IL12B interleukin 12B [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: IL12Bprovided by VGNC
Official Full Name: interleukin 12Bprovided by VGNC
Primary source: VGNC:VGNC:4041
Locus tag: CK820_G0010230
See related: Ensembl:ENSPTRG00000017481
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	4	NC_072402.2 (157008093..157024690, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	5	NC_072403.1 (157028992..157045614, complement)

Chromosome 4 - NC_072402.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

G10637 (e-PCR)
- UniSTS:60436

SGC35786 (e-PCR)
- UniSTS:51991

NoName (e-PCR)
- UniSTS:480804

RH17728 (e-PCR)
- UniSTS:24645

NoName (e-PCR)
- UniSTS:481890

IL12B_146 (e-PCR)
- UniSTS:277362

PMC321570P1 (e-PCR)
- UniSTS:273112

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cytokine receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: interleukin-12 subunit beta

Names: interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

157008093..157024690 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_527101.8 → XP_527101.2 interleukin-12 subunit beta

UniProtKB/TrEMBL

A0A2J8NKD7, A0A6D2W675, H2QRX3

Conserved Domains (3) summary

smart00408
Location:42 → 90

IGc2; Immunoglobulin C-2 Type

cd00063
Location:235 → 325

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam10420
Location:126 → 216

IL12p40_C; Cytokine interleukin-12p40 C-terminus