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NGF nerve growth factor [ Pan troglodytes (chimpanzee) ]

Gene ID: 469423, updated on 11-Apr-2024

Summary

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Official Symbol
NGFprovided by VGNC
Official Full Name
nerve growth factorprovided by VGNC
Primary source
VGNC:VGNC:8424
Locus tag
CK820_G0044941
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
NGFB; beta-NGF
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (112514197..112567503, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (118782228..118835542)

Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene tetraspanin 2 Neighboring gene uncharacterized LOC107967857 Neighboring gene uncharacterized LOC104002213 Neighboring gene uncharacterized LOC107967856 Neighboring gene elongin-C-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Accelerated evolution of nervous system genes in the origin of Homo sapiens. Dorus S, et al. Cell, 2004 Dec 29. PMID 15620360

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nerve growth factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in memory IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in modulation of chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of neuron apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nerve development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nerve growth factor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuron projection morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peripheral nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of collateral sprouting IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendrite IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synaptic vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
beta-nerve growth factor
Names
nerve growth factor (beta polypeptide)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012437.1 → NP_001012439.1  beta-nerve growth factor precursor

    See identical proteins and their annotated locations for NP_001012439.1

    Status: PROVISIONAL

    Source sequence(s)
    AY665265
    UniProtKB/Swiss-Prot
    Q5IS63, Q8HZH3, Q9N2F1
    UniProtKB/TrEMBL
    A0A2J8JRV8, A0A8I3B107, K7ALZ0, K7B794, K7D217
    Conserved Domains (1) summary
    pfam00243
    Location:128 → 237
    NGF; Nerve growth factor family

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    112514197..112567503 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063797813.1 → XP_063653883.1  beta-nerve growth factor isoform X1

    UniProtKB/Swiss-Prot
    Q5IS63, Q8HZH3, Q9N2F1
    UniProtKB/TrEMBL
    K7ALZ0

  2. XM_009428071.5 → XP_009426346.3  beta-nerve growth factor isoform X1

    UniProtKB/Swiss-Prot
    Q5IS63, Q8HZH3, Q9N2F1
    UniProtKB/TrEMBL
    K7ALZ0
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9N2F1.2 GenPept UniProtKB/Swiss-Prot:Q9N2F1

Gene LinkOut

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