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ITGA4 integrin subunit alpha 4 [ Pan troglodytes (chimpanzee) ]

Gene ID: 470596, updated on 3-Apr-2024

Summary

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Official Symbol
ITGA4provided by VGNC
Official Full Name
integrin subunit alpha 4provided by VGNC
Primary source
VGNC:VGNC:2704
Locus tag
CK820_G0001660
See related
Ensembl:ENSPTRG00000012700
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2B
Exon count:
38
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 13 NC_072411.2 (83160266..83572533)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2B NC_072400.1 (83492180..83573854)

Chromosome 13 - NC_072411.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134807995 Neighboring gene uncharacterized LOC134807996 Neighboring gene ceramide kinase like Neighboring gene neuronal differentiation 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
integrin alpha-4
Names
integrin alpha 4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072411.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    83160266..83572533
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063790615.1 → XP_063646685.1  integrin alpha-4 isoform X2

  2. XM_063790617.1 → XP_063646687.1  integrin alpha-4 isoform X4

    UniProtKB/TrEMBL
    A0A2J8PRK0, A0A6D2WR60, H2QJ29

  3. XM_063790618.1 → XP_063646688.1  integrin alpha-4 isoform X4

    UniProtKB/TrEMBL
    A0A2J8PRK0, A0A6D2WR60, H2QJ29

  4. XM_016950124.3 → XP_016805613.1  integrin alpha-4 isoform X4

    UniProtKB/TrEMBL
    A0A2I3TLT4, A0A2J8PRK0, A0A6D2WR60, H2QJ29
    Related
    ENSPTRP00000021717.5
    Conserved Domains (2) summary
    smart00191
    Location:366 → 418
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam08441
    Location:463 → 902
    Integrin_alpha2; Integrin alpha

  5. XM_063790616.1 → XP_063646686.1  integrin alpha-4 isoform X3

  6. XM_063790614.1 → XP_063646684.1  integrin alpha-4 isoform X1

  7. XM_063790619.1 → XP_063646689.1  integrin alpha-4 isoform X4

    UniProtKB/TrEMBL
    A0A2J8PRK0, A0A6D2WR60, H2QJ29

  8. XM_063790620.1 → XP_063646690.1  integrin alpha-4 isoform X5

  9. XM_063790621.1 → XP_063646691.1  integrin alpha-4 isoform X5

RNA

  1. XR_010149805.1 RNA Sequence

  2. XR_010149806.1 RNA Sequence

  3. XR_010149807.1 RNA Sequence

  4. XR_010149811.1 RNA Sequence

  5. XR_010149808.1 RNA Sequence

  6. XR_010149812.1 RNA Sequence

  7. XR_010149809.1 RNA Sequence

  8. XR_010149810.1 RNA Sequence

Nucleotide Protein
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