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SKP2 S-phase kinase associated protein 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 471570, updated on 29-Mar-2024

Summary

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Official Symbol
SKP2provided by VGNC
Official Full Name
S-phase kinase associated protein 2provided by VGNC
Primary source
VGNC:VGNC:14453
Locus tag
CK820_G0044881
See related
Ensembl:ENSPTRG00000016797
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 4 NC_072402.2 (76592446..76633141, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 5 NC_072403.1 (76780201..76821668, complement)

Chromosome 4 - NC_072402.2Genomic Context describing neighboring genes Neighboring gene RAN binding protein 3 like Neighboring gene NAD kinase 2, mitochondrial Neighboring gene U6 spliceosomal RNA Neighboring gene LMBR1 domain containing 2 Neighboring gene microRNA mir-580 Neighboring gene UDP glycosyltransferase family 3 member A2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G2/M transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
S-phase kinase-associated protein 2
Names
S-phase kinase-associated protein 2 (p45)
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    76592446..76633141 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024356632.3 → XP_024212400.1  S-phase kinase-associated protein 2 isoform X3

    UniProtKB/TrEMBL
    H2QQS0
    Conserved Domains (3) summary
    sd00034
    Location:183 → 207
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:97 → 141
    F-box-like
    cl28166
    Location:193 → 359
    AMN1; Antagonist of mitotic exit network protein 1

  2. XM_016953422.2 → XP_016808911.1  S-phase kinase-associated protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A2J8JS94, A0A8I3B3F3, H2QQS0, K6ZLS5, K7BZX2
    Conserved Domains (3) summary
    cd09293
    Location:193 → 345
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:183 → 207
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:97 → 141
    F-box-like

  3. XM_526948.8 → XP_526948.2  S-phase kinase-associated protein 2 isoform X1

    See identical proteins and their annotated locations for XP_526948.2

    UniProtKB/TrEMBL
    A0A2I3RFB4, A0A2J8JSD0, A0A6D2WES0, H2QQS0
    Related
    ENSPTRP00000063321.1
    Conserved Domains (3) summary
    cd09293
    Location:193 → 345
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:183 → 207
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:97 → 141
    F-box-like

  4. XM_063811303.1 → XP_063667373.1  S-phase kinase-associated protein 2 isoform X4

RNA

  1. XR_680222.3 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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