IL10 interleukin 10 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: IL10provided by VGNC
Official Full Name: interleukin 10provided by VGNC
Primary source: VGNC:VGNC:52981
Locus tag: CK820_G0012800
See related: Ensembl:ENSPTRG00000001916
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as: IF2A
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	1	NC_072398.2 (42312894..42319869)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	1	NC_072398.1 (189003481..189010456, complement)

Chromosome 1 - NC_072398.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

IL10 (e-PCR), detects polymorphism
- UniSTS:479745

SHGC-76259 (e-PCR)
- UniSTS:13362

AL034234 (e-PCR)
- UniSTS:94051

AL009920 (e-PCR)
- UniSTS:65648

PMC18942P1 (e-PCR)
- UniSTS:271741

IL10 (e-PCR), detects polymorphism
- UniSTS:264070

PMC112029P1 (e-PCR)
- UniSTS:270225

Il10 (e-PCR), detects polymorphism
- UniSTS:143532

GDB:603928 (e-PCR)
- UniSTS:158199

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cytokine activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: interleukin-10

Names: CSIF; IL-10; cytokine synthesis inhibitory factor; interferon 2A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001135620.2 → NP_001129092.2 interleukin-10 precursor

See identical proteins and their annotated locations for NP_001129092.2

Status: VALIDATED

Source sequence(s)

JAQQLN020000001

UniProtKB/Swiss-Prot

A2T6Z6

UniProtKB/TrEMBL

A0A2J8QVU1, A0A6D2X2D2, H2Q105

Conserved Domains (1) summary

pfam00726
Location:5 → 174

IL10; Interleukin 10

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

42312894..42319869

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016927617.2 → XP_016783106.1 interleukin-10 isoform X2

UniProtKB/Swiss-Prot

A2T6Z6

UniProtKB/TrEMBL

A0A2J8QVU1, A0A6D2X2D2, H2Q105

Related

ENSPTRP00000003208.1

Conserved Domains (1) summary

pfam00726
Location:5 → 174

IL10; Interleukin 10
XM_063798179.1 → XP_063654249.1 interleukin-10 isoform X1