FASLG Fas ligand [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: FASLGprovided by VGNC
Official Full Name: Fas ligandprovided by VGNC
Primary source: VGNC:VGNC:6816
Locus tag: CK820_G0048995
See related: Ensembl:ENSPTRG00000001690
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	1	NC_072398.2 (76432631..76440527, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	1	NC_072398.1 (154909221..154917100)

Chromosome 1 - NC_072398.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

D1S3717 (e-PCR)
- UniSTS:10533

TNFSF6_2403 (e-PCR)
- UniSTS:463924

PMC86001P1 (e-PCR)
- UniSTS:273502

PMC86001P2 (e-PCR)
- UniSTS:273503

PMC135646P4 (e-PCR)
- UniSTS:270768

D1S3209 (e-PCR)
- UniSTS:75969

G42266 (e-PCR)
- UniSTS:93939

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables tumor necrosis factor receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in extrinsic apoptotic signaling pathway via death domain receptors	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of canonical NF-kappaB signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: tumor necrosis factor ligand superfamily member 6

Names: Fas ligand (TNF superfamily, member 6)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

76432631..76440527 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_524967.7 → XP_524967.2 tumor necrosis factor ligand superfamily member 6

See identical proteins and their annotated locations for XP_524967.2

UniProtKB/TrEMBL

A0A2J8JBX5, A0A6D2XVD6, H2Q0M2

Related

ENSPTRP00000002815.3

Conserved Domains (1) summary

cd00184
Location:145 → 278

TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...