GNAS GNAS complex locus [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: GNASprovided by VGNC
Official Full Name: GNAS complex locusprovided by VGNC
Primary source: VGNC:VGNC:57986
Locus tag: CK820_G0037167
See related: Ensembl:ENSPTRG00000032488
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	21	NC_072419.2 (65136150..65206823)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	20	NC_072418.1 (65191641..65262314)

Chromosome 21 - NC_072419.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

GDB:393268 (e-PCR)
- UniSTS:157191

WI-18315 (e-PCR)
- UniSTS:36377

GNAS1 (e-PCR)
- UniSTS:253722

RH47664 (e-PCR)
- UniSTS:37659

PMC182207P1 (e-PCR)
- UniSTS:271678

STS-M21142 (e-PCR)
- UniSTS:32343

PMC301417P1 (e-PCR)
- UniSTS:272476

PMC301417P2 (e-PCR)
- UniSTS:272477

D20S459 (e-PCR)
- UniSTS:4202

RH75699 (e-PCR)
- UniSTS:85118

WI-11711 (e-PCR)
- UniSTS:14977

GNAS_3080 (e-PCR)
- UniSTS:462216

SHGC-60147 (e-PCR)
- UniSTS:18828

Gnas (e-PCR), detects polymorphism
- UniSTS:186518

SHGC-59923 (e-PCR)
- UniSTS:54725

RH98861 (e-PCR)
- UniSTS:84942

SHGC-58255 (e-PCR)
- UniSTS:80093

MARC_5561-5562:1031675650:1 (e-PCR)
- UniSTS:269538

GDB:180724 (e-PCR)
- UniSTS:155110

PMC22380P2 (e-PCR)
- UniSTS:272105

D20S541E (e-PCR)
- UniSTS:150765

RH68035 (e-PCR)
- UniSTS:34034

RH11717 (e-PCR)
- UniSTS:46841

RH93711 (e-PCR)
- UniSTS:88575

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables D1 dopamine receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables G-protein beta/gamma-subunit complex binding	IEA Inferred from Electronic Annotation more info	PubMed
enables GTP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables beta-2 adrenergic receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables corticotropin-releasing hormone receptor 1 binding	IEA Inferred from Electronic Annotation more info	PubMed
enables insulin-like growth factor receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ionotropic glutamate receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables mu-type opioid receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in adenylate cyclase-activating dopamine receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in sensory perception of chemical stimulus	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of heterotrimeric G-protein complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: guanine nucleotide-binding protein G(s) subunit alpha

Names: guanine nucleotide binding protein, alpha stimulating activity polypeptide 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072419.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

65136150..65206823

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009437483.4 → XP_009435758.1 guanine nucleotide-binding protein G(s) subunit alpha isoform X4

See identical proteins and their annotated locations for XP_009435758.1

UniProtKB/TrEMBL

A0A2J8KMP2

Related

ENSPTRP00000065323.1

Conserved Domains (1) summary

cd00066
Location:5 → 356

G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)
XM_009437485.4 → XP_009435760.1 guanine nucleotide-binding protein G(s) subunit alpha isoform X6

See identical proteins and their annotated locations for XP_009435760.1

UniProtKB/TrEMBL

A0A2J8KMP2

Conserved Domains (1) summary

cd00066
Location:5 → 341

G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)
XM_016938188.4 → XP_016793677.1 guanine nucleotide-binding protein G(s) subunit alpha isoform X5

UniProtKB/TrEMBL

A0A2J8KMP2

Conserved Domains (1) summary

cd00066
Location:5 → 342

G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)
XM_024352038.3 → XP_024207806.1 guanine nucleotide-binding protein G(s) subunit alpha isoform X8

UniProtKB/TrEMBL

A0A2J8KMN5

Conserved Domains (1) summary

smart00275
Location:20 → 71

G_alpha; G protein alpha subunit
XM_016938189.4 → XP_016793678.2 guanine nucleotide-binding protein G(s) subunit alpha isoform X1

UniProtKB/TrEMBL

A0A2I3S3X1, A0A2J8KMM8

Conserved Domains (1) summary

cd00066
Location:41 → 388

G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)
XM_016938193.4 → XP_016793682.2 guanine nucleotide-binding protein G(s) subunit alpha isoform X3

UniProtKB/TrEMBL

A0A2I3S3X1, A0A2J8KMN8

Conserved Domains (1) summary

cd00066
Location:41 → 373

G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)
XM_024352037.3 → XP_024207805.1 guanine nucleotide-binding protein G(s) subunit alpha isoform X2

UniProtKB/TrEMBL

A0A2I3S3X1, A0A2J8KMN4

Conserved Domains (1) summary

cd00066
Location:41 → 374

G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)
XM_063802685.1 → XP_063658755.1 guanine nucleotide-binding protein G(s) subunit alpha isoform X7