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PTCH2 patched 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 469185, updated on 3-Apr-2024

Summary

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Official Symbol
PTCH2provided by VGNC
Official Full Name
patched 2provided by VGNC
Primary source
VGNC:VGNC:1477
Locus tag
CK820_G0025609
See related
Ensembl:ENSPTRG00000000664
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (186123246..186144619)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (45154683..45178617, complement)

Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene peptidyl-prolyl cis-trans isomerase A-like Neighboring gene eukaryotic translation initiation factor 2B subunit gamma Neighboring gene E3 ubiquitin-protein ligase CCNB1IP1-like Neighboring gene U5 spliceosomal RNA Neighboring gene BTB domain containing 19

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hedgehog family protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hedgehog receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables smoothened binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of smoothened signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein patched homolog 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    186123246..186144619
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016961510.3 → XP_016816999.1  protein patched homolog 2 isoform X2

    UniProtKB/TrEMBL
    A0A2I3S0F6, A0A2J8LZU8, A0A2J8LZX6, A0A6D2W9H8, A0A6D2WN89, H2PYW7
    Related
    ENSPTRP00000070340.1
    Conserved Domains (1) summary
    TIGR00918
    Location:12 → 1142
    2A060602; The Eukaryotic (Putative) Sterol Transporter (EST) Family

  2. XM_016961502.4 → XP_016816991.1  protein patched homolog 2 isoform X1

    UniProtKB/TrEMBL
    A0A2J8LZX6, A0A6D2WN89, H2PYW7

  3. XM_054666389.2 → XP_054522364.1  protein patched homolog 2 isoform X5

  4. XM_016961518.4 → XP_016817007.1  protein patched homolog 2 isoform X3

    UniProtKB/TrEMBL
    A0A2J8LZX6, A0A6D2WN89, H2PYW7

  5. XM_016961525.4 → XP_016817014.1  protein patched homolog 2 isoform X4

    UniProtKB/TrEMBL
    A0A2J8LZX6, A0A6D2WN89, H2PYW7
Nucleotide Protein
Heading Accession and Version

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