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CSF2 colony stimulating factor 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 471627, updated on 29-Mar-2024

Summary

Official Symbol
CSF2provided by VGNC
Official Full Name
colony stimulating factor 2provided by VGNC
Primary source
VGNC:VGNC:6847
Locus tag
CK820_G0026794
See related
Ensembl:ENSPTRG00000017212
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

Location:
chromosome: 5
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 4 NC_072402.2 (129837842..129840222)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 5 NC_072403.1 (129856403..129858783)

Chromosome 4 - NC_072402.2Genomic Context describing neighboring genes Neighboring gene acyl-CoA synthetase long chain family member 6 Neighboring gene interleukin 3 Neighboring gene prolyl 4-hydroxylase subunit alpha 2 Neighboring gene short transmembrane mitochondrial protein 1-like Neighboring gene PDZ and LIM domain 4

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables granulocyte macrophage colony-stimulating factor receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in immune response IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in myeloid cell differentiation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
granulocyte-macrophage colony-stimulating factor
Names
colony stimulating factor 2 (granulocyte-macrophage)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    129837842..129840222
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_527005.4XP_527005.2  granulocyte-macrophage colony-stimulating factor

    See identical proteins and their annotated locations for XP_527005.2

    UniProtKB/TrEMBL
    A0A2J8LS57, A0A6D2X6Y2, H2QRG1
    Related
    ENSPTRP00000029448.1
    Conserved Domains (1) summary
    cd00040
    Location:18138
    CSF2; Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) is a member of the large family of polypeptide growth factors called cytokines. It stimulates a wide variety of hematopoietic and nonhematopoietic cell types via binding to members of the cytokine ...