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KRAS KRAS proto-oncogene, GTPase [ Pan troglodytes (chimpanzee) ]

Gene ID: 473387, updated on 3-Apr-2024

Summary

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Official Symbol
KRASprovided by VGNC
Official Full Name
KRAS proto-oncogene, GTPaseprovided by VGNC
Primary source
VGNC:VGNC:10375
Locus tag
CK820_G0019038
See related
Ensembl:ENSPTRG00000004775
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See KRAS in Genome Data Viewer
Location:
chromosome: 12
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 10 NC_072408.2 (70289890..70335681)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 12 NC_072410.1 (68913665..68959335)

Chromosome 10 - NC_072408.2Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene uncharacterized LOC134807482 Neighboring gene uncharacterized LOC134807484 Neighboring gene electron transfer flavoprotein regulatory factor 1 Neighboring gene dynein axonemal intermediate chain 7 Neighboring gene centromere protein U-like Neighboring gene inositol 1,4,5-triphosphate receptor associated 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GDP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
GTPase KRas
Names
Kirsten rat sarcoma viral oncogene homolog
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
XP_003313842.1
XP_009423991.1
XP_054520426.1
XP_528758.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072408.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    70289890..70335681
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_528758.9 → XP_528758.3  GTPase KRas isoform X2

    See identical proteins and their annotated locations for XP_528758.3

    UniProtKB/TrEMBL
    A0A2J8QR28, A0A6D2X9U3, H2Q5M0, H2Q5M1
    Related
    ENSPTRP00000008149.3
    Conserved Domains (1) summary
    cd04138
    Location:3 → 164
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B

  2. XM_054664451.2 → XP_054520426.1  GTPase KRas isoform X2

    UniProtKB/TrEMBL
    A0A2J8QR28, A0A6D2X9U3, H2Q5M0

  3. XM_009425716.5 → XP_009423991.1  GTPase KRas isoform X1

    See identical proteins and their annotated locations for XP_009423991.1

    UniProtKB/TrEMBL
    A0A2I3T6U4, A0A2J8QR25, A0A6D2WV88, H2Q5M1
    Related
    ENSPTRP00000084588.1
    Conserved Domains (1) summary
    cd04138
    Location:3 → 164
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B

  4. XM_003313794.7 → XP_003313842.1  GTPase KRas isoform X1

    See identical proteins and their annotated locations for XP_003313842.1

    UniProtKB/TrEMBL
    A0A2I3T6U4, A0A2J8QR25, A0A6D2WV88, H2Q5M1
    Conserved Domains (1) summary
    cd04138
    Location:3 → 164
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B
Nucleotide Protein
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