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HRH2 histamine receptor H2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 471750, updated on 29-Mar-2024

Summary

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Official Symbol
HRH2provided by VGNC
Official Full Name
histamine receptor H2provided by VGNC
Primary source
VGNC:VGNC:4039
Locus tag
CK820_G0025690
See related
Ensembl:ENSPTRG00000017551
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 4 NC_072402.2 (173315872..173368546)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 5 NC_072403.1 (173332863..173385482)

Chromosome 4 - NC_072402.2Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene sideroflexin 1 Neighboring gene U6 spliceosomal RNA Neighboring gene complexin 2 Neighboring gene THO complex subunit 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled serotonin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histamine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neurotransmitter receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in gastric acid secretion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of vasoconstriction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in dendrite IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histamine H2 receptor
Names
H2R
HH2R
gastric receptor I

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009124.1 → NP_001009124.1  histamine H2 receptor

    See identical proteins and their annotated locations for NP_001009124.1

    Status: PROVISIONAL

    Source sequence(s)
    AB041385
    UniProtKB/Swiss-Prot
    P60021
    UniProtKB/TrEMBL
    A0A2J8LXU0
    Conserved Domains (1) summary
    cd15051
    Location:19 → 299
    7tmA_Histamine_H2R; histamine subtype H2 receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    173315872..173368546
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054684081.2 → XP_054540056.1  histamine H2 receptor isoform X2

    UniProtKB/TrEMBL
    A0A2J8LXR9, A0A2K6I1Z4, A0A6D2WVY6

  2. XM_009450086.4 → XP_009448361.1  histamine H2 receptor isoform X1

    See identical proteins and their annotated locations for XP_009448361.1

    UniProtKB/TrEMBL
    A0A2I3RKF1, A0A2I3RRR1, A0A2J8LXJ1, A0A6D2XHK0
    Related
    ENSPTRP00000065133.1
    Conserved Domains (1) summary
    cd15051
    Location:19 → 299
    7tmA_Histamine_H2R; histamine subtype H2 receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_009450087.5 → XP_009448362.1  histamine H2 receptor isoform X1

    See identical proteins and their annotated locations for XP_009448362.1

    UniProtKB/TrEMBL
    A0A2I3RKF1, A0A2I3RRR1, A0A2J8LXJ1, A0A6D2XHK0
    Conserved Domains (1) summary
    cd15051
    Location:19 → 299
    7tmA_Histamine_H2R; histamine subtype H2 receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

RNA

  1. XR_010156807.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P60021.1 GenPept UniProtKB/Swiss-Prot:P60021

Gene LinkOut

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