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NUMBL NUMB like endocytic adaptor protein [ Pan troglodytes (chimpanzee) ]

Gene ID: 468884, updated on 3-Apr-2024

Summary

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Official Symbol
NUMBLprovided by VGNC
Official Full Name
NUMB like endocytic adaptor proteinprovided by VGNC
Primary source
VGNC:VGNC:10250
Locus tag
CK820_G0030474
See related
Ensembl:ENSPTRG00000011003
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 20 NC_072418.2 (43751314..43776331, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 19 NC_072417.1 (43751339..43776356, complement)

Chromosome 20 - NC_072418.2Genomic Context describing neighboring genes Neighboring gene SH3KBP1 binding protein 1 Neighboring gene latent transforming growth factor beta binding protein 4 Neighboring gene coenzyme Q8B Neighboring gene U6 spliceosomal RNA Neighboring gene inositol-trisphosphate 3-kinase C

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in positive regulation of neurogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
numb-like protein
Names
numb homolog-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072418.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    43751314..43776331 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054674145.1 → XP_054530120.1  numb-like protein isoform X5

  2. XM_054674143.1 → XP_054530118.1  numb-like protein isoform X2

  3. XM_016936028.3 → XP_016791517.2  numb-like protein isoform X1

    UniProtKB/TrEMBL
    A0A2I3RGN5
    Conserved Domains (3) summary
    cd01268
    Location:64 → 229
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:318 → 402
    NumbF; NUMB domain
    cl26386
    Location:403 → 616
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  4. XM_054674144.1 → XP_054530119.1  numb-like protein isoform X4

  5. XM_016936029.3 → XP_016791518.2  numb-like protein isoform X3

    UniProtKB/TrEMBL
    A0A2I3RGN5, A0A2J8QG17
    Conserved Domains (3) summary
    cd01268
    Location:64 → 198
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:287 → 371
    NumbF; NUMB domain
    cl26386
    Location:372 → 585
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
Nucleotide Protein
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