INPP5D inositol polyphosphate-5-phosphatase D [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: INPP5Dprovided by VGNC
Official Full Name: inositol polyphosphate-5-phosphatase Dprovided by VGNC
Primary source: VGNC:VGNC:50731
Locus tag: CK820_G0010809
See related: Ensembl:ENSPTRG00000013050
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2B

Exon count:: 28

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	13	NC_072411.2 (135264338..135413363)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	2B	NC_072400.1 (135175573..135324523)

Chromosome 13 - NC_072411.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

G29434 (e-PCR)
- UniSTS:10754

SHGC-142327 (e-PCR)
- UniSTS:171392

INPP5D_160 (e-PCR)
- UniSTS:277386

RH68049 (e-PCR)
- UniSTS:63658

SHGC-61987 (e-PCR)
- UniSTS:39880

RH68337 (e-PCR)
- UniSTS:6352

RH70363 (e-PCR)
- UniSTS:47598

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of bone resorption	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of neutrophil differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in phosphatidylinositol dephosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of B cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of immune response	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

Names: SH2 containing inositol phosphatase; inositol polyphosphate-5-phosphatase, 145kDa

XP_016806215.2

EC 3.1.3.86

XP_016806216.2

EC 3.1.3.86

XP_016806217.2

EC 3.1.3.86

XP_063646949.1

EC 3.1.3.86

XP_063646950.1

EC 3.1.3.86

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072411.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

135264338..135413363

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016950726.3 → XP_016806215.2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1
XM_016950727.3 → XP_016806216.2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X2
XM_063790880.1 → XP_063646950.1 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X4
XM_063790879.1 → XP_063646949.1 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X3
XM_016950728.3 → XP_016806217.2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X5