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CISH cytokine inducible SH2 containing protein [ Pan troglodytes (chimpanzee) ]

Gene ID: 470819, updated on 29-Mar-2024

Summary

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Official Symbol
CISHprovided by VGNC
Official Full Name
cytokine inducible SH2 containing proteinprovided by VGNC
Primary source
VGNC:VGNC:9659
Locus tag
CK820_G0005034
See related
Ensembl:ENSPTRG00000014967
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 2 NC_086015.1 (54635279..54640629, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 3 NC_072401.1 (54634948..54640298, complement)

Chromosome 2 - NC_086015.1Genomic Context describing neighboring genes Neighboring gene chromosome 3 C3orf18 homolog Neighboring gene HemK methyltransferase family member 1 Neighboring gene uncharacterized LOC104005567 Neighboring gene MAPK activated protein kinase 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cytokine-inducible SH2-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_086015.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    54635279..54640629 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003309810.3 → XP_003309858.1  cytokine-inducible SH2-containing protein isoform X2

    UniProtKB/TrEMBL
    A0A2I3T047, A0A2J8P8S2, A0A2J8P8V3, A0A6D2W8S1, A0A6D2XZB0, H2QMP4
    Related
    ENSPTRP00000025840.3
    Conserved Domains (2) summary
    cd10718
    Location:77 → 164
    SH2_CIS; Src homology 2 (SH2) domain found in cytokine-inducible SH2-containing protein (CIS)
    cd03734
    Location:218 → 258
    SOCS_CIS1; SOCS (suppressors of cytokine signaling) box of CIS (cytokine-inducible SH2 protein) 1-like proteins. Together with the SOCS proteins, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. ...

  2. XM_016941171.2 → XP_016796660.1  cytokine-inducible SH2-containing protein isoform X1

    UniProtKB/TrEMBL
    A0A2I3T047, A0A2J8P8V3, A0A6D2XZB0
Nucleotide Protein
Heading Accession and Version

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