NFKBIA NFKB inhibitor alpha [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: NFKBIAprovided by VGNC
Official Full Name: NFKB inhibitor alphaprovided by VGNC
Primary source: VGNC:VGNC:8204
Locus tag: CK820_G0020417
See related: Ensembl:ENSPTRG00000006265
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	15	NC_072413.2 (33636341..33642564, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	14	NC_072412.1 (26876425..26879855, complement)

Chromosome 15 - NC_072413.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

D14S1326 (e-PCR)
- UniSTS:35158

PMC152543P2 (e-PCR)
- UniSTS:271226

GDB:366518 (e-PCR)
- UniSTS:156813

G44344 (e-PCR)
- UniSTS:95131

NFKBIA (e-PCR)
- UniSTS:480425

PMC135646P3 (e-PCR)
- UniSTS:270767

NFKBIA_2537.2 (e-PCR)
- UniSTS:466357

NFKBIA (e-PCR)
- UniSTS:264121

RH69167 (e-PCR)
- UniSTS:75491

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables NF-kappaB binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cellular response to tumor necrosis factor	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cytoplasmic sequestering of NF-kappaB	IEA Inferred from Electronic Annotation more info	PubMed
involved_in toll-like receptor 4 signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: NF-kappa-B inhibitor alpha

Names: nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072413.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

33636341..33642564 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_522823.8 → XP_522823.2 NF-kappa-B inhibitor alpha

See identical proteins and their annotated locations for XP_522823.2

UniProtKB/TrEMBL

A0A2I3S2B2, A0A2J8MI25, A0A6D2XF86, H2Q867

Related

ENSPTRP00000010634.5

Conserved Domains (4) summary

COG0666
Location:57 → 166

ANKYR; Ankyrin repeat [Signal transduction mechanisms]

sd00045
Location:143 → 180

ANK; ANK repeat [structural motif]

pfam00023
Location:216 → 247

Ank; Ankyrin repeat

pfam12796
Location:115 → 212

Ank_2; Ankyrin repeats (3 copies)