MAP2K6 mitogen-activated protein kinase kinase 6 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: MAP2K6provided by VGNC
Official Full Name: mitogen-activated protein kinase kinase 6provided by VGNC
Primary source: VGNC:VGNC:9365
Locus tag: CK820_G0038067
See related: Ensembl:ENSPTRG00000009588
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	19	NC_072417.2 (82390176..82530657)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	17	NC_072415.1 (80574656..80715106)

Chromosome 19 - NC_072417.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

RH65796 (e-PCR)
- UniSTS:27196

D17S1526 (e-PCR)
- UniSTS:12639

D17S1471E (e-PCR)
- UniSTS:151679

G20292 (e-PCR)
- UniSTS:17318

A005K40 (e-PCR)
- UniSTS:17319

D17S1786 (e-PCR)
- UniSTS:43983

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables MAP kinase kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in MAPK cascade	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: dual specificity mitogen-activated protein kinase kinase 6

XP_009431432.1

EC 2.7.12.2

XP_063655986.1

EC 2.7.12.2

XP_523699.2

EC 2.7.12.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072417.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

82390176..82530657

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_523699.9 → XP_523699.2 dual specificity mitogen-activated protein kinase kinase 6 isoform X1

See identical proteins and their annotated locations for XP_523699.2

UniProtKB/TrEMBL

A0A2I3RB56, A0A2J8KKV1, A0A6D2WAD6, H2QZW5

Related

ENSPTRP00000039686.3

Conserved Domains (1) summary

cd06617
Location:51 → 333

PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6
XM_009433157.5 → XP_009431432.1 dual specificity mitogen-activated protein kinase kinase 6 isoform X2

See identical proteins and their annotated locations for XP_009431432.1

UniProtKB/TrEMBL

A0A2I3RB56, A0A2I3T777, A0A2J8KKV2, A0A6D2XQ66

Conserved Domains (1) summary

cd06617
Location:1 → 277

PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6
XM_063799916.1 → XP_063655986.1 dual specificity mitogen-activated protein kinase kinase 6 isoform X2

UniProtKB/TrEMBL

A0A2I3T777, A0A2J8KKV2, A0A6D2XQ66