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THRB thyroid hormone receptor beta [ Pan troglodytes (chimpanzee) ]

Gene ID: 470771, updated on 3-Apr-2024

Summary

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Official Symbol
THRBprovided by VGNC
Official Full Name
thyroid hormone receptor betaprovided by VGNC
Primary source
VGNC:VGNC:8014
Locus tag
CK820_G0008908
See related
Ensembl:ENSPTRG00000014697
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 2 NC_086015.1 (28104651..28481514, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 3 NC_072401.1 (28104320..28481182, complement)

Chromosome 2 - NC_086015.1Genomic Context describing neighboring genes Neighboring gene nucleophosmin-like Neighboring gene uncharacterized LOC100614625 Neighboring gene uncharacterized LOC107970586 Neighboring gene uncharacterized LOC129143484 Neighboring gene eukaryotic translation initiation factor 3 subunit K-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in retinoic acid receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in thyroid hormone mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
thyroid hormone receptor beta
Names
thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_086015.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    28104651..28481514 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016940582.3 → XP_016796071.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2I3S9V4, A0A2J8NPI4, A0A6D2WCL4, H2R3K3
    Related
    ENSPTRP00000045665.3
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  2. XM_054680443.1 → XP_054536418.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2J8NPI4, A0A6D2WCL4, H2R3K3

  3. XM_054680441.1 → XP_054536416.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2J8NPI4, A0A6D2WCL4, H2R3K3

  4. XM_063806667.1 → XP_063662737.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2J8NPI4, A0A6D2WCL4, H2R3K3

  5. XM_054680440.2 → XP_054536415.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2J8NPI4, A0A6D2WCL4, H2R3K3

  6. XM_016940578.4 → XP_016796067.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2I3S9V4, A0A2J8NPI4, A0A6D2WCL4, H2R3K3
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  7. XM_016940574.4 → XP_016796063.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2I3S9V4, A0A2J8NPI4, A0A6D2WCL4, H2R3K3
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  8. XM_054680445.2 → XP_054536420.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2J8NPI4, A0A6D2WCL4, H2R3K3

  9. XM_001164073.8 → XP_001164073.1  thyroid hormone receptor beta isoform X2

    See identical proteins and their annotated locations for XP_001164073.1

    UniProtKB/TrEMBL
    A0A2I3S9V4, A0A2J8NPI4, A0A6D2WCL4, H2R3K3
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  10. XM_054680439.2 → XP_054536414.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2J8NPI4, A0A6D2WCL4, H2R3K3

  11. XM_054680442.2 → XP_054536417.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2J8NPI4, A0A6D2WCL4, H2R3K3

  12. XM_063806666.1 → XP_063662736.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2J8NPI4, A0A6D2WCL4, H2R3K3

  13. XM_054680444.2 → XP_054536419.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2J8NPI4, A0A6D2WCL4, H2R3K3

  14. XM_016940570.4 → XP_016796059.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2I3S9V4, A0A2J8NPI4, A0A6D2WCL4, H2R3K3
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  15. XM_016940577.4 → XP_016796066.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2I3S9V4, A0A2J8NPI4, A0A6D2WCL4, H2R3K3
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  16. XM_016940573.4 → XP_016796062.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2I3S9V4, A0A2J8NPI4, A0A6D2WCL4, H2R3K3
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  17. XM_009445027.5 → XP_009443302.1  thyroid hormone receptor beta isoform X2

    See identical proteins and their annotated locations for XP_009443302.1

    UniProtKB/TrEMBL
    A0A2I3S9V4, A0A2J8NPI4, A0A6D2WCL4, H2R3K3
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  18. XM_016940571.4 → XP_016796060.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2I3S9V4, A0A2J8NPI4, A0A6D2WCL4, H2R3K3
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  19. XM_016940581.4 → XP_016796070.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2I3S9V4, A0A2J8NPI4, A0A6D2WCL4, H2R3K3
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  20. XM_016940576.4 → XP_016796065.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2I3S9V4, A0A2J8NPI4, A0A6D2WCL4, H2R3K3
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  21. XM_001164153.6 → XP_001164153.1  thyroid hormone receptor beta isoform X2

    See identical proteins and their annotated locations for XP_001164153.1

    UniProtKB/TrEMBL
    A0A2I3S9V4, A0A2J8NPI4, A0A6D2WCL4, H2R3K3
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  22. XM_016940583.4 → XP_016796072.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2I3S9V4, A0A2J8NPI4, A0A6D2WCL4, H2R3K3
    Conserved Domains (2) summary
    cd06935
    Location:216 → 458
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:106 → 192
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers

  23. XM_063806668.1 → XP_063662738.1  thyroid hormone receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2J8NPI4, A0A6D2WCL4, H2R3K3

  24. XM_009445025.5 → XP_009443300.1  thyroid hormone receptor beta isoform X1

    See identical proteins and their annotated locations for XP_009443300.1

    UniProtKB/TrEMBL
    A0A2I3SVN9, A0A2J8NPI8, A0A6D2Y4T7
    Related
    ENSPTRP00000080632.1
    Conserved Domains (2) summary
    cd06935
    Location:231 → 473
    NR_LBD_TR; The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors
    cd06961
    Location:121 → 207
    NR_DBD_TR; DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers
Nucleotide Protein
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