, A0A2J8ITP2, A0A6D2Y472
Nucleotide Protein
Heading Accession and Version

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