HRH1 histamine receptor H1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: HRH1provided by VGNC
Official Full Name: histamine receptor H1provided by VGNC
Primary source: VGNC:VGNC:1838
Locus tag: CK820_G0025262
See related: Ensembl:ENSPTRG00000030304
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	2	NC_086015.1 (15157245..15283082)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	3	NC_072401.1 (15156918..15282755)

Chromosome 2 - NC_086015.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

D10S275 (e-PCR)
- UniSTS:147992

D3S3461 (e-PCR)
- UniSTS:153907

SHGC-132075 (e-PCR)
- UniSTS:173890

HRH1_1003 (e-PCR)
- UniSTS:277327

HRH1_V259 (e-PCR)
- UniSTS:277327

RH69713 (e-PCR)
- UniSTS:42320

SHGC-148056 (e-PCR)
- UniSTS:172921

D3S4194 (e-PCR)
- UniSTS:2436

D3S3145 (e-PCR)
- UniSTS:37830

SHGC-76733 (e-PCR)
- UniSTS:67288

RH36646 (e-PCR)
- UniSTS:85732

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables G protein-coupled serotonin receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables histamine receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables neurotransmitter receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	IEA Inferred from Electronic Annotation more info	PubMed
involved_in chemical synaptic transmission	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of vasoconstriction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of vascular permeability	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in dendrite	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: histamine H1 receptor

Names: H1R; HH1R

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001114165.1 → NP_001107637.1 histamine H1 receptor

See identical proteins and their annotated locations for NP_001107637.1

Status: PROVISIONAL

Source sequence(s)

AB041381

UniProtKB/Swiss-Prot

Q9N2B2

UniProtKB/TrEMBL

H2R8F8

Related

ENSPTRP00000051571.3, ENSPTRT00000058556.4

Conserved Domains (2) summary

pfam00001
Location:45 → 220

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:34 → 162

7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_086015.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

15157245..15283082

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016940006.3 → XP_016795495.2 histamine H1 receptor isoform X1

UniProtKB/TrEMBL

A0A2J8M1B5, A0A803KI87, H2R8F8, K7CQF5

Conserved Domains (1) summary

cd15050
Location:28 → 479

7tmA_Histamine_H1R; histamine subtype H1 receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
XM_016940001.3 → XP_016795490.2 histamine H1 receptor isoform X1

UniProtKB/TrEMBL

A0A2J8M1B5, A0A803KI87, H2R8F8, K7CQF5

Conserved Domains (1) summary

cd15050
Location:28 → 479

7tmA_Histamine_H1R; histamine subtype H1 receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
XM_016940003.3 → XP_016795492.2 histamine H1 receptor isoform X1

UniProtKB/TrEMBL

A0A2J8M1B5, A0A803KI87, H2R8F8, K7CQF5

Conserved Domains (1) summary

cd15050
Location:28 → 479

7tmA_Histamine_H1R; histamine subtype H1 receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
XM_016940002.3 → XP_016795491.2 histamine H1 receptor isoform X1

UniProtKB/TrEMBL

A0A2J8M1B5, A0A803KI87, H2R8F8, K7CQF5

Conserved Domains (1) summary

cd15050
Location:28 → 479

7tmA_Histamine_H1R; histamine subtype H1 receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
XM_063805262.1 → XP_063661332.1 histamine H1 receptor isoform X1

UniProtKB/TrEMBL

A0A2J8M1B5, A0A803KI87, K7CQF5
XM_016940004.4 → XP_016795493.2 histamine H1 receptor isoform X1

UniProtKB/TrEMBL

A0A2J8M1B5, A0A803KI87, H2R8F8, K7CQF5

Conserved Domains (1) summary

cd15050
Location:28 → 479

7tmA_Histamine_H1R; histamine subtype H1 receptor, member of the class A family of seven-transmembrane G protein-coupled receptors